VAC14 (NM_018052) Human Untagged Clone

CAT#: SC314683

VAC14 (untagged)-Human Vac14 homolog (S. cerevisiae) (VAC14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VAC14
• Synonyms: ArPIKfyve; TAX1BP2; TRX
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018052, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACCCCGAGAAGGATTTCGCGCCGCTCACGCCTAACATCGTGCGCGCCCTCAATGACAAGCTGTACG
  AAAAGCGGAAGGTGGCAGCGCTGGAGATCGAGAAGCTGGTCCGGGAGTTCGTGGCCCAGAACAATACCGT
  GCAAATCAAGCATGTGATCCAGACCCTGTCCCAGGAGTTTGCCCTGTCTCAGCACCCCCACAGCCGGAAA
  GGGGGCCTCATCGGCCTGGCCGCCTGCTCCATCGCACTGGGCAAGGACTCAGGGCTCTACCTGAAGGAGC
  TGATCGAGCCAGTGCTGACCTGCTTCAATGATGCAGACAGCAGGCTGCGCTACTATGCCTGCGAGGCCCT
  CTACAACATCGTCAAGGTGGCCCGGGGCGCTGTGCTGCCCCACTTCAACGTGCTCTTTGACGGGCTGAGC
  AAGCTGGCAGCCGACCCAGACCCCAATGTGAAAAGCGGATCTGAGCTCCTAGACCGCCTTTTAAAGGACA
  TTGTGACTGAGAGCAACAAGTTTGACCTGGTGAGCTTCATCCCCTTGTTGCGAGAGAGGATTTACTCCAA
  CAACCAGTATGCCCGGCAGTTCATCATCTCCTGGATCCTGGTTCTGGAGTCGGTGCCAGACATTAACCTG
  CTGGATTACCTGCCGGAGATCCTGGATGGACTCTTCCAGATCCTGGGTGACAATGGCAAAGAGATTCGCA
  AAATGTGTGAGGTTGTTCTTGGAGAATTCTTAAAAGAAATTAAGAAGAACCCCTCCAGTGTGAAGTTTGC
  TGAGATGGCCAACATCCTGGTGATCCACTGCCAGACAACAGATGACCTCATCCAGCTGACAGCCATGTGC
  TGGATGCGGGAGTTCATCCAGCTGGCGGGCCGCGTCATGCTGCCTTACTCCTCCGGGATCCTGACTGCTG
  TCTTGCCCTGCTTGGCCTACGATGACCGCAAGAAAAGCATCAAAGAAGTGGCCAACGTGTGCAACCAGAG
  CCTGATGAAGCTGGTCACCCCCGAGGACGACGAGCTGGATGAGCTGAGACCTGGGCAGAGGCAGGCAGAG
  CCCACCCCTGACGATGCCCTGCCAAAGCAGGAGGGCACAGCCAGTGGAGGTCCAGATGGTTCCTGTGACT
  CCAGCTTCAGTAGCGGCATCAGTGTCTTCACTGCAGCCAGCACTGAAAGAGCCCCAGTGACCCTTCACCT
  CGACGGGATCGTGCAGGTCCTAAACTGCCACCTCAGTGACACGGCCATTGGGATGATGACCAGGATTGCA
  GTTCTCAAGTGGCTCTACCACCTCTACATCAAAACTCCTCGGAAGATGTTCCGGCACACGGACAGCCTCT
  TTCCCATCCTACTGCAGACGTTATCGGATGAATCGGATGAGGTGATCCTGAAGGACCTGGAGGTGCTGGC
  AGAAATCGCTTCCTCCCCCGCAGGCCAGACGGATGACCCAGGCCCCCTCGATGGCCCTGACCTCCAGGCC
  AGCCACTCAGAGCTCCAGGTGCCCACCCCTGGCAGAGCCGGCCTACTGAACACCTCTGGTACCAAAGGCT
  TAGAATGTTCTCCTTCAACTCCCACCATGAATTCTTACTTTTATAAGTTCATGATCAACCTTCTCAAGAG
  ATTCAGCAGCGAACGGAAGCTCCTGGAGGTCAGAGGCCCTTTCATCATCAGGCAGCTGTGCCTCCTGCTG
  AATGCGGAGAACATCTTCCACTCAATGGCAGACATCCTGCTGCGGGAGGAGGACCTCAAGTTCGCCTCGA
  CCATGGTCCACGCCCTCAACACCATCCTGCTGACCTCCACAGAGCTCTTCCAGCTAAGGAACCAGCTGAA
  GGACCTGAAGACCCTGGAGAGCCAGAACCTGTTCTGCTGCCTGTACCGCTCCTGGTGCCACAACCCAGTC
  ACCACGGTGTCCCTCTGCTTCCTCACCCAGAACTACCGGCACGCCTATGACCTCATCCAGAAGTTTGGGG
  ACCTGGAGGTCACCGTGGACTTCCTCGCAGAGGTGGACAAGCTGGTGCAGCTGATTGAGTGCCCCATCTT
  CACATATCTGCGCCTGCAGCTGCTGGACGTGAAGAACAACCCCTACCTGATCAAGGCCCTCTACGGCCTG
  CTCATGCTCCTGCCGCAGAGCAGCGCCTTCCAGCTGCTCTCGCACCGGCTCCAGTGCGTGCCCAACCCTG
  AGCTGCTGCAGACCGAAGACAGTCTAAAGGCAGCCCCCAAGTCCCAGAAAGCTGACTCCCCTAGCATCGA
  CTACGCAGAGCTGCTGCAGCACTTTGAGAAGGTCCAGAACAAGCACCTGGAAGTGCGGCACCAGCGGAGC
  GGGCGTGGGGACCACCTGGACCGGAGGGTTGTCCTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018052
• ORF Size: 2349 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018052.3, NP_060522.3
• RefSeq Size: 3107
• RefSeq ORF: 2349
• Locus ID: 55697
• Gene Summary: This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).