LTBP4 (NM_001042545) Human Untagged Clone

CAT#: SC311429

LTBP4 (untagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LTBP4
• Synonyms: ARCL1C; LTBP-4; LTBP4L; LTBP4S
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC311429 sequence for NM_001042545 edited (data generated by NextGen Sequencing)
  
  
  ATGGCGGGCGGCGTGCGGCTGCTCTGGGTGTCGCTATTGGTGCTGCTGGCGCAGCTAGGGCCGCAGCCTG
  GACTGGGCCGGCTCGGAGAGCGTCTCCGCGTGCGCTTCACCCCGGTCGTGTGCGGCCTGCGCTGCGTCCA
  TGGGCCGACCGGCTCCCGCTGTACCCCGACCTGCGCGCCCCGCAACGCCACCAGCGTGGACAGCGGCGCT
  CCCGGCGGGGCGGCCCCGGGGGGACCCGGCTTCCGCGCCTTCCTGTGTCCCTTGATCTGTCACAATGGCG
  GTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGTTGCACTC
  CTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCC
  AACCACCGCGACGACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGT
  CGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCG
  GGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
  GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCC
  CGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTG
  TCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGC
  TTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCGCGACTGGCGGGCGCTGCCAGCACGGCG
  AGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAG
  CAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGC
  TGTTCGCTGCCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGG
  GCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGG
  TTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGGAGCCACCCCGAGTGTCA
  CTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGG
  AGCCCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTG
  GACTGGTCCTGAGATTCCTGAATCAGGTCCCTCCTCCGGCATGTGTCAGCGCAACCCCCAGGTCTGCGGC
  CCAGGACGCTGCATTTCCCGGCCCAGCGGCTACACCTGCGCTTGCGACTCTGGCTTCCGGCTCAGCCCCC
  AGGGCACCCGATGCATTGATGTGGACGAATGTCGCCGCGTGCCCCCGCCCTGTGCTCCCGGGCGCTGCGA
  GAACTCACCAGGCAGCTTCCGCTGCGTGTGCGGCCCGGGCTTCCGAGCCGGCCCACGGGCTGCGGAATGC
  CTGGATGTGGACGAGTGCCACCGCGTGCCGCCGCCGTGTGACCTCGGGCGCTGCGAGAACACGCCAGGCA
  GCTTCCTGTGCGTGTGCCCCGCCGGGTACCAGGCTGCACCGCACGGAGCCAGCTGCCAGGATGTGGATGA
  ATGCACCCAGAGCCCAGGCCTGTGTGGCCGAGGGGCCTGCAAGAACCTGCCTGGCTCTTTCCGCTGTGTT
  TGCCCGGCTGGCTTCCGGGGCTCGGCGTGTGAAGAGGATGTGGATGAGTGTGCCCAGGAGCCGCCGCCCT
  GTGGGCCCGGCCGCTGTGACAACACGGCAGGCTCCTTTCACTGTGCCTGCCCTGCTGGCTTCCGCTCCCG
  AGGGCCCGGGGCCCCCTGCCAAGATGTGGATGAGTGTGCCCGAAGCCCCCCACCCTGCACCTACGGCCGG
  TGTGAGAACACAGAAGGCAGCTTCCAGTGTGTCTGCCCCATGGGCTTCCAACCCAACACTGCTGGCTCCG
  AGTGCGAGGATGTGGATGAGTGTGAGAACCACCTCGCATGCCCTGGGCAGGAGTGTGTGAACTCGCCCGG
  CTCCTTCCAGTGCAGGACCTGTCCTTCTGGCCACCACCTGCACCGTGGCAGATGCACTGATGTGGACGAA
  TGCAGTTCGGGTGCCCCTCCCTGTGGTCCCCACGGCCACTGCACTAACACCGAAGGCTCCTTCCGCTGCA
  GCTGCGCGCCAGGCTACCGGGCGCCGTCGGGTCGGCCCGGGCCCTGCGCAGACGTGAACGAGTGCCTGGA
