BMP11 (GDF11) (NM_005811) Human Untagged Clone

CAT#: SC313332

GDF11 (untagged)-Human growth differentiation factor 11 (GDF11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GDF11
• Synonyms: BMP-11; BMP11
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_005811 edited
  ATGGTGCTCGCGGCCCCGCTGCTGCTGGGCTTCCTGCTCCTCGCCCTGGAGCTGCGGCCC
  CGGGGGGAGGCGGCCGAGGGCCCCGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCAGCG
  GCGGGGGTCGGGGGGGAGCGCTCCAGCCGGCCAGCCCCGTCCGTGGCGCCCGAGCCGGAC
  GGCTGCCCCGTGTGCGTTTGGCGGCAGCACAGCCGCGAGCTGCGCCTAGAGAGCATCAAG
  TCGCAGATCTTGAGCAAACTGCGGCTCAAGGAGGCGCCCAACATCAGCCGCGAGGTGGTG
  AAGCAGCTGCTGCCCAAGGCGCCGCCGCTGCAGCAGATCCTGGACCTACACGACTTCCAG
  GGCGACGCGCTGCAGCCCGAGGACTTCCTGGAGGAGGACGAGTACCACGCCACCACCGAG
  ACCGTCATTAGCATGGCCCAGGAGACGGACCCAGCAGTACAGACAGATGGCAGCCCTCTC
  TGCTGCCATTTTCACTTCAGCCCCAAGGTGATGTTCACAAAGGTACTGAAGGCCCAGCTG
  TGGGTGTACCTACGGCCTGTACCCCGCCCAGCCACAGTCTACCTGCAGATCTTGCGACTA
  AAACCCCTAACTGGGGAAGGGACCGCAGGGGGAGGGGGCGGAGGCCGGCGTCACATCCGT
  ATCCGCTCACTGAAGATTGAGCTGCACTCACGCTCAGGCCATTGGCAGAGCATCGACTTC
  AAGCAAGTGCTACACAGCTGGTTCCGCCAGCCACAGAGCAACTGGGGCATCGAGATCAAC
  GCCTTTGATCCCAGTGGCACAGACCTGGCTGTCACCTCCCTGGGGCCGGGAGCCGAGGGG
  CTGCATCCATTCATGGAGCTTCGAGTCCTAGAGAACACAAAACGTTCCCGGCGGAACCTG
  GGTCTGGACTGCGACGAGCACTCAAGCGAGTCCCGCTGCTGCCGATATCCCCTCACAGTG
  GACTTTGAGGCTTTCGGCTGGGACTGGATCATCGCACCTAAGCGCTACAAGGCCAACTAC
  TGCTCCGGCCAGTGCGAGTACATGTTCATGCAAAAATATCCGCATACCCATTTGGTGCAG
  CAGGCCAATCCAAGAGGCTCTGCTGGGCCCTGTTGTACCCCCACCAAGATGTCCCCAATC
  AACATGCTCTACTTCAATGACAAGCAGCAGATTATCTACGGCAAGATCCCTGGCATGGTG
  GTGGATCGCTGTGGCTGCTCTTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005811 unedited
  ATTTGTAATACGACTGCACTATAGGGCGGCCGCGAATTCGCCCTTCGTGCTCTCCAGCAT
  GGTGCTCGCGGCCCCGCTGCTGCTGGGCTTCCTGCTCCTCGCCCTGGAGCTGCGGCCCCG
  GGGGGAGGCGGCCGAGGGCCCCGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCAGCGGC
  GGGGGTCGGGGGGGAGCGCTCCAGCCGGCCAGCCCCGTCCGTGGCGCCCGAGCCGGACGG
  CTGCCCCGTGTGCGTTTGGCGGCAGCACAGCCGCGAGCTGCGCCTAGAGAGCATCAAGTC
  GCAGATCTTGAGCAAACTGCGGCTCAAGGAGGCGCCCAACATCAGCCGCGAGGTGGTGAA
  GCAGCTGCTGCCCAAGGCGCCGCCGCTGCAGCAGATCCTGGACCTACACGACTTCCAGGG
  CGACGCGCTGCAGCCCGAGGACTTCCTGGAGGAGGACGAGTACCACGCCACCACCGAGAC
  CGTCATTAGCATGGCCCAAGAGACGGACCCAGCAGTACAGACAGATGGCAGCCCTCTCTG
  GTGCCATTTCACTTAACCCCCAGGTGATGTCAACAAAGTACTTGAGGCCCACTTGTGGTG
  GTACTACGGCCTGTACCCCGCCAGCCCAGTCTACCTGAAGATTTGCGACTAAACCCCTAA
  TGGGGAAGGACCCANGGGGAGGGCCGAGCCGGCGTCAAATCGATCCGTCATGAAATGACT
  GACTCACCTAGGCATGGAAAACATGACTAAGCAGTGCTACANGTGTTCGCAGCCAAAACA
  TTGGGATTAGATAACCTGTTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005811 unedited
  NNGGTGCCCCCATTGGGNNGATGGCAACTTNCCAGGNCCAGNAAAGCACTGGGGAAGGGT
  CACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGA
  GTCGAGTTTTTTTTTTTTTTTTTTTTTTTTACCCTTTAAGCCTGTTTATTCCCTTCTGTC
  ATACTCACAAGCATTTTTTATCCTCTGTGAAGAGGTTAAGTTACCCACCCACCAAGTCTT
  TGCTCCAGCAGCTTGTAGTGACCCACTTAAGAGCAGCCACAGCGATCCACCACCATGCCA
  GGGATCTTGCCGTAAATAATCTGCTGCTTGTCATTGAAGTAGAGCATGTTGATTGGGGAC
  ATCTTGGTGGGGGTACAACAGGGCCCAGCAGAGCCTCTTGGATTGGCCTGCTGCACCAAA
  TGGGTATGCGGATATTTTTGCATGAACATGTACTCGCACTGGCCGGAGCAGTAGTTGGCC
  TTGTAGCGCTTAGGTGCGATGATCCAGTCCCAGCCGAAAGCCTCAAAGTCCACTGTGAGG
  GGATATCGGCAGCAGCGGGACTCGCTTGAGTGCTCGTCGCAGTCCAGACCCAGGTTCCGC
  CGGGAACGTTTTGTGTTCTCTAGGACTCGAAGCTCCATGAATGGATGCAGCCCCTCGGCT
  CCCGGCCCCAGGGAGGTGACAGCCAGGTCTGTGCCACTGGGATCAAAGGCGTTGATCTCG
  ATGCCCCAGTTGCTCTGTGGCTGGCGGAACCAGCTGTGTAGCACTTGCTTGAAGTCGATG
  CTCTGCCAATGGCCTGAGCGTGAGTGCAGCTCAATCTTCAGTGAGCGGATACCGATGTGA
  CCGCCGCCTNCGCCCCTCCCCCTGNGGTCCCTTTCCCAGTAGGGGTTTTAGTCCCAGAAC
  TGG
  
• Restriction Sites: Please inquire
• ACCN: NM_005811
• ORF Size: 1224 bp
• Insert Size: 1400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_005811.2, NP_005802.1
• RefSeq Size: 1662
• RefSeq ORF: 1224
• Locus ID: 10220
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]