Calcineurin A (PPP3CA) (NM_000944) Human Untagged Clone

CAT#: SC310299

PPP3CA (untagged)-Human protein phosphatase 3, catalytic subunit, alpha isozyme (PPP3CA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPP3CA
• Synonyms: ACCIID; CALN; CALNA; CALNA1; CCN1; CNA1; IECEE; IECEE1; PPP2B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000944 edited
  AGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGGCTGGCG
  GCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAG
  CAACTTTAAAGCCAGCTCAGAGCCTAGACCTCCAGCCGAGTGGTTTGCAGCGCGGCGGCG
  GCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGC
  AGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAG
  GCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGCTGTTCCATTTCCTCCA
  AGTCACCGGCTTACAGCAAAAGAAGTGTTTGATAATGATGGAAAACCTCGTGTGGATATC
  TTAAAGGCGCATCTTATGAAGGAGGGAAGGCTGGAAGAGAGTGTTGCATTGAGAATAATA
  ACAGAGGGTGCATCAATTCTTCGACAGGAAAAAAATTTGCTGGATATTGATGCGCCAGTC
  ACTGTTTGTGGGGACATTCATGGACAATTCTTTGATTTGATGAAGCTCTTTGAAGTCGGG
  GGATCTCCTGCCAACACTCGCTACCTCTTCTTAGGGGACTATGTTGACAGAGGGTACTTC
  AGTATTGAATGTGTGCTGTATTTGTGGGCCTTGAAAATTCTCTACCCCAAAACACTGTTT
  TTACTTCGTGGAAATCATGAATGTAGACATCTAACAGAGTATTTCACATTTAAACAAGAA
  TGTAAAATAAAGTATTCAGAACGCGTATATGATGCCTGTATGGATGCCTTTGACTGCCTT
  CCCCTGGCTGCCCTGATGAACCAACAGTTCCTGTGTGTGCATGGTGGTTTGTCTCCAGAG
  ATTAACACTTTAGATGATATCAGAAAATTAGACCGATTCAAAGAACCACCTGCATATGGA
  CCTATGTGTGATATCCTGTGGTCAGACCCCCTGGAAGATTTTGGAAATGAGAAGACTCAG
  GAACATTTCACTCACAACACAGTCAGGGGGTGTTCATACTTCTACAGTTACCCGGCTGTA
  TGTGAATTCTTACAGCACAATAACTTGTTATCTATACTCCGAGCCCACGAAGCCCAAGAT
  GCAGGGTACCGCATGTACAGGAAAAGCCAAACAACAGGCTTCCCTTCTCTAATTACAATT
  TTTTCAGCACCAAATTACTTAGATGTATACAATAACAAAGCTGCAGTATTGAAGTATGAG
  AACAATGTTATGAATATCAGGCAATTCAACTGTTCTCCTCATCCATACTGGCTTCCAAAT
  TTCATGGATGTTTTTACTTGGTCCCTTCCATTTGTTGGGGAAAAAGTGACTGAGATGCTG
  GTAAATGTCCTCAACATCTGCTCAGATGATGAACTAGGGTCAGAAGAAGATGGATTTGAT
  GGTGCAACAGCTGCAGCCCGGAAAGAGGTGATAAGGAACAAGATCCGAGCAATAGGCAAA
  ATGGCCAGAGTGTTCTCAGTGCTCAGAGAAGAGAGTGAGAGTGTGCTGACGCTGAAAGGC
  TTGACCCCAACTGGCATGCTCCCCAGCGGAGTACTTTCTGGAGGGAAGCAAACCCTGCAA
  AGCGCTACTGTTGAGGCTATTGAGGCTGATGAAGCTATCAAAGGATTTTCACCACAACAT
  AAGATCACTAGCTTCGAGGAAGCCAAGGGCTTAGACCGAATTAATGAGAGGATGCCGCCT
  CGCAGAGATGCCATGCCCTCTGACGCCAACCTTAACTCCATCAACAAGGCTCTCACCTCA
  GAGACTAACGGCACGGACAGCAATGGCAGTAATAGCAGCAATATTCAGTGACCACTTCCT
  GTTCACTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCTGCGGGGCATGATGGGGATTGC
  TGCATATCAGCAGTTGGATGTTCTTGCCTCTGACAGTAGCTTATTTGCTCTGGGGGCCAG
  GAATTGGATTCAGTTTACACTATCATTAAAAAAGAGGGAGAGAGATAATAAACTATATTT
  TGGTGGGGATGGTGATTAAACACCTCTTTTGGGTATGCCTTTTAAAAATGCTTATAGAGA
  AAAAAAATTTTAAAAAGAAAGCTAATGCTAGTATATACTGCAATGTTAGGGGAATGAACA
  TGTTTTCCTACTGCATTGGGGACTTCTAGATAGGTTAATGAAAGGCCTTTTATTCTGTTA
  CTGGACATGAAAACTTTGTCTAATTTCTTACTCTATTGTACGTTTACAGTCGCAGCACTA
  AAAATGGATGACATCAAACATTTTTAACAAAATGATGTACAAACTAAGGACTATTTATTG
  ATAATGTTTTGCTACTCTTGTCAGACAATGGCTATAAACTGAATTAGGCAGTCTTAAAAA
  AAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_000944
• Insert Size: 2400 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this clone has been fully sequenced and found to be a perfect match to the protein associated with this reference, NM_000944.3.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000944.2, NP_000935.1
• RefSeq Size: 4425 bp
• RefSeq ORF: 1566 bp
• Locus ID: 5530
• Cytogenetics: 4q24
• Domains: Metallophos, PP2Ac
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: ''
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).