RASA4 (NM_006989) Human Untagged Clone

CAT#: SC310102

RASA4 (untagged)-Human RAS p21 protein activator 4 (RASA4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASA4
• Synonyms: CAPRI; GAPL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006989, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCAAGCGCAGCTCGCTGTACATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAGGACATCACTG
  GCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCCCATCATCAGGACAGCCACAGTGTGGAA
  GACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCACCTGCCGCCCACCTTCCACGCTGTGGCTTTC
  TATGTCATGGATGAGGATGCCCTCAGCCGGGACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCA
  TAGCCTCTCACCCTAAGGGTTTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCA
  GGGCGAGATCCACCTGCGGCTGGAAGTGTGGCCAGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTG
  GAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGTCCGAGTGCGCTACAAGG
  GCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGGAATGAGACGTTTGAATTTGA
  GCTGCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCCTGGGACTGGGACCTTGTCAGCCGAAACGAC
  TTCCTGGGCAAAGTGGTGATTGATGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGC
  TGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGAGGGCAACCTGGGCTCCTTGCAGCTGGAGGTGCG
  GCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCACGAGGTC
  AAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCC
  AGGACGTGGCCACGAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCT
  CTTCCAGCTGGAGCTGAGTCGCACCAGTGAGACCAACACCCTGTTCCGGAGCAACTCTCTGGCCTCAAAG
  TCCATGGAGTCTTTTCTGAAGGTGGCCGGGATGCAGTACCTGCACGGCGTCCTGGGCCCCATCATCAACA
  AGGTGTTTGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTC
  CGGGCTGCACCGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTG
  GGGGCCCTGCTGAGCGCGCTCAGCCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCCACCTTCCGCC
  AGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCACGAGAATGTACCGTTCATCGCCGTCAC
  CAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATGTCGCCCAAGCTCTTCCACCTGCGGGAGCGC
  CACGCGGACGCCCGCACCAGCCGCACCCTGCTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGG
  ACACGCCGGCTTCCAGGGCCAAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGC
  GCAGCTGAAGGACTTCATCACCAAGCTCGTGGACATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACG
  CTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGACCAAGGGCAAGGGCCCCC
  TCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCCCTCAGCTTCGCGAAGACGCC
  CAGCTCCAAGAAAAGCGCCCTCATCAAGTTAGCCAACATCCGGGCAGCGGAAAAGGTTGAGGAAAAGAGC
  TTTGGCGGCTCGCACGTCATGCAGGTCATCTACACGGACGACGCCGGCAGGCCCCAGACTGCCTACCTGC
  AGTGCAAGTGTGTGAATGAGCTTAACCAGTGGCTGTCTGCGCTGCGGAAGGTGAGCATCAACAACACCGG
  ACTGCTGGGCTCCTACCACCCTGGCGTCTTCCGTGGGGACAAGTGGAGCTGCTGCCACCAAAAAGAGAAG
  ACAGGTCAGGGCTGCGATAAGACCCGGTCACGGGTGACCCTGCAGGAGTGGAATGACCCTCTTGACCATG
  ACCTTGAGGCCCAGCTCATCTACCGGCACCTGCTGGGCGTGGAGGCCATGCTGTGGGAGAGGCACCGGGA
  GCTGAGCGGGGGCGCAGAGGCAGGCACGGTGCCCACGAGCCCTGGCAAAGTCCCCGAGGACTCATTGGCC
  CGGCTGCTCCGGGTGCTGCAGGACCTCCGCGAGGCCCATAGCTCCAGCCCGGCCGGCTCCCCACCCTCAG
  AGCCCAACTGCCTCCTGGAGCTGCAGACGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_006989
• ORF Size: 2412 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006989.5, NP_008920.5
• RefSeq Size: 5606
• RefSeq ORF: 2412
• Locus ID: 10156
• Domains: C2, BTK, PH, RasGAP
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.