HIF3 alpha (HIF3A) (NM_022462) Human Untagged Clone

CAT#: SC310198

HIF3A (untagged)-Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HIF3A
• Synonyms: bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_022462 edited
  ATGCGCCTCACCATCAGCTACCTGCGCATGCACCGCCTCTGCGCCGCAGGGGAGTGGAAC
  CAGGTGGGAGCAGGGGGAGAACCACTGGATGCCTGCTACCTGAAGGCCCTGGAGGGCTTC
  GTCATGGTGCTCACCGCCGAGGGAGACATGGCTTACCTGTCGGAGAATGTCAGCAAACAC
  CTGGGCCTCAGTCAGCTGGAGCTCATTGGACACAGCATCTTTGATTTCATCCACCCCTGT
  GACCAAGAGGAGCTTCAGGACGCCCTGACCCCCCAGCAGACCCTGTCCAGGAGGAAGGTG
  GAGGCCCCCACGGAGCGGTGCTTCTCCTTGCGCATGAAGAGTACACTCACCAGCCGCGGG
  CGCACCCTCAACCTCAAGGCGGCCACCTGGAAGGTGCTGAACTGCTCTGGACATATGAGG
  GCCTACAAGCCACCTGCGCAGACTTCTCCAGCTGGGAGCCCTGACTCAGAGCCCCCGCTG
  CAGTGCCTGGTGCTCATCTGCGAAGCCATCCCCCACCCAGGCAGCCTGGAGCCCCCACTG
  GGCCGAGGGGCCTTCCTCAGCCGCCACAGCCTGGACATGAAGTTCACCTACTGTGACGAC
  AGGATTGCAGAAGTGGCTGGCTATAGTCCCGATGACCTGATCGGCTGTTCCGCCTACGAG
  TACATCCACGCGCTGGACTCCGACGCGGTCAGCAAGAGCATCCACACCTTGCTGAGCAAG
  GGCCAGGCAGTAACAGGGCAGTATCGCTTCCTGGCCCGGAGTGGTGGCTACCTGTGGACC
  CAGACCCAGGCCACAGTGGTGTCAGGGGGACGGGGCCCCCAGTCGGAGAGTATCGTCTGT
  GTCCATTTTTTAATCAGCCGGGTGGAAGAGACCGGAGTGGTGCTGTCCCTGGAGCAAACG
  GAGCAACATTCTCGCAGACCCATTCAGCGGGGCGCCCCCTCTCAGAAGGACACCCCTAAC
  CCTGGGGACAGCCTTGACACCCCTGGCCCCCGGATCCTTGCCTTCCTGCACCCGCCTTCC
  CTGAGCGAGGCTGCCCTGGCCGCTGACCCCCGCCGTTTCTGCAGCCCTGACCTCCGTCGC
  CTCCTGGGACCCATCCTGGATGGGGCTTCAGTAGCAGCCACTCCCAGCACCCCGCTGGCC
  ACACGGCACCCCCAAAGTCCTCTTTCGGCTGATCTCCCAGATGAACTACCTGTGGGCACC
  GAGAATGTGCACAGACTCTTCACCTCCGGGAAAGACACTGAGGCAGTGGAGACAGATTTA
  GATATAGCTCAGGATGCTGATGCTCTGGATTTGGAGATGCTGGCCCCCTACATCTCCATG
  GATGATGACTTCCAGCTCAACGCCAGCGAGCAGCTACCCAGGGCCTACCACAGACCTCTG
  GGGGCTGTCCCCCGGCCCCGTGCTCGGAGCTTCCATGGCCTGTCACCTCCAGCCCTTGAG
  CCCTCCCTGCTACCCCGCTGGGGGAGTGACCCCCGGCTGAGCTGCTCCAGCCCTTCCAGA
  GGGGACCCCTCAGCATCCTCTCCCATGGCTGGGGCTCGGAAGAGGACCCTGGCCCAGAGC
  TCAGAGGACGAGGACGAGGGAGTGGAGCTGCTGGGAGTGAGACCTCCCAAAAGGTCCCCC
  AGCCCAGAACACGAAAACTTTCTGCTCTTTCCTCTCAGCCTGAGTTTCCTTCTGACAGGA
  GGACCAGCCCCAGGGAGCCTGCAGGACCCCAGCACCCCACTCCTGAACCTGAATGAGCCC
  CTGGGCCTGGGCCCCTCACTGCTCTCTCCGTACTCAGACGAGGACACTACCCAGCCCGGG
  GGCCCCTTCCAGCCAAGGGCAGGCTCAGCCCAGGCTGACTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_022462
• ORF Size: 1947 bp
• Insert Size: 1900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_022462.2.

Reference Data

• RefSeq: NM_022462.2, NP_071907.2
• RefSeq Size: 2626
• RefSeq ORF: 1947
• Locus ID: 64344
• Domains: PAS
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 3. The resulting isoform (b) has a distinct and shorter N-terminus, compared to isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.