LIMS2 (NM_017980) Human Untagged Clone

CAT#: SC310488

LIMS2 (untagged)-Human LIM and senescent cell antigen-like domains 2 (LIMS2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LIMS2
• Synonyms: LGMD2W; MDRCMTT; PINCH-2; PINCH2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017980, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCCGGCTGGGTGCGCTGGCCGCGTCGGGGCTGTACCGGCGGCGCCAGCACCGGCAGAGCCCGC
  CGCCAGCCACGGGCAATATGTCGGACGCCTTGGCCAACGCCGTGTGCCAGCGCTGCCAGGCCCGCTTCTC
  CCCCGCCGAGCGCATTGTCAACAGCAATGGGGAGCTGTACCATGAGCACTGCTTCGTGTGTGCCCAGTGC
  TTCCGGCCCTTCCCCGAGGGGCTCTTCTATGAGTTTGAAGGCCGGAAGTACTGCGAACACGACTTCCAAA
  TGCTGTTTGCTCCGTGCTGTGGATCCTGCGGTGAGTTCATCATTGGCCGCGTCATCAAGGCCATGAACAA
  CAACTGGCACCCGGGCTGCTTCCGCTGCGAGCTGTGTGATGTGGAGCTGGCTGACCTGGGCTTTGTGAAG
  AATGCCGGCAGGCATCTCTGCCGGCCTTGCCACAACCGTGAGAAGGCCAAGGGCCTGGGCAAGTACATCT
  GCCAGCGGTGCCACCTGGTCATCGACGAGCAGCCCCTCATGTTCAGGAGCGACGCCTACCACCCTGACCA
  CTTCAACTGCACCCACTGTGGGAAGGAGCTGACAGCCGAGGCCCGCGAGCTGAAGGGTGAGCTCTACTGC
  CTGCCCTGCCATGACAAGATGGGCGTCCCCATCTGCGGGGCCTGCCGCCGGCCCATCGAGGGCCGAGTGG
  TCAACGCGCTGGGCAAGCAGTGGCACGTGGAGCACTTTGTCTGTGCCAAGTGTGAGAAGCCATTCCTGGG
  GCACCGGCACTATGAGAAGAAGGGCCTGGCCTACTGCGAGACTCACTACAACCAGCTCTTCGGGGACGTC
  TGCTACAACTGCAGCCATGTGATTGAAGGCGATGTGGTGTCGGCCCTCAACAAGGCCTGGTGTGTGAGCT
  GCTTCTCCTGCTCCACCTGCAACAGCAAGCTCACCCTGAAGAACAAGTTTGTGGAGTTCGACATGAAGCC
  CGTGTGTAAGAGGTGCTACGAGAAGTTCCCGCTGGAGCTGAAGAAGCGGCTGAAGAAGCTGTCGGAGCTG
  ACCTCCCGCAAGGCCCAGCCCAAGGCCACAGACCTCAACTCTGCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_017980
• ORF Size: 1098 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017980.4, NP_060450.2
• RefSeq Size: 2173
• RefSeq ORF: 1098
• Locus ID: 55679
• Domains: LIM
• Gene Summary: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.