ARTS1 (ERAP1) (NM_001040458) Human Untagged Clone

CAT#: SC311137

ERAP1 (untagged)-Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERAP1
• Synonyms: A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001040458 edited
  GGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGCTGGGCCTCAGGTGAGACTGCAG
  CTCCAGTCATCATCTTGATTGCAGCCCACAGAAACTACCAACCCACAGAAACTGTAGGTA
  GAGCAAGAAGATGGTGTTTCTGCCCCTCAAATGGTCCCTTGCAACCATGTCATTTCTACT
  TTCCTCACTGTTGGCTCTCTTAACTGTGTCCACTCCTTCATGGTGTCAGAGCACTGAAGC
  ATCTCCAAAACGTAGTGATGGGACACCATTTCCTTGGAATAAAATACGACTTCCTGAGTA
  CGTCATCCCAGTTCATTATGATCTCTTGATCCATGCAAACCTTACCACGCTGACCTTCTG
  GGGAACCACGAAAGTAGAAATCACAGCCAGTCAGCCCACCAGCACCATCATCCTGCATAG
  TCACCACCTGCAGATATCTAGGGCCACCCTCAGGAAGGGAGCTGGAGAGAGGCTATCGGA
  AGAACCCCTGCAGGTCCTGGAACACCCCCGTCAGGAGCAAATTGCACTGCTGGCTCCCGA
  GCCCCTCCTTGTCGGGCTCCCGTACACAGTTGTCATTCACTATGCTGGCAATCTTTCGGA
  GACTTTCCACGGATTTTACAAAAGCACCTACAGAACCAAGGAAGGGGAACTGAGGATACT
  AGCATCAACACAATTTGAACCCACTGCAGCTAGAATGGCCTTTCCCTGCTTTGATGAACC
  TGCCTTCAAAGCAAGTTTCTCAATCAAAATTAGAAGAGAGCCAAGGCACCTAGCCATCTC
  CAATATGCCATTGGTGAAATCTGTGACTGTTGCTGAAGGACTCATAGAAGACCATTTTGA
  TGTCACTGTGAAGATGAGCACCTATCTGGTGGCCTTCATCATTTCAGATTTTGAGTCTGT
  CAGCAAGATAACCAAGAGTGGAGTCAAGGTTTCTGTTTATGCTGTGCCAGACAAGATAAA
  TCAAGCAGATTATGCACTGGATGCTGCGGTGACTCTTCTAGAATTTTATGAGGATTATTT
  CAGCATACCGTATCCCCTACCCAAACAAGATCTTGCTGCTATTCCCGACTTTCAGTCTGG
  TGCTATGGAAAACTGGGGACTGACAACATATAGAGAATCTGCTCTGTTGTTTGATGCAGA
  AAAGTCTTCTGCATCAAGTAAGCTTGGCATCACAATGACTGTGGCCCATGAACTGGCTCA
  CCAGTGGTTTGGGAACCTGGTCACTATGGAATGGTGGAATGATCTTTGGCTAAATGAAGG
  ATTTGCCAAATTTATGGAGTTTGTGTCTGTCAGTGTGACCCATCCTGAACTGAAAGTTGG
  AGATTATTTCTTTGGCAAATGTTTTGACGCAATGGAGGTAGATGCTTTAAATTCCTCACA
  CCCTGTGTCTACACCTGTGGAAAATCCTGCTCAGATCCGGGAGATGTTTGATGATGTTTC
  TTATGATAAGGGAGCTTGTATTCTGAATATGCTAAGGGAGTATCTTAGTGCTGACGCATT
  TAAAAGTGGTATTGTACAGTATCTCCAGAAGCATAGCTATAAAAATACAAAAAACGAGGA
  CCTGTGGGATAGTATGGCAAGTATTTGCCCTACAGATGGTGTAAAAGGGATGGATGGCTT
  TTGCTCTAGAAGTCAACATTCATCTTCATCCTCACATTGGCATCAGGAAGGGGTGGATGT
