ALP (PDLIM3) (NM_014476) Human Untagged Clone

CAT#: SC313141

PDLIM3 (untagged)-Human PDZ and LIM domain 3 (PDLIM3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDLIM3
• Synonyms: ALP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_014476 edited
  ATGCCCCAGACGGTGATCCTCCCGGGCCCTGCGCCCTGGGGCTTCAGGCTCTCAGGGGGC
  ATAGACTTCAACCAGCCTTTGGTCATCACCAGGATTACACCAGGAAGCAAGGCGGCAGCT
  GCCAACCTGTGTCCTGGAGATGTCATCCTGGCTATTGACGGCTTTGGGACAGAGTCCATG
  ACTCATGCTGATGCGCAGGACAGGATTAAAGCAGCAGCTCACCAGCTGTGTCTCAAAATT
  GACAGGGGAGAAACTCACTTATGGTCTCCACAAGTATCTGAAGATGGGAAAGCCCATCCT
  TTCAAAATCAACTTAGAATCAGAACCACAGGACGGGAACTACTTTGAACACAAGCATAAT
  ATTCGGCCCAAACCTTTCGTGATCCCGGGCCGAAGCAGTGGATGCAGCACTCCCTCCGGG
  ATTGACTGTGGCAGTGGACGCAGCACCCCTTCTTCTGTCAGTACTGTTAGTACCATTTGC
  CCAGGTGACTTGAAAGTTGCGGCTAAGCTGGCCCCTAACATTCCTTTGGAAATGGAACTT
  CCTGGTGTGAAGATTGTACATGCTCAGTTTAATACACCTATGCAGTTGTACTCAGATGAC
  AATATTATGGAAACACTCCAGGGTCAGGTTTCAACAGCCCTAGGGGAAACACCTTTGATG
  AGCGAGCCCACAGCCTCGGTGCCCCCCGAGTCGGACGTGTACCGGATGCTCCACGACAAT
  CGGAATGAGCCCACACAGCCTCGCCAGTCGGGCTCCTTCAGAGTGCTCCAGGGAATGGTG
  GACGATGGCTCTGATGACCGTCCGGCTGGAACGCGGAGTGTGAGAGCTCCGGTGACGAAA
  GTCCATGGCGGTTCAGGCGGGGCACAGAGGATGCCGCTCTGTGACAAATGTGGGAGTGGC
  ATAGTTGGTGCTGTGGTGAAGGCGCGGGATAAGTACCGGCACCCTGAGTGCTTCGTGTGT
  GCCGACTGCAACCTCAACCTCAAGCAAAAGGGCTACTTCTTCATAGAAGGGGAGCTGTAC
  TGCGAAACCCACGCAAGAGCCCGCACAAAGCCCCCAGAGGGCTATGACACGGTCACTCTG
  TATCCCAAAGCTTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014476 unedited
  GACCATATGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGTGGCTGC
  CCTGCGCGGGGACACTCAGAGCCCGGTGGGCGGGAGGAAGGCGGCATGCCCCAGACGGTG
  ATCCTCCCGGGCCCTGCGCCCTGGGGCTTCAGGCTCTCAGGGGGCATAGACTTCAACCAG
  CCTTTGGTCATCACCAGGATTACACCAGGAAGCAAGGCGGCAGCTGCCAACCTGTGTCCT
  GGAGATGTCATCCTGGCTATTGACGGCTTTGGGACAGAGTCCATGACTCATGCTGATGCG
  CAGGACAGGATTAAAGCAGCAGCTCACCAGCTGTGTCTCAAAATTGACAGGGGAGAAACT
  CACTTATGGTCTCCACAAGTATCTGAAGATGGGAAAGCCCATCCTTTCAAAATCAACTTA
  GAATCAGAACCACAGGACGGGAACTACTTTGAACACAAGCATAATATTCGGCCCAAACCT
  TTCGTGATCCCGGGCCGAAGCAGTGGATGCAGCACTCCCTCCGGGATTGACTGTGGCAGT
  GGACGCAGCACCCCTTCTTCTGTCAGTACTGTTAGTACCATTTGCCCAGGTGACTTGAAA
  GTTGCGGCTAAGCTGGCCCCTAACATTCCTTTGGAAATGGAACTTCCTGGTGTGAAGATT
  GTACATGCTCAGTTTAATACACCTATGCAGTTGTACTCAGATGACAATATTATGGAAACA
  CTCCAGGGTCAGTTTCAACAGCCCTAGGGGAAACACCTTTGATGAGCGAGCCCACAGCCT
  CGGTGCCCCCCGAGTCGGACGTGTACCGGATGCTCCACGACATCGGAATGAGCCCACACA
  GCCTCCGCCAGTCGGGCTCTTCAAGTGCTCAGGAATGGTGGACGATGGCTCTGATGACCG
  TCCGGCTGGAACGGCGGGAGTGTGGGAGAGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014476 unedited
  TGGCAATGCACTTCAGGGCCGGAGAGCACTTGGGGAGGGGTCACAGGGATGCCACCCGGG
  ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT
  TTTTTGTTTTTATTTTTTAAATCTTTTATGTATTTATTATGTTTGTTGCATCGAGTGGCA
  TAATTGTTTGAATACAAAACTAAAGAAATTCAGGGAATTTCTCCCTAACATGCACTGTAA
  TAGTTAAAACACATACAGACAACTGCAGATTATGTTAGAATACAAGATTGTTATTTGCTA
  TTTACCACAATTGCAAAATCAACTTGTCAAGGAAAGACAATTAGAGTCCTTCAAATATCT
  TGATGTTTATGTGTTTGATGGCTGTAATATACATGTAAATTGTGGAGTATGACATACAAA
  AAATTATTGCTTTAAATATCATTATTGCTAGCCCCAAAAAGAGTTGCAAAACATAGCTAA
  GTGTATGTTTTTTTCACATAGCAGGCATTTGCCTCCCATTCCTTTTCCTCAATAAACAAT
  AGGATAAAGGTCTAAAGCCTTGACTTTAGATTTGGAGTTGACAATCTGCACAATCCTTCT
  GCCCAAAGCCATGAATGTCTTCTCGTGTAAGTGCGCGTGGGTGGGTGCGTGCGTGCGTGC
  CACGCCTGCAGAGACTTAAGCTTTGGGATACAGAGTGACCGTGTCATAGCCCTCTGGGGG
  CTTTGTGCGGGCTCTTGCGTGGGTTTCGCAGTACAGCTCCCCTTCTATGAAGAAGTAGCC
  CTTTTGCTTGAGTTGAGTTGCAGTCGCACACACGAAGCACTCAGGTGCCGGTACTTATCC
  CGCGCCTTCACCACAGCACCAACTATGCCACTCCCCACA
  
• Restriction Sites: Please inquire
• ACCN: NM_014476
• ORF Size: 1095 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_014476.1, NP_055291.1
• RefSeq Size: 1722
• RefSeq ORF: 1095
• Locus ID: 27295
• Domains: PDZ, LIM, ZM
• Gene Summary: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.