TRF1 (TERF1) (NM_003218) Human Untagged Clone

CAT#: SC310415

TERF1 (untagged)-Human telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TERF1
• Synonyms: hTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003218 edited
  ATTTTAACATGGCGGAGGATGTTTCCTCAGCGGCCCCGAGCCCGCGGGGCTGTGCGGATG
  GTAGGGATGCCGACCCTACTGAGGAGCAGATGGCAGAAACAGAGAGAAACGACGAGGAGC
  AGTTCGAATGCCAGGAACTGCTCGAGTGCCAGGTGCAGGTGGGGGCCCCCGAGGAGGAGG
  AGGAGGAGGAGGAGGACGCGGGCCTGGTGGCCGAGGCCGAGGCCGTGGCTGCCGGCTGGA
  TGCTCGATTTCCTCTGCCTCTCTCTTTGCCGAGCTTTCCGCGACGGCCGCTCCGAGGACT
  TCCGCAGGACCCGCAACAGCGCAGAGGCTATTATTCATGGACTATCCAGTCTAACAGCTT
  GCCAGTTGAGAACGATATACATATGTCAGTTTTTGACAAGAATTGCAGCAGGAAAAACCC
  TTGATGCACAGTTTGAAAATGATGAACGAATTACACCCTTGGAATCAGCCCTGATGATTT
  GGGGTTCAATTGAAAAGGAACATGACAAACTTCATGAAGAAATACAGAATTTAATTAAAA
  TTCAGGCTATAGCTGTTTGTATGGAAAATGGCAACTTTAAAGAAGCAGAAGAAGTCTTTG
  AAAGAATATTTGGTGATCCAAATTCTCATATGCCTTTCAAAAGCAAATTGCTTATGATAA
  TCTCTCAGAAAGATACATTTCATTCCTTTTTTCAACACTTCAGCTACAACCACATGATGG
  AGAAAATTAAGAGTTATGTGAATTATGTGCTAAGTGAAAAATCATCAACCTTTCTAATGA
  AGGCAGCGGCAAAAGTAGTAGAAAGCAAAAGGACAAGAACAATAACTTCTCAAGATAAAC
  CTAGTGGTAATGATGTTGAAATGGAAACTGAAGCTAATTTGGATACAAGAAAAAGGTCTC
  ACAAGAATCTTTTCTTATCTAAGTTGCAACATGGAACCCAGCAACAAGACCTTAATAAGA
  AAGAAAGAAGAGTAGGAACTCCTCAAAGTACAAAAAAGAAAAAAGAAAGCAGAAGAGCCA
  CTGAAAGCAGAATACCTGTTTCAAAGAGTCAGCCGGTAACTCCTGAAAAACATCGAGCTA
  GAAAAAGACAGGCATGGCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAAT
  ATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCGGACAAGTG
  TCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCG
  AAGACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCA
  TTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCATTACAGTA
  TTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATC
  ATTGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATT
  TAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATACGCAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAWR
  
• Restriction Sites: Please inquire
• ACCN: NM_003218
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_003218.2.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003218.2, NP_003209.1
• RefSeq Size: 2626 bp
• RefSeq ORF: 1260 bp
• Locus ID: 7013
• Cytogenetics: 8q21.11
• Domains: myb_DNA-binding
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.