  GAAAACCATGATGAACACTTGGACACTGCAGAAGGGTTTTCCCCTAATAACCATCACAGT
  GAGGGGGAGGAATGTACACATGAAGCAAGAGCACTACATGAAGGGCTCTGACGGCGCCCC
  GGACACTGGGTACCTGTGGCATGTTCCATTGACATTCATCACCAGCAAATCCGACATGGT
  CCATCGATTTTTGCTAAAAACAAAAACAGATGTGCTCATCCTCCCAGAAGAGGTGGAATG
  GATCAAATTTAATGTGGGCATGAATGGCTATTACATTGTGCATTACGAGGATGATGGATG
  GGACTCTTTGACTGGCCTTTTAAAAGGAACACACACAGCAGTCAGCAGTAATGATCGGGC
  GAGTCTCATTAACAATGCATTTCAGCTCGTCAGCATTGGGAAGCTGTCCATTGAAAAGGC
  CTTGGATTTATCCCTGTACTTGAAACATGAAACTGAAATTATGCCCGTGTTTCAAGGTTT
  GAATGAGCTGATTCCTATGTATAAGTTAATGGAGAAAAGAGATATGAATGAAGTGGAAAC
  TCAATTCAAGGCCTTCCTCATCAGGCTGCTAAGGGACCTCATTGATAAGCAGACATGGAC
  AGACGAGGGCTCAGTCTCAGAGCGAATGCTGCGGAGTCAACTACTACTCCTCGCCTGTGT
  GCACAACTATCAGCCGTGCGTACAGAGGGCAGAAGGCTATTTCAGAAAGTGGAAGGAATC
  CAATGGAAACTTGAGCCTGCCTGTCGACGTGACCTTGGCAGTGTTTGCTGTGGGGGCCCA
  GAGCACAGAAGGCTGGGATTTTCTTTATAGTAAATATCAGTTTTCTTTGTCCAGTACTGA
  GAAAAGCCAAATTGAATTTGCCCTCTGCAGAACCCAAAATAAGGAAAAGCTTCAATGGCT
  ACTAGATGAAAGCTTTAAGGGAGATAAAATAAAAACTCAGGAGTTTCCACAAATTCTTAC
  ACTCATTGGCAGGAACCCAGTAGGATACCCACTGGCCTGGCAATTTCTGAGGAAAAACTG
  GAACAAACTTGTACAAAAGTTTGAACTTGGCTCATCTTCCATAGCCCACATGGTAATGGG
  TACAACAAATCAATTCTCCACAAGAACACGGCTTGAAGAGGTAAAAGGATTCTTCAGCTC
  TTTGAAAGAAAATGGTTCTCAGCTCCGTTGTGTCCAACAGACAATTGAAACCATTGAAGA
  AAACATCGGTTGGATGGATAAGAATTTTGATAAAATCAGAGTGTGGCTGCAAAGTGAAAA
  GCTTGAACGTATGTAAAAATTCCTCCCTTGCCAGGTTCCTGTTATCTCTAATCACCAACA
  TTTTGTTGAGTGTATTTTCAAACTAGAGATGGCTGTTTTGGCTCCAACTGGAGATACTTT
  TTTCCCTTCAACTCATTTTTTGACTATCCCTGTGAAAAGAATAGCTGTTAGTTTTTCATG
  AATGGGCTATCGCTACCATGTGTTTTGTTCATCACAGGTGTTGCCCTGCAACGTAAACCC
  AAGTGTTGGGTTCCCTGCCACAGAAGAATAAAGTACCTTATTCTTCTCATTTTATAGTTT
  ATGCTTAAGCACCCGTGTCCAAAACCCTGTACCCCATGTTTATCATTCATAAACTGTTTC
  ATCAGCCAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001040458
• ORF Size: 2826 bp
• Insert Size: 3300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001040458.1.

Reference Data

• RefSeq: NM_001040458.1, NP_001035548.1
• RefSeq Size: 5085
• RefSeq ORF: 2826
• Locus ID: 51752
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.