  GGGCGATTTCTGCTTCCCTCACGGCGAGTGCCTCAACACTGACGGCTCCTTTGCCTGTACTTGTGCCCCT
  GGCTACCGACCCGGACCCCGCGGAGCCTCTTGCCTCGACGTTGACGAGTGCAGCGAGGAGGACCTTTGCC
  AGAGCGGCATCTGTACCAACACCGACGGCTCCTTCGAGTGCATCTGTCCTCCGGGACACCGCGCTGGCCC
  GGACCTCGCCTCCTGCCTCGACGTGGACGAATGTCGCGAGCGAGGCCCAGCCCTGTGCGGGTCGCAGCGC
  TGTGAGAACTCTCCCGGCTCCTACCGCTGTGTCCGGGACTGCGATCCTGGGTACCACGCGGGCCCCGAGG
  GCACCTGTGACGATGTGGATGAGTGCCAAGAATATGGTCCCGAGATTTGTGGAGCCCAGCGTTGTGAGAA
  CACCCCTGGCTCCTACCGCTGCACACCAGCCTGTGACCCTGGCTATCAGCCCACGCCAGGGGGCGGATGC
  CAGGATGTGGACGAATGCCGGAACCGGTCCTTCTGCGGTGCCCACGCCGTGTGCCAGAACCTGCCCGGCT
  CCTTCCAGTGCCTCTGTGACCAGGGTTACGAGGGGGCACGGGATGGGCGTCACTGCGTGGATGTGAACGA
  GTGTGAAACACTACAGGGTGTATGTGGAGCTGCCCTGTGTGAAAATGTCGAAGGCTCCTTCCTCTGTGTC
  TGCCCCAACAGCCCGGAAGAGTTTGACCCCATGACTGGACGCTGTGTTCCCCCACGAACTTCTGCTGGCA
  CGTTCCCAGGCTCGCAGCCCCAGGCACCTGCTAGCCCCGTTCTGCCCGCCAGGCCACCTCCGCCACCCCT
  GCCCCGCCGACCCAGCACACCTAGGCAGGGCCCTGTGGGGAGTGGGCGCCGGGAGTGCTACTTTGACACA
  GCGGCCCCGGATGCATGTGACAACATCCTGGCTCGGAATGTGACATGGCAGGAGTGCTGCTGTACTGTGG
  GTGAGGGCTGGGGCAGCGGCTGCCGCATCCAGCAGTGCCCGGGCACCGAGACAGCTGAGTACCAGTCATT
  GTGCCCTCACGGCCGGGGCTACCTGGCGCCCAGTGGAGACCTGAGCCTCCGGAGAGACGTGGACGAATGT
  CAGCTCTTCCGAGACCAGGTGTGCAAGAGTGGCGTGTGTGTGAACACGGCCCCGGGCTACTCATGCTATT
  GCAGCAACGGCTACTACTACCACACACAGCGGCTGGAGTGCATCGACAATGACGAGTGCGCCGATGAGGA
  ACCGGCCTGTGAGGGCGGCCGCTGTGTCAACACTGTGGGCTCTTATCACTGTACCTGCGAGCCCCCACTG
  GTGCTGGATGGCTCGCAGCGCCGCTGCGTCTCCAACGAGAGCCAGAGCCTCGATGACAATCTGGGAGTGT
  GCTGGCAGGAAGTGGGGGCTGACCTCGTGTGCAGCCACCCTCGGCTGGACCGTCAGGCCACCTACACAGA
  GTGCTGCTGCCTGTATGGAGAGGCCTGGGGCATGGACTGCGCCCTCTGCCCTGCGCAGGACTCAGATGAC
  TTCGAGGCCCTGTGCAATGTGCTACGCCCCCCCGCATATAGCCCCCCGCGACCAGGTGGCTTTGGACTCC
  CCTACGAGTACGGCCCAGACTTAGGTCCACCTTACCAGGGCCTCCCATATGGGCCTGAGTTGTACCCACC
  ACCTGCGCTACCCTACGACCCCTACCCACCGCCACCTGGGCCCTTCGCCCGCCGGGAGGCTCCTTATGGG
  GCACCCCGCTTCGACATGCCAGACTTTGAGGACGATGGTGGCCCCTATGGCGAATCTGAGGCTCCTGCGC
  CACCTGGCCCGGGCACCCGCTGGCCCTATCGGTCCCGGGACACCCGCCGCTCCTTCCCAGAGCCCGAGGA
  GCCTCCTGAAGGTGGAAGCTATGCTGGTTCCCTGGCTGAGCCCTACGAGGAGCTGGAGGCGGAGGAGTGC
  GGGATCCTGGACGGCTGCACCAACGGCCGCTGCGTGCGCGTCCCCGAAGGCTTCACCTGCCGTTGCTTCG
  ACGGCTACCGCCTGGACATGACCCGCATGGCCTGCGTTGACATCAACGAGTGTGATGAGGCCGAGGCTGC
  CTCCCCGCTGTGCGTCAACGCGCGTTGCCTCAACACGGATGGCTCCTTCCGCTGCATCTGCCGCCCGGGA
  TTCGCACCCACGCACCAGCCGCACCACTGTGCGCCCGCACGGCCCCGGGCCTGA
  
  Clone variation with respect to NM_001042545.1
  
• Restriction Sites: Please inquire
• ACCN: NM_001042545
• ORF Size: 4674 bp
• Insert Size: 5000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001042545.1, NP_001036010.1
• RefSeq Size: 4979
• RefSeq ORF: 4674
• Locus ID: 8425
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus compared to isoform a.