SEC24B (NM_001042734) Human Untagged Clone

CAT#: SC311500

SEC24B (untagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEC24B
• Synonyms: SEC24
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001042734, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGGCCCCCGCCGGGTCCTCTCACCCGGCCGCCAGCGCCCGGATCCCGCCCAAGTTCGGCGGAGCGG
  CCGTCTCAGGAGCCGCAGCGCCCGCGGGCCCGGGTGCGGGCCCGGCGCCGCACCAGCAGAACGGTCCAGC
  CCAGAATCAAATGCAGGTTCCATCTGGATATGGATTGCATCATCAAAACTATATTGCTCCCTCAGGACAT
  TACTCTCAAGGACCTGGGAAAATGACCTCATTGCCATTGGATACCCAGTGTGGTGATTACTACTCTGCTC
  TCTATACAGTACCAACACAAAATGTGACTCCTAACACAGTGAACCAGCAACCAGGAGCACAGCAGTTGTA
  CAGCAGGGGTCCTCCTGCCCCTCATATTGTGGGATCCACTCTAGGATCTTTCCAAGGTGCTGCATCGTCA
  GCATCCCATTTGCATACGAGTGCCTCCCAACCATACTCCTCTTTTGTGAATCACTACAATAGTCCAGCCA
  TGTACTCTGCCAGCTCTTCTGTTGCGTCTCAGGGATTTCCCTCTACTTGTGGTCATTATGCTATGTCAAC
  TGTTTCTAATGCCGCGTATCCTAGTGTTTCATATCCCTCTCTGCCTGCTGGTGATACATATGGGCAAATG
  TTTACCTCACAGAATGCTCCGACTGTTAGGCCAGTTAAAGATAATTCATTCTCTGGTCAAAATACAGCTA
  TCAGCCATCCATCGCCACTTCCACCTCTACCATCACAACAGCACCACCAGCAGCAAAGTCTTTCAGGATA
  CAGTACTCTAACGTGGTCATCTCCAGGCCTTCCATCGACTCAAGACAATCTCATCCGAAACCACACAGGA
  TCCCTGGCTGTAGCGAACAACAACCCAACCATTACTGTTGCAGATTCTTTATCCTGTCCTGTTATGCAAA
  ATGTTCAGCCTCCCAAGTCCAGCCCAGTGGTATCCACTGTTTTATCAGGATCCTCAGGATCCTCATCAAC
  AAGAACACCTCCCACTGCAAATCACCCAGTTGAGCCTGTGACCTCAGTTACACAGCCATCAGAGCTATTA
  CAACAAAAAGGTGTTGACAGCTCTTCTACCACAAGCAGTGCTTCTCCAATGCCCAACAGTTATGATGCCC
  TGGAAGGAGGCAGTTACCCAGATATGCTTTCTTCATCAGCAAGCAGTCCTGCTCCTGATCCCGCCCCTGA
  ACCTGATCCTGCTTCTGCTCCAGCTCCAGCTTCAGCTCCAGCTCCTGTCGTCCCTCAGCCTTCAAAAATG
  GCTAAGCCTTTTGGCTATGGCTATCCAACACTTCAGCCTGGTTATCAGAATGCTACAGCACCACTTATTT
  CTGGAGTACAGCCCAGTAACCCGGTATATTCTGGATTCCAGCAGTATCCTCAACAGTATCCTGGTGTGAA
  CCAGCTATCCTCCAGTATAGGAGGATTGAGTCTTCAGAGTTCTCCACAACCAGAAAGCCTGAGACCTGTA
  AACCTTACTCAGGAGAGGAATATTTTACCTATGACTCCTGTTTGGGCTCCTGTACCTAACTTGAATGCAG
  ACCTCAAAAAATTAAACTGTAGCCCAGATTCATTTCGGTGTACTTTGACAAATATTCCACAGACACAGGC
  TTTACTGAATAAAGCTAAGCTTCCTTTAGGATTGTTGTTACATCCCTTCAGAGACCTAACGCAATTACCA
  GTGATAACATCAAATACCATTGTGAGGTGCCGATCCTGTCGAACGTATATTAACCCCTTTGTATCCTTCA
  TTGATCAACGTAGATGGAAATGCAATTTGTGCTATAGAGTAAACGATGTTCCTGAAGAATTTATGTATAA
  CCCCCTTACCCGATCTTATGGAGAGCCTCATAAACGACCAGAAGTTCAGAATTCAACTGTGGAGTTCATT
  GCTTCTTCAGATTACATGCTGCGTCCTCCTCAACCTGCAGTTTACTTGTTTGTTTTAGATGTGTCTCATA
