ALDH5A1 (NM_170740) Human Untagged Clone

CAT#: SC310277

ALDH5A1 (untagged)-Human aldehyde dehydrogenase 5 family, member A1 (ALDH5A1), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH5A1
• Synonyms: SSADH; SSDH
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_170740, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGCCCGGCGCCTCGGGTCGACGTTTCCAGGCTGCCGCC
  TCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGCCCAGCTCCGCTGCTA
  CGCTGGGCGCCTGGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTC
  CCGGCCGCCGCCACCTTCCCCGTGCAAGACCCGGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCG
  GGGTGCGAGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGAGGCTTTCTGCCGCTGGAGGGAGGTCTCCGC
  CAAGGAGAGGAGTTCATTACTTCGGAAGTGGTACAATTTAATGATACAAAATAAGGATGACCTTGCCAGA
  ATAATCACAGCTGAAAGTGGAAAGCCACTGAAGGAGGCACATGGAGAAATTCTCTATTCCGCCTTTTTCC
  TAGAGTGGTTCTCTGAGGAAGCCCGCCGTGTTTACGGAGACATTATCCACACCCCGGCAAAGGACAGGCG
  GGCCCTGGTCCTCAAGCAGCCCATAGGCGTGGCTGCAGTCATCACCCCGTGGAATTTCCCCAGTGCCATG
  ATCACCCGGAAGGTGGGGGCCGCCCTGGCAGCCGGCTGTACTGTCGTGGTGAAGCCTGCCGAAGACACGC
  CCTTCTCCGCCCTGGCCCTGGCTGAGGTAAATCAGGGATTTCTTCTTGATTTGGATCCATTGTTGCTTGC
  AAGCCAGGCTGGGATTCCTTCAGGTGTATACAATGTTATTCCCTGTTCTCGAAAGAATGCCAAGGAAGTA
  GGGGAGGCAATTTGTACTGATCCTCTGGTGTCCAAAATTTCCTTTACTGGTTCAACAACTACAGGAAAGA
  TCCTGTTGCACCACGCAGCAAACTCTGTGAAAAGGGTCTCTATGGAGCTGGGCGGCCTTGCTCCATTTAT
  AGTATTTGACAGTGCCAACGTGGACCAGGCTGTAGCAGGGGCCATGGCATCTAAATTTAGGAACACTGGA
  CAGACTTGTGTTTGCTCAAACCAATTCTTGGTGCAAAGGGGCATCCATGATGCCTTTGTAAAAGCATTCG
  CCGAGGCCATGAAGAAGAACCTGCGCGTAGGTAATGGATTTGAGGAAGGAACTACTCAGGGCCCATTAAT
  TAATGAAAAAGCGGTAGAAAAGGTGGAGAAACAGGTGAATGATGCCGTTTCTAAAGGTGCCACCGTTGTG
  ACAGGTGGAAAACGACACCAACTTGGAAAAAATTTCTTTGAGCCTACCCTGCTGTGCAATGTCACCCAGG
  ACATGCTGTGCACTCATGAAGAGACTTTCGGGCCTCTGGCACCAGTTATCAAGTTCGATACAGAGGAGGA
  GGCTATAGCAATCGCTAACGCAGCTGATGTTGGGTTAGCAGGTTATTTTTACTCTCAAGACCCAGCCCAG
  ATCTGGAGAGTGGCAGAGCAGCTGGAAGTGGGCATGGTTGGCGTCAACGAAGGATTAATTTCCTCTGTGG
  AGTGCCCTTTTGGTGGAGTGAAGCAGTCCGGCCTTGGGCGAGAGGGGTCCAAGTATGGCATTGATGAGTA
  TCTGGAACTCAAGTATGTGTGTTACGGGGGCTTGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_170740
• ORF Size: 1647 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_170740.1, NP_733936.1
• RefSeq Size: 5170
• RefSeq ORF: 1647
• Locus ID: 7915
• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, Metabolic pathways
• Gene Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (1).