ZFYVE27 (NM_144588) Human Untagged Clone

CAT#: SC310427

ZFYVE27 (untagged)-Human zinc finger, FYVE domain containing 27 (ZFYVE27), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZFYVE27
• Synonyms: PROTRUDIN; SPG33
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_144588, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGACATCAGAACGTGAGGGGAGTGGGCCGGAGCTGAGCCCCAGCGTGATGCCCGAGGCTCCCCTGG
  AGTCTCCACCTTTTCCTACCAAGTCCCCAGCGTTTGACCTTTTCAACTTGGTTCTCTCCTACAAGAGGCT
  GGAGATCTACCTGGAACCCTTGAAGGATGCAGGTGATGGTGTTCGATACTTGCTCAGGTGGCAGATGCCT
  TTGTGTTCCTTGCTGACCTGCCTGGGCCTCAACGTCTTGTTCCTCACTTTGAATGAGGGTGCATGGTACT
  CAGTAGGTGCCCTGATGATTTCAGTGCCCGCCCTGCTGGGCTACCTTCAGGAGGTTTGCCGGGCACGGCT
  GCCTGATTCCGAGCTGATGCGGAGGAAGTATCATAGCGTGAGGCAGGAGGACCTGCAGAGAGGTCGCCTG
  TCTCGTCCCGAGGCCGTGGCTGAGGTGAAGAGCTTCTTGATCCAGCTGGAGGCCTTCCTGAGCCGCCTGT
  GCTGCACATGTGAAGCCGCCTACCGCGTGCTGCACTGGGAGAACCCCGTCGTGTCCTCACAGTTCTATGG
  GGCTCTTCTGGGCACAGTCTGCATGCTGTATTTGCTGCCACTCTGCTGGGTTCTCACCCTTTTAAACAGC
  ACGCTCTTTCTGGGGAATGTGGAGTTCTTCCGAGTTGTGTCTGAGTACAGGGCATCTCTGCAGCAGAGGA
  TGAACCCAAAGCAGGAAGAGCATGCCTTTGAGAGTCCTCCACCACCAGATGTTGGGGGGAAGGATGGTCT
  GATGGACAGCACGCCTGCCCTCACACCCACGGAGGACCTCACACCGGGCAGCGTGGAGGAGGCTGAGGAG
  GCTGAGCCAGATGAAGAGTTTAAAGATGCGATTGAGGAGACCCACTTGGTGGTGCTGGAGGATGATGAGG
  GCGCCCCGTGCCCAGCAGAGGATGAGCTGGCCCTGCAGGACAACGGGTTCCTGAGCAAGAATGAGGTGCT
  GCGCAGCAAGGTGTCTCGGCTCACGGAGCGGCTCCGCAAGCGCTACCCCACCAACAACTTCGGGAACTGC
  ACGGGCTGCTCGGCCACCTTCTCAGTGCTGAAGAAGAGGCGGAGCTGCAGTAATTGTGGAAACAGCTTCT
  GCTCTCGATGCTGCTCCTTCAAGGTGCCCAAGTCCTCCATGGGGGCCACAGCCCCTGAAGCCCAGAGGGA
  GACTGTGTTTGTGTGTGCCTCGTGTAACCAGACCTTGAGCAAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_144588
• ORF Size: 1236 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_144588.6, NP_653189.3
• RefSeq Size: 3059
• RefSeq ORF: 1236
• Locus ID: 118813
• Domains: FYVE
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the middle portion of the coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.