TMP21 (TMED10) (BC016287) Human Untagged Clone
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | TMED10 |
Synonyms | ZNF252 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for BC016287, the custom clone sequence may differ by one or more nucleotides
|
Restriction Sites | Please inquire |
ACCN | BC016287 |
ORF Size | 1580 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | BC016287.1 |
RefSeq Size | 1580 |
RefSeq ORF | 1580 |
Locus ID | 10972 |
Domains | zf-C2H2 |
Protein Families | Transmembrane |
Gene Summary | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008] |
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