TRIM23 (NM_033228) Human Untagged Clone

CAT#: SC313946

TRIM23 (untagged)-Human tripartite motif containing 23 (TRIM23), transcript variant gamma

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM23
• Synonyms: ARD1; ARFD1; RNF46
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_033228 edited
  ATGGCTACCCTGGTTGTAAACAAGCTCGGAGCGGGAGTAGACAGTGGCCGGCAGGGCAGC
  CGGGGGACAGCTGTAGTGAAGGTGCTAGAGTGTGGAGTTTGTGAAGATGTCTTTTCTTTG
  CAAGGAGACAAAGTTCCCCGTCTTTTGCTTTGTGGCCATACCGTCTGTCATGACTGTCTC
  ACTCGCCTACCTCTTCATGGAAGAGCAATCCGTTGCCCATTTGATCGACAAGTAACAGAC
  CTAGGTGATTCAGGTGTCTGGGGATTGAAAAAAAATTTTGCTTTATTGGAGCTTTTGGAA
  CGACTGCAGAATGGGCCTATTGGTCAGTATGGAGCTGCAGAAGAATCCATTGGGATATCT
  GGAGAGAGCATCATTCGTTGTGATGAAGATGAAGCTCACCTTGCCTCTGTATATTGCACT
  GTGTGTGCAACTCATTTGTGCTCTGAGTGTTCTCAAGTTACTCATTCTACAAAGACATTA
  GCAAAGCACAGGCGAGTTCCTCTAGCTGATAAACCTCATGAGAAAACTATGTGCTCTCAG
  CACCAGGTGCATGCCATTGAGTTTGTTTGCTTGGAAGAAGGTTGTCAAACTAGCCCACTC
  ATGTGCTGTGTCTGCAAAGAATATGGAAAACACCAGGGTCACAAGCATTCAGTATTGGAA
  CCAGAAGCTAATCAGATCCGAGCATCAATTTTAGATATGGCTCACTGCATACGGACCTTC
  ACAGAGGAAATCTCAGATTATTCCAGAAAATTAGTTGGAATTGTGCAGCACATTGAAGGA
  GGAGAACAAATCGTGGAAGATGGAATTGGAATGGCTCACACAGAACATGTACCAGGGACT
  GCAGAGAATGCCCGGTCATGTATTCGAGCTTATTTTTATGATCTACATGAAACTCTGTGT
  CGTCAAGAAGAAATGGCTCTAAGTGTTGTTGATGCTCATGTTCGTGAAAAATTGATTTGG
  CTCAGGCAGCAACAAGAAGATATGACTATTTTGTTGTCAGAGGTTTCTGCAGCCTGCCTC
  CACTGTGAAAAGACTTTGCAGCAGGATGATTGTAGAGTTGTCTTGGCAAAACAGGAAATT
  ACAAGGTTACTGGAAACATTGCAGAAACAGCAGCAGCAGTTTACAGAAGTTGCAGATCAC
  ATTCAGTTGGATGCCAGCATCCCTGTCACTTTTACAAAGGATAATCGAGTTCACATTGGA
  CCAAAAATGGAAATTCGGGTCGTTACGTTAGGATTGGATGGTGCTGGAAAAACTACTATC
  TTGTTTAAGTTAAAACAGGATGAATTCATGCAGCCCATTCCAACAATTGGTTTTAACGTG
  GAAACTGTAGAATATAAAAATCTAAAATTCACTATTTGGGATGTAGGTGGAAAACACAAA
  TTAAGACCATTGTGGAAACATTATTACCTCAATACTCAAGCTGTTGTGTTTGTTGTAGAT
  AGCAGTCATAGAGACAGAATTAGTGAAGCACACAGCGAACTTGCAAAGTTGTTAACGGAA
  AAAGAACTCCGAGATGCTCTGCTCCTGATTTTTGCTAACAAACAGGATGTTGCTGGAGCA
  CTGTCAGTAGAAGAAATCACTGAACTACTCAGTCTCCATAAATTATGCTGTGGCCGTAGC
  TGTTTTTCAGATAATATGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_033228
• ORF Size: 1641 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_033228.2, NP_150231.1
• RefSeq Size: 2400
• RefSeq ORF: 1641
• Locus ID: 373
• Domains: zf-B_box, RING, RAB, BBC, SAR, ARF, arf
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (gamma) is alternatively spliced near the 3' end of the coding region. This introduces a frameshift and the encoded isoform gamma has a unique C-terminus compared to isoforms alpha and beta.