PKMYT1 (NM_182687) Human Untagged Clone

CAT#: SC313659

PKMYT1 (untagged)-Human protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PKMYT1
• Synonyms: MYT1; PPP1R126
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182687 edited
  AGGCCCACCATGCTAGAACGGCCTCCTGCACTGGCCATGCCCATGCCCACGGAGGGCACC
  CCGCCACCTCTGAGTGGCACCCCCATCCCAGTCCCAGCCTACTTCCGCCACGCAGAACCT
  GGATTCTCCCTCAAGAGGCCCAGGGGGCTCAGCCGGAGCCTCCCACCTCCGCCCCCTGCC
  AAGGGCAGCATTCCCATCAGCCGCCTCTTCCCTCCTCGGACCCCAGGCTGGCACCAGCTG
  CAGCCCCGGCGGGTGTCATTCCGGGGCGAGGCCTCAGAGACTCTGCAGAGCCCTGGGTAT
  GACCCAAGCCGGCCAGAGTCCTTCTTCCAGCAGAGCTTCCAGAGGCTCAGCCGCCTGGGC
  CATGGCTCCTACGGAGAGGTCTTCAAGGTGCGCTCCAAGGAGGACGGCCGGCTCTATGCG
  GTAAAGCGTTCCATGTCACCATTCCGGGGCCCCAAGGACCGGGCCCGCAAGTTGGCCGAG
  GTGGGCAGCCACGAGAAGGTGGGGCAGCACCCATGCTGCGTGCGGCTGGAGCAGGCCTGG
  GAGGAGGGCGGCATCCTGTACCTGCAGACGGAGCTGTGCGGGCCCAGCCTGCAGCAACAC
  TGTGAGGCCTGGGGTGCCAGCCTGCCTGAGGCCCAGGTCTGGGGCTACCTGCGGGACACG
  CTGCTTGCCCTGGCCCATCTGCACAGCCAGGGCCTGGTGCACCTTGATGTCAAGCCTGCC
  AACATCTTCCTGGGGCCCCGGGGCCGCTGCAAGCTGGGTGACTTCGGACTGCTGGTGGAG
  CTGGGTACAGCAGGAGCTGGTGAGGTCCAGGAGGGAGACCCCCGCTACATGGCCCCCGAG
  CTGCTGCAGGGCTCCTATGGGACAGCAGCGGATGTGTTCAGTCTGGGCCTCACCATCCTG
  GAAGTGGCATGCAACATGGAGCTGCCCCACGGTGGGGAGGGCTGGCAGCAGCTGCGCCAG
  GGCTACCTGCCCCCTGAGTTCACTGCCGGTCTGTCTTCCGAGCTGCGTTCTGTCCTTGTC
  ATGATGCTGGAGCCAGACCCCAAGCTGCGGGCCACGGCCGAGGCCCTGCTGGCACTGCCT
  GTGTTGAGGCAGCCGCGGGCCTGGGGTGTGCTGTGGTGCATGGCAGCGGAGGCCCTGAGC
  CGAGGGTGGGCCCTGTGGCAGGCCCTGCTTGCCCTGCTCTGCTGGCTCTGGCATGGGCTG
  GCTCACCCTGCCAGCTGGCTACAGCCCCTGGGCCCGCCAGCCACCCCGCCTGGCTCACCA
  CCCTGCAGTTTGCTCCTGGACAGCAGCCTCTCCAGCAACTGGGATGACGACAGCCTAGGC
  CCTGGACACCCTCCTTGTCTCGCCTGCCCTCCTGCAGGCCTTCACTCTCCCCTGAGGCTG
  TCCTGGCCCGGACTGTGGGGAGCACCTCCACCCCCCGGAGCAGGTGCACACCCAGGGATG
  CCCTGGACCTAGGGCCTCATGGGCCCAGCTTTCTTGTAC
  
• Restriction Sites: Please inquire
• ACCN: NM_182687
• ORF Size: 1443 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_182687.1.

Reference Data

• RefSeq: NM_182687.1, NP_872629.1
• RefSeq Size: 2159
• RefSeq ORF: 1443
• Locus ID: 9088
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation
• Gene Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.