RNF20 (NM_019592) Human Untagged Clone

CAT#: SC315020

RNF20 (untagged)-Human ring finger protein 20 (RNF20)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF20
• Synonyms: BRE1; BRE1A; hBRE1
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_019592 edited
  TTCTGCCTTGTCTCCGCCGCGGGTCAGGGGTGAGAGCTGGAATCTCTGCACGGGCCTTGG
  AAAACGACTGTCTTCTTCTGCCAAAATGTCAGGAATTGGAAATAAAAGAGCAGCTGGAGA
  ACCTGGCACCTCCATGCCTCCTGAGAAGAAGGCAGCTGTTGAAGATTCAGGGACCACAGT
  GGAAACAATTAAGCTAGGAGGTGTCTCTTCAACGGAGGAACTAGACATTAGAACACTGCA
  AACCAAAAATCGCAAGCTGGCAGAAATGTTGGATCAGCGGCAGGCCATTGAAGATGAACT
  TCGTGAGCACATTGAAAAACTGGAACGACGACAGGCCACTGATGATGCCTCACTATTGAT
  TGTCAACCGATACTGGAGTCAGTTTGATGAAAACATCCGTATCATCCTTAAACGTTATGA
  TCTGGAGCAGGGCTTGGGAGACCTACTCACAGAACGAAAAGCCCTTGTTGTGCCTGAACC
  AGAACCAGACTCTGATAGCAATCAGGAGCGTAAAGATGACCGAGAGAGAGGGGAAGGGCA
  AGAGCCAGCTTTCTCTTTCCTTGCTACTTTGGCCAGCAGTTCCAGTGAAGAGATGGAGTC
  TCAGCTGCAGGAACGTGTGGAGTCTTCCCGCCGAGCCGTGTCCCAGATTGTGACTGTTTA
  TGATAAATTGCAAGAAAAAGTGGAGCTCTTATCCCGGAAGCTAAACAGTGGAGATAATCT
  GATAGTGGAGGAAGCAGTGCAGGAGCTGAACTCTTTCCTCGCACAGGAGAATATGAGGCT
  ACAGGAATTGACAGATCTTCTTCAGGAAAAGCATCGCACCATGTCTCAGGAGTTCTCCAA
  GTTGCAGAGTAAAGTGGAGACAGCCGAATCACGAGTGTCTGTCCTGGAGTCCATGATTGA
  TGACCTGCAGTGGGATATTGACAAAATTCGAAAGAGGGAACAGCGACTCAACCGACACTT
  AGCAGAAGTCCTAGAACGGGTGAATTCCAAAGGTTATAAGGTGTATGGAGCGGGGAGCAG
  TCTGTATGGCGGCACAATCACTATCAATGCTCGGAAGTTTGAGGAAATGAATGCAGAGCT
  TGAGGAGAACAAAGAGTTGGCTCAGAACCGTCTCTGTGAGCTGGAGAAACTTCGGCAAGA
  CTTTGAGGAGGTCACTACACAAAATGAAAAGCTGAAGGTGGAATTGCGGAGTGCAGTGGA
  GCAAGTCGTTAAGGAAACTCCAGAATATCGCTGCATGCAGTCACAGTTCTCCGTCTTGTA
  TAATGAGAGCCTACAGTTGAAAGCACACTTGGATGAGGCTCGGACCCTGCTTCATGGCAC
  CAGAGGAACCCACCAGCACCAGGTTGAGCTTATTGAGCGAGATGAGGTTAGTCTTCATAA
  GAAGCTGAGGACTGAAGTAATTCAGCTAGAAGATACATTGGCCCAGGTCCGCAAGGAGTA
  TGAAATGCTGAGGATAGAATTTGAGCAGACCCTTGCTGCCAATGAACAAGCAGGCCCTAT
  AAACAGGGAGATGCGCCACCTCATCAGTAGCCTCCAGAATCACAATCACCAGCTGAAAGG
  GGAGGTCCTGAGATATAAGCGGAAATTGAGAGAAGCCCAGTCTGACCTGAACAAGACACG
  CCTGCGTAGTGGTAGTGCCCTCCTGCAGTCCCAGTCTAGTACTGAGGACCCGAAGGATGA
  GCCTGCGGAGCTAAAACCAGATTCTGAGGACTTATCCTCCCAGTCCTCAGCTTCAAAGGC
  ATCTCAGGAGGATGCCAATGAAATCAAGTCTAAACGGGATGAAGAAGAACGAGAACGAGA
  AAGGAGGGAGAAGGAGAGGGAACGAGAAAGAGAACGGGAGAAGGAGAAGGAGAGAGAACG
  AGAGAAGCAGAAGCTAAAAGAGTCAGAAAAAGAGAGAGATTCTGCTAAGGATAAAGAGAA