  ATGCAGTGGAAGCTGGATATTTGACAATTTTGTGCCAGTCACTCCTAGAAAATCTAGACAAGCTTCCTGG
  AGATTCACGAACAAGAATAGGATTCATGACCTTTGATAGCACTATTCATTTCTACAATTTACAAGAAGGA
  TTATCACAGCCTCAAATGTTGATTGTGTCTGATATAGATGATGTTTTTCTACCTACACCGGATAGTTTAC
  TTGTGAATCTATATGAAAGTAAAGAGCTTATAAAAGACTTACTGAATGCATTACCAAACATGTTCACCAA
  TACAAGAGAAACACACAGTGCCCTTGGTCCTGCACTTCAGGCTGCCTTTAAATTAATGTCTCCAACAGGT
  GGCCGTGTGTCTGTATTTCAGACACAGTTACCTTCCTTGGGTGCAGGACTTCTGCAATCCAGAGAAGATC
  CTAATCAGAGATCAAGTACAAAGGTGGTACAACATCTTGGCCCTGCAACTGATTTTTATAAGAAACTTGC
  ATTAGATTGCTCGGGACAGCAAACTGCAGTGGATTTGTTCCTTTTAAGTTCACAGTATTCTGATCTTGCT
  TCTCTAGCTTGCATGTCCAAGTATTCTGCAGGGTGCATCTATTATTATCCATCATTCCACTATACTCACA
  ATCCTTCACAAGCAGAAAAGTTACAAAAAGACCTAAAACGGTATCTCACAAGAAAAATTGGGTTTGAAGC
  TGTTATGAGAATAAGGTGTACTAAAGGTCTTTCAATGCACACTTTTCACGGTAACTTCTTTGTCCGTTCT
  ACTGATTTGTTATCCCTTGCCAACATCAATCCTGATGCTGGATTTGCGGTGCAGTTGTCAATTGAAGAAA
  GTTTAACAGATACTTCCTTAGTATGTTTTCAAACAGCCCTATTATATACATCAAGCAAAGGTGAGCGGAG
  AATTAGAGTACATACACTTTGTTTGCCAGTGGTAAGTTCACTAGCAGATGTATATGCGGGAGTGGATGTA
  CAAGCTGCCATCTGCCTTCTGGCAAACATGGCTGTGGATCGGTCCGTTTCATCAAGTCTGTCAGATGCAA
  GAGATGCCTTAGTGAATGCTGTAGTGGACTCATTGTCTGCATATGGCTCAACTGTCTCAAATTTACAGCA
  CTCTGCATTGATGGCGCCCAGCTCCCTCAAGTTGTTTCCTCTCTATGTTTTGGCCCTTCTCAAACAGAAA
  GCATTTAGAACGGGTACAAGCACACGGCTGGATGATCGTGTATATGCCATGTGTCAGATAAAGTCTCAGC
  CACTTGTTCATCTAATGAAAATGATTCATCCCAACTTATACAGGATAGACAGATTGACAGATGAGGGTGC
  AGTACATGTTAATGACAGGATTGTACCACAGCCACCTCTTCAAAAATTGTCTGCAGAGAAGCTGACAAGA
  GAAGGTGCTTTCCTTATGGACTGTGGCTCTGTTTTTTACATTTGGGTTGGGAAAGGCTGTGACAATAACT
  TCATAGAGGATGTGCTTGGATATACTAATTTTGCATCAATACCACAGAAAATGACACATCTTCCAGAGCT
  AGATACACTTTCATCAGAAAGAGCCAGATCCTTCATAACTTGGCTTAGAGACAGCAGACCATTAAGTCCA
  ATCCTTCACATAGTAAAAGATGAGAGTCCTGCCAAAGCAGAATTTTTTCAGCATTTGATTGAAGACCGGA
  CAGAGGCTGCATTTTCTTACTATGAATTTTTGCTTCATGTTCAGCAGCAGATTTGTAAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001042734
• ORF Size: 3702 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001042734.3, NP_001036199.1
• RefSeq Size: 4651
• RefSeq ORF: 3702
• Locus ID: 10427
• Gene Summary: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (2) lacks two in-frame exons in the 5' and central coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (b) is shorter, compared to isoform c.