SESN3 (NM_144665) Human Untagged Clone

CAT#: SC313706

SESN3 (untagged)-Human sestrin 3 (SESN3)


  "NM_144665" in other vectors (6)

Reconstitution Protocol

USD 830.00

5 Days*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SESN3
Synonyms SEST3
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_144665 edited
CCTAGCCTGGCGGGGGCGGGGGTCTGGAAGAGGGGGCGGGTGGAACAACGGGCCGGTGAG
GAGCAGCCGCCGCCGTCTCCGCCGTCGCTGGGGCAGCTGCCGCGGTGGTCGCCTCTGGCA
GTGCCGCTAGCTTTCAGGCAGTCGCCTCTCCTCCCGACATCCCGCCTTGAGGAGGCTGAG
GCGGAATCGCGGCTGGCGGCGGGGGGACGGACCGGCCCTGCAGTGGCCGCAGTGACAGCC
CGGACCCGGCCCTCCGCCCGCTCTCGCCTCGGCGCCCGCAGCCACGATGAACCGGGGCGG
CGGCAGCCCGTCGGCCGCCGCCAACTACCTGCTCTGTACCAACTGCCGGAAAGTGCTGCG
GAAGGATAAAAGAATCAGAGTGTCTCAACCCTTGACAAGAGGACCAAGTGCCTTTATTCC
AGAGAAGGAAGTTGTCCAAGCAAACACAGTGGATGAACGTACTAACTTTCTTGTGGAAGA
ATACTCTACATCCGGTCGTCTGGACAACATCACACAGGTCATGAGTTTACACACTCAGTA
CCTGGAGTCTTTCTTGCGGAGCCAGTTTTACATGTTGCGCATGGATGGTCCCCTTCCTCT
ACCATACAGGCACTATATTGCAATAATGGCTGCAGCTAGACATCAGTGTTCTTACTTAAT
AAACATGCATGTGGATGAATTTTTAAAGACTGGAGGTATTGCTGAGTGGTTGAATGGTTT
GGAATATGTGCCACAAAGACTGAAAAATCTTAATGAAATTAATAAGCTGCTAGCACATCG
ACCTTGGCTGATCACAAAAGAGCACATTCAGAAACTTGTCAAAACTGGAGAAAATAATTG
GTCTCTGCCTGAACTGGTACATGCTGTGGTCCTCCTGGCACATTATCATGCTTTGGCAAG
CTTTGTTTTTGGTAGTGGTATCAATCCAGAGAGAGATCCAGAAATCTCCAATGGATTCAG
GCTAATATCAGTCAACAATTTCTGCGTTTGTGATCTTGCTAATGACAACAACATAGAGAA
TGCATCTCTTTCAGGCAGCAACTTTGGGATTGTGGATTCTCTAAGTGAGCTAGAGGCCTT
AATGGAAAGGATGAAAAGACTTCAAGAAGAAAGGGAAGATGAAGAGGCGTCTCAAGAAGA
AATGAGCACTCGTTTTGAAAAGGAGAAGAAAGAAAGTCTTTTTGTGGTCTCTGGAGATAC
TTTTCATTCATTTCCTCATTCAGATTTTGAGGATGACATGATTATAACATCTGATGTCTC
TCGATATATTGAAGACCCTGGTTTTGGGTATGAAGACTTTGCCAGACGAGGAGAAGAGCA
TTTGCCAACATTCCGAGCTCAGGACTATACCTGGGAAAATCATGGGTTCTCCCTGGTGAA
CAGACTTTATTCTGACATTGGACATCTTCTTGATGAAAAGTTTCGGATGGTCTACAATCT
CACATATAACACTATGGCCACCCATGAGGATGTTGACACAACCATGCTGCGCAGAGCTTT
ATTTAACTATGTTCACTGTATGTTTGGAATCAGGTATGATGACTATGATTATGGAGAAGT
TAATCAATTACTTGAAAGAAGCCTGAAGGTTTACATTAAGACAGTGACCTGCTATCCTGA
GAGAACTACAAAACGCATGTATGATAGTTACTGGCGGCAGTTCAAACACTCAGAAAAAGT
TCATGTCAATCTACTTTTAATGGAAGCACGAATGCAAGCTGAACTTCTTTATGCTCTTCG
TGCCATAACTCGGCATTTGACCTGAAGTATCACCCAAGGAAAATGTCATACATGTGTAAA
GACCTTTCACATAAGATAAACATTGAAGCTATTTGTGATATAGCATCAAAAATTATTCAG
TTCTCTAGTGTCAAAGTTTAGCCGTTTGTTTTTTTTTKTTTTTTGTTTTTTGCGGCTGTA
ATGTGCAATGATGTGTTTTATTTTCCTTGATGCTTAACATTACTAACAATTGCAAAAATA
ATACTGAGGAGCACTACTTTGCATTGTTTGTAGTTGGAGTTTTGGATACTGATCATAAAT
CATGAATCTGGCGTATTAATGCTTAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_144665 unedited
CCGCGGGACCNCCNCCCCTTTCNCCCCCCGGTTCAGATTTGTATACGACTCACTTATAGG
CGGCCGCGNATTCGGCACGAGCCTAGCCTGGCGGGGGCGGGGGTCTGGAAGAGGGGGCGG
GTGGAACAACGGGCCGGTGAGGAGCAGCCGCCGCCGTCTCCGCCGTCGCTGGGGCAGCTG
CCGCGGTGGTCGCCTCTGGCAGTGCCGCTAGCTTTCAGGCAGTCGCCTCTCCTCCCGACA
TCCCGCCTTGAGGAGGCTGAGGCGGAATCGCGGCTGGCGGCGGGGGGACGGACCGGCCCT
GCAGTGGCCGCAGTGACAGCCCGGACCCGGCCCTCCGCCCGCTCTCGCCTCGGCGCCCGC
AGCCACGATGAACCGGGGCGGCGGCAGCCCGTCGGCCGCCGCCAACTACCTGCTCTGTAC
CAACTGCCGGAAAGTGCTGCGGAAGGATAAAAGAATCAGAGTGTCTCAACCCTTGACAAG
AGGACCAAGTGCCTTTATTCCAGAGAAGGAAGTTGTCCAAGCAAACACAGTGGATGAACG
TACTAACTTTCTTGTGGAAGAATACTCTACATCCGGTCGTCTGGGACACATCACACAGGT
CATGANGTTACACACTCAGTACCTGGAGTCTTTCTTGCGGAGCCAGTTTTACATGTTGCG
CATGGATGGTCCCCTTCCTCTACCATACAGGCACTATATTGCAATAATGGCTGCAGCTAG
ACATCAGTGTTCTTTACCTTATAACATGCATGTGGATGAATTTTTAAAGACTGGAGGTAT
TGCTGAATGGTGAATGGTTTGGAATTTTGCCCCAAGACTGAAAATCTTATGAATTAATAG
CTGTTACCCTTAACCTTGCTGATCCAAAGAACCTTCCTGACTTGTAAAACTGGAAAAAAA
TTGGCTTTGCTGACTGGACATGTTGGGCCCTCCTGCCCTTAAATGCTTTGAAACTT
>OriGene 3' read for NM_144665 unedited
GANGAGCCTGGGGNGGGGTCACAGGNATGCCACCCGGGTTCTGTTCAGGAAAAGCTATGA
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGCATTAA
TACGCCAGATTCATGATTTATGATCAGTATCCAAAACTCCAACTACAAACAATGCAAAGT
AGTGCTCCTCAGTATTATTTTTGCAATTGTTAGTAATGTTAAGCATCAAGGAAAATAAAA
CACATCATTGCACATTACAGCCGCAAAAAACAAAAAACAAAAAAAAACAAACGGCTAAAC
TTTGACACTAGAGAACTGAATAATTTTTGATGCTATATCACAAATAGCTTCAATGTTTAT
CTTATGTGAAAGGTCTTTACACATGTATGACATTTTCCTTGGGTGATACTTCAGGTCAAA
TGCCGAGTTATGGCACGAAGAGCATAAAGAAGTTCAGCTTGCATTCGTGCTTCCATTAAA
AGTAGATTGACATGAACTTTTTCTGAGTGTTTGAACTGCCGCCAGTAACTATCATACATG
CGTTTTGTAGTTCTCTCAGGATAGCAGGTCACTGTCTTAATGTAAACCTTCAGGCTTCTT
TCAAGTAATTGATTAACTTCTCCATAATCATAGTCATCATACCTGATTCCAAACATACAG
TGAACATAGTTAAATAAAGCTCTGCGCAGCATGGTTGTGTCAACATCCTCATGGGTGGCC
ATAGTGTTATATGTGAGATTGTAGACCATCCGAAACTTTTCATCAAGAAGATGTCCAATG
TCAGAATAAAGTCTGTTCACCAGGGGAGAACCCATGATTTTCCCAGGTTC
Restriction Sites Please inquire     
ACCN NM_144665
ORF Size 1479 bp
Insert Size 2100
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_144665.2, NP_653266.2
RefSeq Size 1987
RefSeq ORF 1479
Locus ID 143686
Domains PA26
Protein Pathways p53 signaling pathway
Gene Summary This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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