DYRK1B (NM_006483) Human Untagged Clone

CAT#: SC310235

DYRK1B (untagged)-Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B), transcript variant b

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DYRK1B
• Synonyms: AOMS3; MIRK
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006483, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCGTCCCACCGGGCCATGGTCCCTTCTCTGGCTTCCCAGGGCCCCAGGAGCACACGCAGGTATTGC
  CTGATGTGCGGCTACTGCCTCGGAGGCTGCCCCTGGCCTTCCGGGATGCAACCTCAGCCCCGCTGCGTAA
  GCTCTCTGTGGACCTCATCAAGACCTACAAGCACATCAATGAGGTATACTATGCGAAGAAGAAGCGGCGG
  GCCCAGCAGGCGCCACCCCAGGATTCGAGCAACAAGAAGGAGAAGAAGGTCCTGAACCATGGTTATGATG
  ACGACAACCATGACTACATCGTGCGCAGTGGCGAGCGCTGGCTGGAGCGCTACGAAATTGACTCGCTCAT
  TGGCAAAGGCTCCTTTGGCCAGGTGGTGAAAGCCTATGATCATCAGACCCAGGAGCTTGTGGCCATCAAG
  ATCATCAAGAACAAAAAGGCTTTCCTGAACCAGGCCCAGATTGAGCTGCGGCTGCTGGAGCTGATGAACC
  AGCATGACACGGAGATGAAGTACTATATAGTACACCTGAAGCGGCACTTCATGTTCCGGAACCACCTGTG
  CCTGGTATTTGAGCTGCTGTCCTACAACCTGTACGACCTCCTGCGCAACACCCACTTCCGCGGCGTCTCG
  CTGAACCTGACCCGGAAGCTGGCGCAGCAGCTCTGCACGGCACTGCTCTTTCTGGCCACGCCTGAGCTCA
  GCATCATTCACTGCGACCTCAAGCCCGAAAACATCTTGCTGTGCAACCCCAAGCGCAGCGCCATCAAGAT
  TGTGGACTTCGGCAGCTCCTGCCAGCTTGGCCAGAGGATCTACCAGTATATCCAGAGCCGCTTCTACCGC
  TCACCTGAGGTGCTCCTGGGCACACCCTACGACCTGGCCATTGACATGTGGTCCCTGGGCTGCATCCTTG
  TGGAGATGCACACCGGAGAGCCCCTCTTCAGTGGCTCCAATGAGGTCGACCAGATGAACCGCATTGTGGA
  GGTGCTGGGCATCCCACCGGCCGCCATGCTGGACCAGGCGCCCAAGGCTCGCAAGTACTTTGAACGGCTG
  CCTGGGGGTGGCTGGACCCTACGAAGGACGAAAGAACTCAGGAAGGACCTGGTGCTGCGCATGCTGGAGT
  ATGAGCCCGCCGCCCGCATCAGCCCCCTGGGGGCTCTGCAGCACGGCTTCTTCCGCCGCACGGCCGACGA
  GGCCACCAACACGGGCCCGGCAGGCAGCAGTGCCTCCACCTCGCCCGCGCCCCTCGACACCTGCCCCTCT
  TCCAGCACCGCCAGCTCCATCTCCAGTTCTGGAGGCTCCAGTGGCTCCTCCAGTGACAACCGGACCTACC
  GCTACAGCAACCGATATTGTGGGGGCCCTGGGCCCCCTATCACAGACTGTGAGATGAACAGCCCCCAGGT
  CCCACCCTCCCAGCCGCTGCGGCCCTGGGCAGGGGGTGATGTGCCCCACAAGACACATCAAGCCCCTGCC
  TCTGCCTCGTCACTGCCTGGGACCGGGGCCCAGTTACCCCCCCAGCCCCGATACCTTGGTCGTCCCCCAT
  CACCAACCTCACCACCACCCCCGGAGCTGATGGATGTGAGCCTGGTGGGCGGCCCTGCTGACTGCTCCCC
  ACCTCACCCAGCGCCTGCCCCCCAGCACCCGGCTGCCTCAGCCCTCCGGACTCGGATGACTGGAGGTCGT
  CCACCCCTCCCGCCTCCTGATGACCCTGCCACTCTGGGGCCTCACCTGGGCCTCCGTGGTGTACCCCAGA
  GCACAGCAGCCAGCTCGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_006483
• ORF Size: 1770 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006483.2, NP_006474.1
• RefSeq Size: 2468
• RefSeq ORF: 1770
• Locus ID: 9149
• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors
• Gene Summary: This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
  Transcript Variant: This variant (2, also known as 'b') uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (p65, also known as isoform b) is shorter than isoform p69.