XRN1 (NM_001042604) Human Untagged Clone

CAT#: SC311432

XRN1 (untagged)-Human 5'-3' exoribonuclease 1 (XRN1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: XRN1
• Synonyms: SEP1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001042604, the custom clone sequence may differ by one or more nucleotides
  ATGGGAGTCCCCAAGTTTTACAGATGGATCTCAGAGCGGTATCCCTGTCTCAGCGAAGTG
  GTGAAAGAGCATCAGATTCCTGAATTTGACAACTTGTACCTGGATATGAATGGAATTATA
  CATCAGTGCTCCCATCCTAATGATGATGATGTTCACTTTAGAATTTCAGATGATAAAATC
  TTTACTGATATTTTTCACTACCTGGAGGTGTTGTTTCGCATTATTAAACCCAGGAAAGTG
  TTCTTTATGGCTGTAGATGGTGTGGCTCCTCGAGCAAAAATGAACCAGCAGCGTGGGAGG
  CGTTTTAGGTCAGCAAAGGAGGCAGAAGACAAAATTAAAAAGGCAATAGAGAAGGGAGAA
  ACTCTTCCTACAGAGGCCAGATTTGATTCCAACTGTATCACACCAGGAACTGAATTTATG
  GCCAGGTTACATGAACATCTGAAGTATTTTGTAAATATGAAAATTTCCACAGACAAGTCA
  TGGCAAGGAGTTACCATCTACTTCTCAGGCCATGAGACTCCTGGAGAAGGAGAGCATAAA
  ATCATGGAATTTATCAGATCCGAGAAAGCAAAGCCAGATCATGATCCAAACACCAGACAC
  TGTCTTTATGGTTTAGATGCTGACTTGATTATGCTTGGATTAACAAGTCATGAGGCACAT
  TTTTCTCTCTTAAGAGAAGAAGTTCGATTTGGTGGCAAAAAAACACAACGGGTATGTGCT
  CCAGAAGAAACTACATTTCACCTTCTACACTTGTCTTTAATGAGAGAGTATATTGACTAT
  GAGTTTTCAGTATTAAAAGAAAAGATCACATTTAAATATGATATTGAAAGGATAATAGAT
  GATTGGATTTTGATGGGGTTTCTTGTTGGTAATGATTTTATCCCTCATCTACCTCATTTA
  CATATTAATCATGATGCACTGCCTCTTCTTTATGGAACATATGTTACCATCCTGCCAGAA
  CTTGGGGGTTATATTAATGAAAGTGGGCACCTCAACTTACCTCGATTTGAGAAATACCTT
  GTGAAACTATCAGATTTTGATCGGGAGCACTTCAGTGAAGTTTTTGTGGACCTAAAATGG
  TTTGAAAGCAAAGTTGGTAACAAGTACCTCAATGAAGCAGCAGGTGTCGCAGCAGAAGAA
  GCCAGGAACTACAAGGAAAAGAAAAAGTTAAAGGGCCAGGAAAATTCTCTGTGTTGGACT
  GCTTTAGACAAAAATGAAGGCGAAATGATAACTTCTAAGGATAATTTAGAAGATGAGACT
  GAAGATGATGACCTATTTGAAACTGAGTTTAGACAATATAAAAGAACATATTACATGACG
  AAGATGGGGGTTGACGTAGTATCTGATGACTTTCTGGCTGATCAAGCTGCATGTTATGTT
  CAGGCAATACAGTGGATTTTGCACTATTACTATCATGGAGTTCAGTCCTGGAGCTGGTAT
  TATCCTTATCATTATGCACCTTTCCTGTCTGATATACACAACATCAGTACACTCAAAATC
  CATTTTGAACTAGGAAAACCTTTTAAGCCATTTGAACAGCTTCTTGCTGTACTTCCAGCA
  GCCAGCAAAAATTTACTTCCTGCATGCTACCAGCATTTGATGACCAATGAAGACTCACCA
  ATTATAGAATATTACCCACCTGATTTTAAAACTGACCTAAATGGGAAACAACAGGAATGG
  GAAGCTGTGGTGTTAATCCCTTTTATTGATGAGAAGCGATTATTGGAAGCCATGGAGACA
  TGTAACCACTCCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATAGTGAGTGCCTAATG
  TGCTGGTATGATAGAGACACAGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCT
  GCCATAGAACGATGTTGTACAAGGTATAAAATAATATCCTTAGATGCTTGGCGTGTAGAC
  ATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCATTATATTTCTGTGGATTTCCT
  ACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCAAGTATTCCAG
  CAAAGCAGTCGTGGAGAAAACATGATGTTGGAAATCTTAGTGGATGCAGAATCAGATGAA
  CTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCTTTGTTAATTGGCCT
  CACCTTGAGGAAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAA
  GAACCTCCAGGAACACAGAAGCTTTATTCAGGAAGAACTGCCCCACCATCTAAAGTGGTT
  CATCTTGGAGATAAAGAACAATCTAACTGGGCAAAAGAAGTACAAGGAATTTCAGAACAC
  TACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTGCAGTTGTGTATGCTCAGTTA
  CTCACAGGTCGTAAATATCAAATAAATCAAAATGGTGAAGTTCGTCTAGAGAAACAGTGG
  TCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACATCCGAGCTTTCGAC
  TCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTT
  ATGCTGGGAACTCCCTATTATGGCTGCACTGGAGAAGTTCAGGATTCAGGTGATGTGATT
  ACAGAAGGTAGGATTCGTGTGATTTTCAGCATTCCATGTGAACCCAATCTTGATGCTTTA
  ATACAGAACCAGCATAAATATTCTATAAAGTACAACCCAGGATATGTGTTGGCCAGTCGC
  CTTGGAGTGAGTGGATACCTTGTTTCAAGGTTTACAGGAAGTATTTTTATTGGAAGAGGA
  TCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAAATCTCAAATTCAAC
  AAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCA
  TCTGCAGCAGAACAACTTCTGGCAGAGTACTTAGAGAGAGCTCCAGAACTATTTAGTTAT
  ATAGCCAAAAATAGCCAAGAGGATGTGTTCTATGAAGATGACATTTGGCCTGGAGAAAAT
  GAGAATGGTGCTGAAAAAGTTCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGT
  ACTTTATCTCGTTCTTCTTGTGATTTACAAATTCTGGATGCAGCTATTGTTGAGAAAATT
  GAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATAAGAAGGTGCGAGTAACAGTG
  AAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCCTGATCGGGAT
  GCAGAATTTTGTCTTTTTGACCGTGTTGTAAATGTGAGAGAAAACTTCTCAGTTCCAGTT
  GGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAGCCGATGTACTATTT
  GAAGTATTATTTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGA
  GGTTATCGACTGCCAACAAGTGCCTTGGTGAACCTTTCTCATGGGAGTCGCTCTGAAACT
  GGAAATCAGAAGTTGACAGCCATCGTAAAACCACAACCAGCTGTACATCAACATAGCTCA
  AGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACCATTCCCCTCAATCACTTTTT
  GTTCCTACTCAAGTACCTACTAAAGATGATGATGAATTCTGCAACATTTGGCAGTCCTTA
  CAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGAAGGGTGCAGTTCTA
  CCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTT
  AAATATCAGCAAAGAAAACATGACCCTCACAGAAAATTTAAAGAAGAGTGTAAGAGTCCT
  AAAGCTGAGTGTTGGTCCCAAAAAATGTCCAATAAGCAGCCTAACTCTGGAATTGAGAAC
  TTTTTAGCATCTTTGAATATCTCCAAAGAAAATGAAGTACAGTCATCTCATCATGGGGAG
  CCTCCAAGTGAAGAGCATTTGTCACCACAGTCATTTGCCATGGGAACACGGATGCTTAAA
  GAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGAATGAAATCAAACAGATT
  GCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAGCCT
  AAACAAAATAAGAAATTAGCATCTTATATGAACAAGCCTCACAGTGCTAATGAGTACCAT
  AATGTTCAGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCCAGATCCCTCCTGTATCC
  ACACCAGTAACTGAACTTTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTC
  TCCTTTCTTAGGATGCCACAGACAATGACCGTTTGCCAAGTAAAATTATCTAATGGCTTA
  CTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAGCCAAAGAGAAAGCTGCACTTTTT
  GCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTCACAAGTATTTGCA
  AATTATCCTTCAGCTGTACCACCTGGAACCATTCCTCCAGCCTTTCCCCCACCTACTGCT
  AATATAATGCCTTCGTCGTCTCATCTCTTTGGCTCAATGCCATGGGGACCATCGGTGCCA
  GTTCCTGGGAAGCCCTTCCATCATACTTTATATTCTGGGACCATGCCCATGGCTGGGGGA
  ATACCAGGGGGTGTGCACAATCAGTTTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCA
  AACAAAAAGAACTTTGAGAATAAGGAAGCCCAGAGTTCTCAAGCCACTCCAGTTCAGACT
  AGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTCCACGGGAGAGCTCATCAGCTTCT
  TTGAAGTCCTCTCCGATTGCTCAACCTGCATCTTCTTTTCAAGTTGAAACTGCCTCTCAA
  GGCCATAGTATATCTCACCATAAGTCAACACCAATCTCTTCTTCAAGAAGAAAATCAAGA
  AAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTGAGTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001042604
• ORF Size: 5082 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001042604.1, NP_001036069.1
• RefSeq Size: 10053
• RefSeq ORF: 5082
• Locus ID: 54464
• Protein Pathways: RNA degradation
• Gene Summary: This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]