SP110 (NM_004509) Human Untagged Clone

CAT#: SC314440

SP110 (untagged)-Human SP110 nuclear body protein (SP110), transcript variant a

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP110
• Synonyms: IFI41; IFI75; IPR1; VODI
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004509 edited
  AGTGATCCCTGTCCCAGCCCCTGGAAAGGGGCAGGAACGACAAACTCAAAGTCCAGGATG
  TTCACCATGACAAGAGCCATGGAAGAGGCTCTTTTTCAGCACTTCATGCACCAGAAGCTG
  GGGATCGCCTATGCCATACACAAGCCATTTCCCTTCTTTGAAGGCCTCCTAGACAACTCC
  ATCATCACTAAGAGAATGTACATGGAATCTCTGGAAGCCTGTAGAAATTTGATCCCTGTA
  TCCAGAGTGGTGCACAACATTCTCACCCAACTGGAGAGGACTTTTAACCTGTCTCTTCTG
  GTGACATTGTTCAGTCAAATTAACCTGCGTGAATATCCCAATCTGGTGACGATTTACAGA
  AGCTTCAAACGTGTTGGTGCTTCCTATGAACGGCAGAGCAGAGACACACCAATCCTACTT
  GAAGCCCCAACTGGCCTAGCAGAAGGAAGCTCCCTCCATACCCCACTGGCGCTGCCCCCA
  CCACAACCCCCTCAACCAAGCTGTTCACCCTGTGCGCCAAGAGTCAGTGAGCCTGGAACA
  TCCTCCCAGCAAAGCGATGAGATCCTGAGTGAGTCGCCCAGCCCATCTGACCCTGTCCTG
  CCTCTCCCTGCACTCATCCAGGAAGGAAGAAGCACTTCAGTGACCAATGACAAGTTAACA
  TCCAAAATGAATGTGGAAGAAGACTCAGAAGAGATGCCCAGCCTCCTCACTAGCACTGTG
  CAAGTGGCCAGTGACAACCTGATCCCCCAAATAAGAGATAAAGAAGACCCTCAAGAGATG
  CCCCACTCTCCCTTGGGCTCTATGCCAGAGATAAGAGATAATTCTCCAGAACCAAATGAC
  CCAGAAGAGCCCCAGGAGGTGTCCAGCACACCTTCAGACAAGAAAGGAAAGAAAAGAAAA
  AGATGTATCTGGTCAACTCCAAAAAGGAGACATAAGAAAAAAAGCCTCCCAAGAGGGACA
  GCCTCATCTAGACACGGAATCCAAAAGAAGCTCAAAAGGGTGGATCAGGTTCCTCAAAAG
  AAAGATGACTCAACTTGTAACTCCACGGTAGAGACAAGGGCCCAAAAGGCGAGAACTGAA
  TGTGCCCGAAAGTCGAGATCAGAGGAGATCATTGATGGCACTTCAGAAATGAATGAAGGA
  AAGAGGTCCCAGAAGACGCCTAGTACACCACGAAGGGTCACACAAGGGGCAGCCTCACCT
  GGGCATGGCATCCAAGAGAAGCTCCAAGTGGTGGATAAGGTGACTCAAAGGAAAGACGAC
  TCAACCTGGAACTCAGAGGTCATGATGAGGGTCCAAAAGGCAAGAACTAAATGTGCCCGA
  AAGTCCAGATCGAAAGAAAAGAAAAAGGAGAAAGATATCTGTTCAAGCTCAAAAAGGAGA
  TTTCAGAAAAATATTCACCGAAGAGGAAAACCCAAAAGTGACACTGTGGATTTTCACTGT
  TCTAAGCTCCCCGTGACCTGTGGTGAGGCGAAAGGGATTTTATATAAGAAGAAAATGAAA
  CACGGATCCTCAGTGAAGTGCATTCGGAATGAGGATGGAACTTGGTTAACACCAAATGAA
  TTTGAAGTCGAAGGAAAAGGAAGGAACGCAAAGAACTGGAAACGGAATATACGTTGTGAA
  GGAATGACCCTAGGAGAGCTGCTGAAGCGGAAAAACTCGGATGAATGCGAGGTGTGCTGT
  CAAGGGGGACAACTTCTCTGCTGCGGTACTTGTCCACGAGTCTTCCATGAGGACTGTCAC
  ATCCCCCCTGTGGAAGCCAAGAGGATGCTGTGGAGTTGCACCTTCTGCAGGATGAAGAGG
  TCTTCAGGAAGCCAACAGTGCCATCATGTATCTAAGACCCTGGAGAGGCAGATGCAGCCT
  CAGGACCAGCTGATTCGAGATTACGGTGAGCCCTTTCAGGAAGCAATGTGGTTGGACCTG
  GTTAAGGAAAGGCTGATTACGGAAATGTACACGGTGGCATGGTTTGTGCGAGACATGCGC
  CTGATGTTTCGCAACCATAAAACATTTTACAAGGCTTCTGACTTTGGCCAGGTAGGACTT
  GACTTAGAGGCAGAATTTGAAAAAGATCTCAAAGACGTGCTCGGTTTTCATGAAGCCAAT
  GACGGCGGTTTCTGGACTCTTCCTTGACCCTGTTCTGTAAAGACTGAAGCATCCCCACCT
  CAGGATTCAGCTGATGGGACCCTGGCTTGGACTGTTGATTGCCAGTGAGTCTGGGATGTA
  ATTGGCTGCCCTCAGGACCCAAACCCAGACACTTCATAGGATTATCACACCCTCCATCTT
  TATTCTTTCTTTTTACCTTTAAAAGTCTATATCTACACTAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_004509
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: It is not a varient.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004509.2, NP_004500.2
• RefSeq Size: 2359 bp
• RefSeq ORF: 2070 bp
• Locus ID: 3431
• Cytogenetics: 2q37.1
• Domains: SAND, BROMO, PHD, Sp100
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (a) lacks an internal alternate exon in the 3' coding region, compared to variant c. The resulting protein (isoform a) has a truncated bromodomain region when it is compared to isoform c.