NUP88 (NM_002532) Human Untagged Clone

CAT#: SC310134

NUP88 (untagged)-Human nucleoporin 88kDa (NUP88)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NUP88
• Synonyms: FADS4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002532 edited
  ATGGCGGCCGCCGAGGGACCGGTGGGCGACGGCGAGCTGTGGCAGACCTGGCTTCCTAAC
  CACGTCGTGTTCTTGCGGCTCCGGGAGGGACTGAAAAACCAGAGTCCAACCGAAGCTGAG
  AAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTG
  GTCTTTGGCCTCGGCGGAGAGCTTTTCCTGTGGGACGGAGAAGACAGCTCCTTCTTAGTC
  GTTCGCCTTCGGGGCCCCAGCGGCGGCGGCGAAGAGCCCGCCCTGTCCCAGTACCAGAGA
  TTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAA
  CATCATGTAGCACTTATAGGAATAAAAGGACTTATGGTATTAGAATTACCTAAAAGATGG
  GGGAAGAATTCTGAATTTGAAGGTGGAAAATCAACAGTGAATTGTAGTACCACTCCAGTT
  GCGGAGAGATTTTTCACCAGTTCCACCTCTCTGACTCTAAAGCATGCTGCATGGTATCCA
  AGTGAAATCCTGGATCCCCACGTAGTGCTGTTAACATCAGACAACGTAATCAGAATTTAC
  TCACTACGTGAGCCGCAGACACCCACTAACGTGATAATACTTTCAGAAGCCGAAGAGGAA
  AGTCTAGTACTCAATAAAGGAAGGGCGTATACCGCATCTCTAGGAGAGACAGCAGTTGCA
  TTTGACTTTGGGCCATTGGCAGCAGTCCCAAAGACTCTATTTGGACAAAACGGCAAAGAT
  GAAGTAGTGGCATACCCACTGTACATCTTATATGAAAATGGAGAGACTTTCCTGACATAC
  ATCAGTCTGTTACACAGCCCTGGAAATATTGGAAAGCTGTTGGGTCCATTGCCCATGCAT
  CCTGCGGCTGAAGATAACTATGGTTATGATGCGTGTGCTGTACTCTGCTTACCCTGTGTC
  CCCAATATCTTAGTGATCGCTACTGAATCAGGAATGCTGTATCACTGTGTCGTGCTAGAA
  GGGGAAGAAGAAGATGACCACACGTCAGAAAAGTCCTGGGATTCCAGGATTGACCTCATT
  CCTTCTCTGTATGTGTTTGAATGTGTTGAGTTGGAGCTTGCTTTGAAACTGGCATCTGGA
  GAGGATGACCCTTTTGATTCTGACTTTTCTTGTCCAGTCAAACTTCATAGAGATCCCAAG
  TGTCCTTCAAGATATCACTGTACTCATGAAGCTGGTGTACATAGTGTTGGGCTAACTTGG
  ATTCATAAACTTCACAAATTTCTTGGATCAGATGAAGAAGATAAGGATAGTTTACAGGAA
  CTCTCTACAGAACAGAAATGCTTTGTTGAACACATCCTTTGTACGAAGCCATTGCCCTGC
  AGGCAGCCAGCTCCAATTCGAGGATTTTGGATTGTACCTGACATTCTGGGACCCACGATG
  ATCTGCATCACCAGTACCTATGAATGCCTCATATGGCCGTTATTAAGTACAGTCCATCCA
  GCGTCTCCTCCCCTGCTTTGTACTCGAGAAGATGTTGAAGTGGCAGAGTCTCCCCTCCGT
  GTTCTGGCTGAAACCCCAGATTCCTTTGAAAAGCATATTAGAAGCATTTTGCAACGTAGT
  GTTGCCAATCCAGCATTTTTGAAAGCTTCTGAAAAGGACATAGCCCCTCCTCCTGAAGAA
  TGCCTTCAGCTCCTCAGCAGAGCCACCCAGGTGTTCAGAGAGCAGTACATTCTCAAACAG
  GACTTGGCAAAGGAGGAGATTCAGCGGAGGGTCAAATTATTATGTGACCAAAAAAAGAAA
  CAACTAGAAGATCTCAGTTATTGTCGAGAAGAGAGGAAAAGTCTGCGGGAAATGGCTGAG
  CGTTTAGCTGACAAATATGAGGAAGCTAAAGAAAAACAAGAGGATATCATGAACAGGATG
  AAAAAACTACTTCACAGTTTTCACTCTGAGCTCCCAGTTCTCTCTGATAGTGAGCGAGAC
  ATGAAGAAAGAATTACAGCTGATACCTGATCAACTTCGACATTTGGGCAATGCCATCAAA
  CAGGTTACTATGAAAAAGGATTATCAACAGCAAAAGATGGAGAAGGTGTTGAGTCTTCCA
  AAACCCACCATTATTCTCAGTGCCTACCAGCGAAAGTGCATTCAGTCCATCCTGAAAGAG
  GAGGGTGAACATATAAGGGAAATGGTGAAGCAAATCAATGATATCCGCAATCATGTAAAC
  TTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_002532
• Insert Size: 2200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002532.3, NP_002523.2
• RefSeq Size: 2381 bp
• RefSeq ORF: 2226 bp
• Locus ID: 4927
• Cytogenetics: 17p13.2
• Gene Summary: 'The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]'
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.