SPRED2 (NM_181784) Human Untagged Clone

CAT#: SC313375

SPRED2 (untagged)-Human sprouty-related, EVH1 domain containing 2 (SPRED2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPRED2
• Synonyms: Spred-2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_181784 edited
  ATGACCGAAGAAACACACCCAGACGATGACAGCTATATTGTGCGTGTCAAGGCTGTGGTT
  ATGACCAGAGATGACTCCAGCGGGGGATGGTTCCCACAGGAAGGAGGCGGGATCAGTCGC
  GTCGGGGTCTGTAAGGTCATGCACCCCGAAGGCAATGGACGAAGCGGCTTTCTCATCCAT
  GGTGAACGACAGAAAGACAAACTGGTGGTATTGGAATGCTATGTAAGAAAGGACTTGGTC
  TACACCAAAGCCAATCCAACGTTTCATCACTGGAAGGTCGATAATAGGAAGTTTGGACTT
  ACTTTCCAAAGCCCTGCTGATGCCCGAGCCTTTGACAGGGGAGTAAGGAAAGCAATCGAA
  GACCTTATAGAAGGTTCAACAACGTCATCTTCCACCATCCATAATGAAGCTGAGCTTGGC
  GATGATGACGTTTTTACAACAGCTACAGACAGTTCTTCTAATTCCTCTCAGAAGAGAGAG
  CAACCTACTCGGACAATCTCCTCTCCCACATCCTGTGAGCACCGGAGGATTTATACCCTG
  GGCCACCTCCACGACTCATACCCCACAGACCACTATCACCTCGATCAGCCGATGCCAAGG
  CCCTACCGCCAGGTGAGCTTCCCGGACGACGACGAGGAGATCGTGCGCATCAACCCCCGG
  GAGAAGATCTGGATGACGGGGTACGAGGATTACCGGCACGCACCCGTCAGGGGCAAGTAC
  CCGGACCCCTCGGAGGACGCGGACTCCTCCTACGTGCGCTTCGCCAAGGGCGAGGTCCCC
  AAGCATGACTACAACTACCCCTACGTGGACTCCTCAGACTTTGGCCTAGGCGAGGACCCC
  AAAGGCCGCGGGGGCAGCGTGATCAAGACGCAGCCCTCCCGGGGCAAGTCGCGGCGGCGG
  AAGGAGGACGGAGAGCGCTCGCGGTGCGTGTACTGCAGGGACATGTTCAACCACGAGGAG
  AACCGCCGGGGCCACTGCCAGGACGCGCCCGACTCCGTGAGAACTTGCATCCGCCGGGTG
  AGCTGCATGTGGTGCGCGGACAGCATGCTCTATCACTGTATGTCGGACCCCGAGGGAGAC
  TATACAGACCCTTGCTCGTGCGATACTAGCGACGAGAAGTTTTGCCTCCGGTGGATGGCT
  CTTATTGCCTTGTCTTTCCTGGCCCCCTGTATGTGCTGTTACCTGCCCCTTCGGGCCTGC
  TACCACTGCGGAGTGATGTGCAGGTGCTGTGGCGGGAAGCACAAAGCGGCCGCGTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_181784
• ORF Size: 1257 bp
• Insert Size: 5000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_181784.1.

Reference Data

• RefSeq: NM_181784.1, NP_861449.1
• RefSeq Size: 4119
• RefSeq ORF: 1257
• Locus ID: 200734
• Protein Pathways: Jak-STAT signaling pathway
• Gene Summary: SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).