IL17RC (NM_153461) Human Untagged Clone

CAT#: SC314707

IL17RC (untagged)-Human interleukin 17 receptor C (IL17RC), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL17RC
• Synonyms: CANDF9; IL17-RL; IL17RL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_153461 edited
  GACTCCCAGGACAGAGAGTGCACAAACTACCCAGCACAGCCCCCTCCGCCCCCTCTGGAG
  GCTGAAGAGGGATTCCAGCCCCTGCCACCCACAGACACGGGCTGACTGGGGTGTCTGCCC
  CCCTTGGGGGGGGGCAGCACAGGGCCTCAGGCCTGGGTGCCACCTGGCACCTAGAAGATG
  CCTGTGCCCTGGTTCTTGCTGTCCTTGGCACTGGGCCGAAGCCCAGTGGTCCTTTCTCTG
  GAGAGGCTTGTGGGGCCTCAGGACGCTACCCACTGCTCTCCGGTGAGTCTGGAACCCTGG
  GGAGACGAGGAAAGGCTCAGGGTTCAGTTTTTGGCTCAGCAAAGCCTTAGCCTGGCTCCT
  GTCACTGCTGCCACTGCCAGAACTGCCCTGTCTGGTCTGTCTGGTGCTGATGGTAGAAGA
  GAAGAACGGGGAAGGGGCAAGAGCTGGGTCTGTCTTTCTCTGGGAGGGTCTGGGAATACG
  GAGCCCCAGAAAAAGGGCCTCTCCTGCCGCCTCTGGGACAGTGACATACTCTGCCTGCCT
  GGGGACATCGTGCCTGCTCCGGGCCCCGTGCTGGCGCCTACGCACCTGCAGACAGAGCTG
  GTGCTGAGGTGCCAGAAGGAGACCGACTGTGACCTCTGTCTGCGTGTGGCTGTCCACTTG
  GCCGTGCATGGGCACTGGGAAGAGCCTGAAGATGAGGAAAAGTTTGGAGGAGCAGCTGAC
  TCAGGGGTGGAGGAGCCTAGGAATGCCTCTCTCCAGGCCCAAGTCGTGCTCTCCTTCCAG
  GCCTACCCTACTGCCCGCTGCGTCCTGCTGGAGGTGCAAGTGCCTGCTGCCCTTGTGCAG
  TTTGGTCAGTCTGTGGGCTCTGTGGTATATGACTGCTTCGAGGCTGCCCTAGGGAGTGAG
  GTACGAATCTGGTCCTATACTCAGCCCAGGTACGAGAAGGAACTCAACCACACACAGCAG
  CTGCCTGACTGCAGGGGGCTCGAAGTCTGGAACAGCATCCCGAGCTGCTGGGCCCTGCCC
  TGGCTCAACGTGTCAGCAGATGGTGACAACGTGCATCTGGTTCTGAATGTCTCTGAGGAG
  CAGCACTTCGGCCTCTCCCTGTACTGGAATCAGGTCCAGGGCCCCCCAAAACCCCGGTGG
  CACAAAAACCTGACTGGACCGCAGATCATTACCTTGAACCACACAGACCTGGTTCCCTGC
  CTCTGTATTCAGGTGTGGCCTCTGGAACCTGACTCCGTTAGGACGAACATCTGCCCCTTC
  AGGGAGGACCCCCGCGCACACCAGAACCTCTGGCAAGCCGCCCGACTGCGACTGCTGACC
  CTGCAGAGCTGGCTGCTGGACGCACCGTGCTCGCTGCCCGCAGAAGCGGCACTGTGCTGG
  CGGGCTCCGGGTGGGGACCCCTGCCAGCCACTGGTCCCACCGCTTTCCTGGGAGAACGTC
  ACTGTGGACAAGGTTCTCGAGTTCCCATTGCTGAAAGGCCACCCTAACCTCTGTGTTCAG
  GTGAACAGCTCGGAGAAGCTGCAGCTGCAGGAGTGCTTGTGGGCTGACTCCCTGGGGCCT
  CTCAAAGACGATGTGCTACTGTTGGAGACACGAGGCCCCCAGGACAACAGATCCCTCTGT
  GCCTTGGAACCCAGTGGCTGTACTTCACTACCCAGCAAAGCCTCCACGAGGGCAGCTCGC
  CTTGGAGAGTACTTACTACAAGACCTGCAGTCAGGCCAGTGTCTGCAGCTATGGGACGAT
  GACTTGGGAGCGCTATGGGCCTGCCCCATGGACAAATACATCCACAAGCGCTGGGCCCTC
  GTGTGGCTGGCCTGCCTACTCTTTGCCGCTGCGCTTTCCCTCATCCTCCTTCTCAAAAAG
  GATCACGCGAAAGGGTGGCTGAGGCTCTTGAAACAGGACGTCCGCTCGGGGGCGGCCGCC
  AGGGGCCGCGCGGCTCTGCTCCTCTACTCAGCCGATGACTCGGGTTTCGAGCGCCTGGTG
  GGCGCCCTGGCGTCGGCCCTGTGCCAGCTGCCGCTGCGCGTGGCCGTAGACCTGTGGAGC
  CGTCGTGAACTGAGCGCGCAGGGGCCCGTGGCTTGGTTTCACGCGCAGCGGCGCCAGACC
  CTGCAGGAGGGCGGCGTGGTGGTCTTGCTCTTCTCTCCCGGTGCGGTGGCGCTGTGCAGC
  GAGTGGCTACAGGATGGGGTGTCCGGGCCCGGGGCGCACGGCCCGCACGACGCCTTCCGC
  GCCTCGCTCAGCTGCGTGCTGCCCGACTTCTTGCAGGGCCGGGCGCCCGGCAGCTACGTG
  GGGGCCTGCTTCGACAGGCTGCTCCACCCGGACGCCGTACCCGCCCTTTTCCGCACCGTG
  CCCGTCTTCACACTGCCCTCCCAACTGCCAGACTTCCTGGGGGCCCTGCAGCAGCCTCGC
  GCCCCGCGTTCCGGGCGGCTCCAAGAGAGAGCGGAGCAAGTGTCCCGGGCCCTTCAGCCA
  GCCCTGGATAGCTACTTCCATCCCCCGGGGACTCCCGCGCCGGGACGCGGGGTGGGACCA
  GGGGCGGGACCTGGGGCGGGGGACGGGACTTAAATAAAGGCAGACGCT
  
• Restriction Sites: Please inquire
• ACCN: NM_153461
• ORF Size: 2376 bp
• Insert Size: 2600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: It is not a varient.

Reference Data

• RefSeq: NM_153461.1, NP_703191.1
• RefSeq Size: 2691
• RefSeq ORF: 2376
• Locus ID: 84818
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
  Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal coding exon compared to variant 1, resulting in a longer isoform (2) containing an additional protein segment compared to isoform 1.