PCDHA9 (NM_014005) Human Untagged Clone

CAT#: SC314803

PCDHA9 (untagged)-Human protocadherin alpha 9 (PCDHA9), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA9
• Synonyms: PCDH-ALPHA9
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014005, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTATACTCAAGTCGAGGAGATCCAGAGGGTCAGCCTCTACTGCTCTCGCTTCTGATCCTCGCAATGT
  GGGTGGTGGGGAGCGGCCAGCTCCACTACTCCGTCCCGGAGGAAGCCGAACACGGCACCTTCGTGGGCCG
  CATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCCGCGCCTGTTCCAGTTGGATTCCAAAGGC
  CGCGGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGG
  AGCTGTGCGGGCGGAGCGCGGAGTGCAGCATCCACCTGGAGGTGATCGTAGACAGGCCGCTGCAGGTTTT
  CCATGTGGACGTGGAGGTGAAGGACATTAACGACAACCCTCCAGTGTTCCCAGCGACACAAAAGAATCTG
  TTCATCGCGGAATCCAGGCCGCTTGACTCTCGGTTTCCACTAGAGGGCGCGTCCGATGCAGATATCGGGG
  AGAACGCCCTGCTCACTTACAGACTGAGCCCCAATGAGTATTTCTTCCTGGACGTGCCAACCAGCAACCA
  GCAGGTAAAACCTCTTGGACTTGTATTACGGAAACTTTTAGACAGAGAAGAAACTCCGGAGCTTCATTTA
  TTGCTCACGGCCACCGATGGAGGCAAACCCGAGCTGACTGGCACCGTTCAATTACTCATCACGGTACTGG
  ACAACAATGACAATGCCCCAGTGTTCGACAGAACCCTGTATACGGTGAAATTACCAGAAAACGTTTCTAT
  CGGAACGCTGGTGATTCACCCCAATGCCTCAGATTTAGACGAAGGCTTGAATGGGGATATTATTTACTCC
  TTCTCCAGTGATGTTTCTCCAGATATAAAATCCAAGTTCCACATGGACCCCTTAAGTGGGGCAATCACAG
  TGATAGGACATATGGATTTTGAAGAAAGTAGAGCACACAAGATCCCAGTCGAGGCTGTCGATAAAGGCTT
  CCCACCCCTGGCTGGTCATTGTACACTTCTTGTGGAAGTTGTGGATGTAAATGACAATGCTCCACAGTTG
  ACTATCAAAACGCTCTCGGTTCCTGTAAAAGAGGACGCACAACTGGGGACAGTTATTGCCCTGATTAGTG
  TGATCGACCTAGACGCAGATGCCAACGGGCAGGTTACCTGCTCCCTGACGCCCCACGTCCCCTTCAAGCT
  GGTGTCCACCTACAAGAATTACTACTCGTTGGTGCTGGACAGAGCTCTGGACCGCGAGAGTGTGTCCGCC
  TACGAGCTGGTGGTTACCGCGCGGGACGGGGGCTCGCCTTCACTGTGGGCCACGGCCAGGGTGTCTGTGG
  AGGTGGCCGACGTGAACGACAACGCACCAGCGTTCGCGCAGTCCGAGTACACGGTGTTCGTGAAGGAGAA
  CAACCCGCCGGGCTGCCACATCTTCACGGTGTCTGCGCGGGACGCTGACGCGCAGGAGAACGCCCTGGTG
  TCCTACTCGCTGGTGGAGCGGCGGTTGGGCGAGCGCTCGCTGTCGAGCTACGTGTCAGTGCACGCGGAGA
  GCGGCAAGGTGTACGCGCTGCAGCCGTTGGACCACGAGGAGCTGGAGCTGCTACAGTTCCAGGTGAGCGC
  GCGCGACGCGGGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AATGCGCCGGCGCTGCTGACACCTCGGATGAGGGGCACTGACGGCGCAGTGAGCGAGATGGTGCTGCGGT
  CGGTGGGCGCCGGCGTAGTGGTGGGGAAGGTGCGCGCAGTGGACGCCGACTCGGGCTACAACGCGTGGCT
  TTCATACGAGCTGCAGCCAGAAACGGCCAGCGCGAGCATCCCGTTCCGCGTGGGGCTGTACACGGGCGAG
  ATCAGCACAACGCGTGCCCTGGACGAAACGGACGCACCGCGCCAGCGCCTACTGGTGCTGGTGAAAGACC
  ACGGGGAGCCAGCGCTGACGGCCACGGCCACTGTGCTGGTGTCGCTGGTGGAGAGCGGCCAGGCGCCAAA
  GTCATCGTCGCGGGCGTCAGTGGGTGCCACGGGCCCCGAGGTGACGCTGGTGGATGTCAACGTGTACCTG
  ATCATCGCCATCTGCGCGGTGTCTAGCCTGTTGGTTCTCACGCTGCTGCTGTACACTGTGCTGCGGTGCT
  CGGCGATGCCCACCGAGGGCGAGTGCGCGCCTGGCAAGCCGACGCTGGTGTGTTCTAGCGCGGTGGGGAG
  TTGGTCGTACTCGCAGCAGAGGAGGCAGAGGGTGTGCTCTGGCGAGGGTAAGCAGAAGACCGACCTCATG
  GCCTTCAGCCCGGGCCTTTCTCCTTGTGCTGGATCTACAGAGCGAACGGGAGAACCCTCTGCTTCCTCAG
  ATTCAACTGGGAAGGTGGGTTTTTCTAGCATTTTATTTATTTATATAATTTTTTTTCTTGAAAGATATTA
  TCGATTACTCCCAGGGGCCGTTCAAATAGTTTTATTCATTTTTCTAGAAATCCAGCAGATTTTTTTTCTG
  ATAAAGTAA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_014005
• ORF Size: 2529 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014005.4, NP_054724.1
• RefSeq Size: 6388
• RefSeq ORF: 2529
• Locus ID: 9752
• Domains: CA
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.