ZNF384 (NM_001039916) Human Untagged Clone

CAT#: SC311090

ZNF384 (untagged)-Human zinc finger protein 384 (ZNF384), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZNF384
• Synonyms: CAGH1; CAGH1A; CIZ; ERDA2; FLJ59043; NMP4; NP; TNRC1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001039916, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGAATCTCACTTCAATTCTAACCCGTACTTCTGGCCTTCTATCCCCACAGTCTCAGGTCAGATCG
  AGAACACAATGTTCATCAACAAGATGAAGGATCAGCTGTTGCCAGAGAAGGGCTGTGGTCTGGCCCCACC
  TCACTACCCCACCTTGCTGACAGTGCCTGCCTCAGTGTCCCTGCCCTCAGGCATCAGTATGGACACAGAG
  TCCAAGTCAGACCAGCTGACCCCACACAGCCAAGCGTCCGTTACCCAGAATATCACGGTGGTCCCTGTGC
  CGTCTACAGGACTGATGACTGCTGGAGTCTCCTGTTCTCAGAGGTGGAGAAGAGAAGGGAGTCAATCAAG
  GGGTCCGGGTTTGGTAATCACGTCCCCCTCAGGCTCTCTTGTGACCACAGCATCATCAGCTCAGACCTTC
  CCCATTTCGGCTCCCATGATTGTCTCAGCTCTTCCCCCTGGCTCACAAGCCCTGCAGGTTGTCCCTGACC
  TCTCCAAGAAGGTAGCATCGACCCTAACCGAGGAAGGAGGCGGAGGTGGTGGTGGAGGTGGCAGTGTGGC
  TCCTAAGCCACCCCGGGGCCGGAAGAAGAAGCGGATGCTGGAATCAGGGCTGCCCGAGATGAATGACCCT
  TATGTCCTCTCCCCTGAGGATGATGATGACCATCAGAAAGACGGCAAGACCTACAGGTGCCGGATGTGCT
  CACTGACATTCTACTCCAAGTCGGAGATGCAGATCCACTCCAAGTCACACACCGAGACCAAGCCCCACAA
  GTGCCCACATTGCTCCAAGACCTTCGCCAACAGCTCCTACCTGGCCCAGCACATCCGTATACACTCAGGG
  GCTAAGCCCTACAGTTGTAACTTCTGTGAGAAATCCTTCCGCCAGCTCTCCCACCTTCAGCAGCACACCC
  GAATCCACACTGGTGATAGACCATACAAATGTGCACACCCAGGCTGTGAGAAAGCCTTCACACAACTCTC
  CAATCTGCAGTCCCACAGACGGCAACACAACAAAGATAAACCCTTCAAGTGCCACAACTGTCATCGGGCG
  TACACGGATGCAGCCTCACTAGAGGTGCACCTGTCTACGCACACAGTGAAGCATGCCAAGGTGTACACCT
  GCACTATCTGCAGTCGGGCATACACATCAGAAACATACCTTATGAAACATATGCGCAAACACAACCCGCC
  TGATCTTCAGCAACAGGTGCAGGCAGCAGCAGCAGCGGCAGCAGTGGCCCAGGCCCAGGCTCAAGCTCAA
  GCCCAGGCTCAGGCTCAGGCTCAAGCCCAGGCCCAGGCCCAGGCCTCCCAGGCATCACAGCAGCAGCAGC
  AGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCCACCACCACACTTCCAGTCTCCTGGGGCAGCCCC
  CCAGGGTGGGGGTGGTGGGGACAGCAATCCCAACCCTCCACCCCAGTGTTCCTTTGACCTGACCCCGTAT
  AAGACGGCGGAGCATCATAAGGACATCTGCCTCACTGTCACCACCAGCACCATCCAGGTGGAGCACCTGG
  CCAGCTCTTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001039916
• ORF Size: 1551 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001039916.1, NP_001035005.1
• RefSeq Size: 3286
• RefSeq ORF: 1551
• Locus ID: 171017
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1, 2, and 3 all encode isoform a.