  AGGCAAACATGATGATGGACGGAAAAAGGAAGCAGAAATTATCAAACAATTGAAGATTGA
  ACTCAAGAAGGCACAGGAGAGCCAAAAGGAGATGAAACTATTGCTGGATATGTACCGTTC
  TGCCCCAAAGGAACAGAGAGACAAAGTTCAGCTGATGGCAGCTGAGAAGAAGTCTAAGGC
  AGAGTTGGAAGATCTAAGGCAAAGACTCAAGGATCTGGAAGATAAAGAGAAGAAAGAGAA
  CAAGAAAATGGCTGATGAGGATGCCTTGAGGAAGATCCGGGCAGTGGAGGAGCAGATAGA
  ATACCTACAGAAGAAGCTAGCCATGGCCAAGCAGGAAGAAGAAGCACTCCTCTCTGAAAT
  GGATGTCACAGGCCAGGCCTTTGAAGACATGCAGGAGCAAAATATCCGTTTGATGCAGCA
  ATTGCGGGAGAAGGATGATGCAAATTTCAAGCTCATGTCAGAGCGTATCAAGTCCAATCA
  GATCCATAAGTTGCTTAAAGAAGAGAAGGAGGAGCTGGCAGACCAGGTGTTGACTCTGAA
  GACTCAGGTTGATGCCCAGCTACAGGTAGTAAGGAAACTGGAAGAGAAGGAGCATCTGTT
  ACAGAGCAACATTGGCACAGGGGAGAAAGAGCTGGGTCTTAGGACCCAAGCCTTAGAGAT
  GAATAAACGCAAGGCAATGGAGGCAGCCCAGCTTGCAGATGACCTCAAAGCACAACTGGA
  GTTGGCTCAGAAGAAGCTACATGATTTTCAGGATGAGATCGTGGAGAACAGTGTTACCAA
  AGAAAAGGACATGTTCAATTTCAAACGAGCCCAGGAGGACATCTCTAGACTTCGCAGGAA
  GCTGGAGACCACAAAGAAACCAGACAATGTACCCAAGTGTGATGAGATTCTGATGGAAGA
  GATTAAGGATTACAAGGCACGCTTGACCTGTCCGTGCTGTAACATGCGTAAAAAGGATGC
  TGTTCTTACTAAGTGTTTTCATGTCTTCTGCTTTGAGTGTGTGAAGACACGCTATGACAC
  CCGCCAGCGCAAATGTCCCAAGTGTAATGCTGCTTTTGGTGCCAATGATTTTCATCGCAT
  CTACATTGGTTGATCTAAGTCAAGAGAAGAAGAGGAGCTGGCTAGTCAGGAACTTATTCA
  TTAACCACCAAACCTCTACCTCTTCTCTCCTTGACTGTCACCTGTAGGACAGTTTATCAG
  TCAACTACCTTTCCTCCAGACTTTACTTCCAGGCTCTCCTCTTCAGTAGCTGGATGACTT
  TAGCAGAAAGGACTGGTAAATACAAGCCTTGGGTTTCAGAATGAATTAGAAACAAATAAC
  TCTTACTGTCTTCCCTCCCAGCTTTGTTTATTTTGTGCTTTTAGACTTTTCAGTGTTTTC
  TTTTTCCAGCCCACTGTATAAACTTGGATTGTCCATTCCTCCTGAAGAAATCAAGTTGGT
  ATTTTTGATGTGGAAAAGGGAACAAAAGTGGAAACATGGCTACTTTTGGGGAGTGATATT
  TTAAAAAATAAGTTGTCTATGGGCACAAAGTTTTCTTCATTTGTGTAGCAAACTTCTTGT
  GAATGTGGATTACAAAATGGTATAATTGTGCTACTCTCCCCTGGGTGGTTTGCAGCCCTA
  ATGAAATTATGTCTAGGATGATTCAGTCTATTTCCCATTTACTAGCAGAGTAACTTGTTA
  AGATCAGCTGGCTTTCTTGTTAAAGTTATTTAAGTTTTGAATGCTCTACTACTTCAAGTC
  TTTAAATTTCTTGAGACTAGAATAATTTTAAATAATATGACCCTTTGTCTTCTAATGAAA
  TAAAGATTGAAGAGGTTGAGTATAGTCC
  
• Restriction Sites: Please inquire
• ACCN: NM_019592
• ORF Size: 2928 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_019592.5.

Reference Data

• RefSeq: NM_019592.5, NP_062538.5
• RefSeq Size: 3970
• RefSeq ORF: 2928
• Locus ID: 56254
• Domains: RING
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]