PCDHGC3 (NM_032402) Human Untagged Clone

CAT#: SC310078

PCDHGC3 (untagged)-Human protocadherin gamma subfamily C, 3 (PCDHGC3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHGC3
• Synonyms: PC43; PCDH-GAMMA-C3; PCDH2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032402, the custom clone sequence may differ by one or more nucleotides
  ATGGTCCCAGAGGCCTGGAGGAGCGGACTGGTAAGCACCGGGAGGGTAGTGGGAGTTTTG
  CTTCTGCTTGGTGCCTTGAACAAGGCTTCCACGGTCATTCACTATGAGATCCCGGAGGAA
  AGAGAGAAGGGTTTCGCTGTGGGCAACGTGGTCGCGAACCTTGGTTTGGATCTCGGTAGC
  CTCTCAGCCCGCAGGTTCCGGGTGGTGTCTGGAGCTAGCCGAAGATTCTTTGAGGTGAAC
  CGGGAGACCGGAGAGATGTTTGTGAACGACCGTCTGGATCGAGAGGAGCTGTGTGGGACA
  CTGCCCTCTTGCACTGTAACTCTGGAGTTGGTAGTGGAGAACCCGCTGGAGCTGTTCAGC
  GTGGAAGTGGTGATCCAGGACATCAACGACAACAATCCTGCTTTCCCTACCCAGGAAATG
  AAATTGGAGATTAGCGAGGCCGTGGCTCCGGGGACGCGCTTTCCGCTCGAGAGCGCGCAC
  GATCCCGATGTGGGAAGCAACTCTTTACAAACCTATGAGCTGAGCCGAAATGAATACTTT
  GCGCTTCGCGTGCAGACGCGGGAGGACAGCACCAAGTACGCGGAGCTGGTGTTGGAGCGC
  GCCCTGGACCGAGAACGGGAGCCTAGTCTCCAGTTAGTGCTGACGGCGTTGGACGGAGGG
  ACCCCAGCTCTCTCCGCCAGCCTGCCTATTCACATCAAGGTGCTGGACGCGAATGACAAT
  GCGCCTGTCTTCAACCAGTCCTTGTACCGGGCGCGCGTCCTGGAGGATGCACCCTCCGGC
  ACGCGCGTGGTACAAGTCCTTGCAACGGATCTGGATGAAGGCCCCAACGGTGAAATTATT
  TACTCCTTCGGCAGCCACAACCGCGCCGGCGTGCGGCAACTATTCGCCTTAGACCTTGTA
  ACCGGGATGCTGACAATCAAGGGTCGGCTGGACTTCGAGGACACCAAACTCCATGAGATT
  TACATCCAGGCCAAAGACAAGGGCGCCAATCCCGAAGGAGCACATTGCAAAGTGTTGGTG
  GAGGTTGTGGATGTGAATGACAACGCCCCGGAGATCACAGTCACCTCCGTGTACAGCCCA
  GTACCCGAGGATGCCCCTCTGGGGACTGTCATCGCTTTGCTCAGTGTGACTGACCTGGAT
  GCTGGCGAGAACGGGCTGGTGACCTGCGAAGTTCCACCGGGTCTCCCTTTCAGCCTTACT
  TCTTCCCTCAAGAATTACTTCACTTTGAAAACCAGTGCAGACCTGGATCGGGAGACTGTG
  CCAGAATACAACCTCAGCATCACCGCCCGAGACGCCGGAACCCCTTCCCTCTCAGCCCTT
  ACAATAGTGCGTGTTCAAGTGTCCGACATCAATGACAACCCTCCACAATCTTCTCAATCT
  TCCTACGACGTTTACATTGAAGAAAACAACCTCCCCGGGGCTCCAATACTAAACCTAAGT
  GTCTGGGACCCCGACGCCCCGCAGAATGCTCGGCTTTCTTTCTTTCTCTTGGAGCAAGGA
  GCTGAAACCGGGCTAGTGGGTCGCTATTTCACAATAAATCGTGACAATGGCATAGTGTCA
  TCCTTAGTGCCCCTAGACTATGAGGATCGGCGGGAATTTGAATTAACAGCTCATATCAGC
  GATGGGGGCACCCCGGTCCTAGCCACCAACATCAGCGTGAACATATTTGTCACTGATCGC
  AATGACAATGCCCCCCAGGTCCTATATCCTCGGCCAGGTGGGAGCTCGGTGGAGATGCTG
  CCTCGAGGTACCTCAGCTGGCCACCTAGTGTCACGGGTGGTAGGCTGGGACGCGGATGCA
  GGGCACAATGCCTGGCTCTCCTACAGTCTCTTGGGATCCCCTAACCAGAGCCTTTTTGCC
  ATAGGGCTGCACACTGGTCAAATCAGTACTGCCCGTCCAGTCCAAGACACAGATTCACCC
  AGGCAGACTCTCACGGTCTTGATCAAAGACAATGGGGAGCCTTCGCTCTCCACCACTGCT
  ACCCTCACTGTGTCAGTAACCGAGGACTCTCCTGAAGCCCGAGCCGAGTTCCCCTCTGGC
  TCTGCCCCCCGGGAGCAGAAAAAAAATCTCACCTTTTATCTACTTCTTTCTCTAATCCTG
  GTTTCTGTGGGGTTTGTGGTCACAGTGTTCGGAGTAATCATATTCAAAGTTTACAAGTGG
  AAGCAGTCTAGAGACCTATACCGAGCCCCGGTGAGCTCACTGTACCGAACACCAGGGCCC
  TCCTTGCACGCGGACGCCGTGCGGGGAGGCCTGATGTCGCCGCACCTTTACCATCAGGTG
  TATCTCACCACGGACTCCCGCCGCAGCGACCCGCTGCTGAAGAAACCTGGTGCAGCCAGT
  CCACTGGCCAGCCGCCAGAACACGCTGCGGAGCTGTGATCCGGTGTTCTATAGGCAGGTG
  TTGGGTGCAGAGAGCGCCCCTCCCGGACAGGTAAGGTTTAGCAAGTCATGCTTGACCCTG
  TTAGTGCTTTTTTATTCCTACATCATATTGAGGAAGGAATGGAGCTGTTTTTTTAGTGAT
  GAAGATGTTTTCCTGGTGATGCATTCACACTTTCAACTGGCCCTTCCTAGATCAAAGTTA
  GTGCCTTTGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_032402
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_032402.1, NP_115778.1
• RefSeq Size: 2794 bp
• RefSeq ORF: 2592 bp
• Locus ID: 5098
• Cytogenetics: 5q31.3
• Domains: CA
• Protein Families: Transmembrane
• Gene Summary: 'This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes the shorter isoform (2).