RTN3 (NM_201429) Human Untagged Clone

CAT#: SC312668

RTN3 (untagged)-Human reticulon 3 (RTN3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RTN3
• Synonyms: ASYIP; HAP; NSPL2; NSPLII; RTN3-A1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_201429 edited
  ATGGCGGAGCCGTCGGCGGCCACTCAGTCCCATTCCATCTCCTCGTCGTCCTTCGGAGCC
  GAGCCGTCCGCGCCCGGCGGCGGCGGGAGCCCAGGAGCCTGCCCCGCCCTGGGGACGAAG
  AGCTGCAGCTCCTCCTGTGCGGATTCCTTTGTTTCTTCCTCTTCCTCTCAGCCTGTATCT
  CTATTTTCGACCTCACAAGTGCACGATCTGATTTTCTGGAGAGATGTGAAGAAGACTGGG
  TTTGTCTTTGGCACCACGCTGATCATGCTGCTTTCCCTGGCAGCTTTCAGTGTCATCAGT
  GTGGTTTCTTACCTCATCCTGGCTCTTCTCTCTGTCACCATCAGCTTCAGGATCTACAAG
  TCCGTCATCCAAGCTGTACAGAAGTCAGAAGAAGGCCATCCATTCAAAGCCTACCTGGAC
  GTAGACATTACTCTGTCCTCAGAAGCTTTCCATAATTACATGAATGCTGCCATGGTGCAC
  ATCAACAGGGCCCTGAAACTCATTATTCGTCTCTTTCTGGTAGAAGATCTGGTTGACTCC
  TTGAAGCTGGCTGTCTTCATGTGGCTGATGACCTATGTTGGTGCTGTTTTTAACGGAATC
  ACCCTTCTAATTCTTGCTGAACTGCTCATTTTCAGTGTCCCGATTGTCTATGAGAAGTAC
  AAGACCCAGATTGATCACTATGTTGGCATCGCCCGAGATCAGACCAAGTCAATTGTTGAA
  AAGATCCAAGCAAAACTCCCTGGAATCGCCAAAAAAAAGGCAGAATAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_201429 unedited
  TGAACCCCACTTTACTATAGGCGGCCGCGCAATTCGCACGAGGGTCCTCGGAGCAGGCGG
  AGTAAAGGGACTTGAGCGAGCCAGTTGCCGGATTATTCTATTTCCCCTCCCTCTCTCCCG
  CCCCGTATCTCTTTTCACCCTTCTCCCACCCTCGCTCGCGTAGCCATGGCGGAGCCGTCG
  GCGGCCACTCAGTCCCATTCCATCTCCTCGTCGTCCTTCGGAGCCGAGCCGTCCGCGCCC
  GGCGGCGGCGGGAGCCCAGGAGCCTGCCCCGCCCTGGGGACGAAGAGCTGCAGCTCCTCC
  TGTGCGGATTCCTTTGTTTCTTCCTCTTCCTCTCAGCCTGTATCTCTATTTTCGACCTCA
  CAAGTGCACGATCTGATTTTCTGGAGAGATGTGAAGAAGACTGGGTTTGTCTTTGGCACC
  ACGCTGATCATGCTGCTTTCCCTGGCAGCTTTCAGTGTCATCAGTGTGGTTTCTTACCTC
  ATCCTGGCTCTTCTCTCTGTCACCATCAGCTTCAGGATCTACAAGTCCGTCATCCAAGCT
  GTACAGAAGTCAGAAGAAGGCCATCCATTCAAAGCCTACCTGGACGTAGACATTACTCTG
  TCCTCAGAAGCTTTCCATAATTACATGAATGCTGCCATGGTGCACATCAACAGGGGCCCT
  GAAACTCATTATTCGTCTCTTTCTGGTAGAAGATCTGGTTGACTCCTTGAAGCTGGCTGT
  CTTCATGTGGCTGATGAACCTATGTGGTGCTGTTNTTAACGGAATCACCCTTCTAATNCT
  TGCTGAACTGCTCATTNTCAGTGTCCCGATTGTCTATGAAAGTACAAGACCAGATTGATC
  ACTATGTTGCATCGCCCGAGACAGACCAGTCATTGTTGAAAAGACCAAGCAAACTC
  
• Restriction Sites: Please inquire
• ACCN: NM_201429
• ORF Size: 768 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_201429.1.

Reference Data

• RefSeq: NM_201429.1, NP_958832.1
• RefSeq Size: 2668
• RefSeq ORF: 768
• Locus ID: 10313
• Protein Families: Transmembrane
• Gene Summary: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (3) includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (c) is longer than isoform a.