FBH1 (NM_032807) Human Untagged Clone

CAT#: SC315174

FBXO18 (untagged)-Human F-box protein, helicase, 18 (FBXO18), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBH1
• Synonyms: Fbx18; FBXO18; hFBH1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032807, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCTACGAGGTGACTTCAGGCTGCCATTGGACCTGTCAAGTGCCTGAGTCATGTGATAATGGGCTAC
  ATTGCGCAGGGCCCCTGGGCCATCTCCACAGGAGATGCCAGAGGACGAGTGCCCACTTGCTGGTCTTCAC
  AGAGCACGCTGAAATGAGACGGTTTAAGCGGAAGCATCTTACTGCCATTGACTGCCAGCATTTGGCTCGG
  AGTCACTTGGCTGTGACCCAGCCCTTCGGTCAAAGATGGACAAACAGAGATCCGAACCATGGTCTCTATC
  CTAAACCGAGAACAAAAAGAGGGAGTAGGGGTCAGGGAAGTCAAAGATGCATCCCTGAGTTCTTCCTAGC
  AGGCAAGCAGCCGTGCACCAATGACATGGCCAAAAGCAATTCTGTTGGCCAGGACAGCTGTCAGGACTCT
  GAGGGTGACATGATCTTTCCTGCAGAGAGCAGCTGTGCACTGCCTCAGGAAGGCAGTGCAGGGCCGGGCT
  CACCAGGGTCTGCCCCGCCCTCCAGGAAGCGGTCTTGGTCCTCTGAGGAAGAGAGTAACCAGGCTACCGG
  GACCAGCCGGTGGGATGGAGTTTCTAAGAAAGCTCCACGGCACCATTTGTCTGTGCCATGCACAAGGCCT
  AGGGAGGCCAGGCAAGAAGCAGAGGACAGTACGTCTCGGCTCTCTGCGGAGTCTGGTGAAACCGACCAAG
  ATGCTGGGGACGTGGGTCCTGATCCCATTCCTGACTCATACTATGGGCTTCTTGGGACCTTGCCCTGCCA
  GGAAGCACTGAGCCACATTTGCAGCCTGCCTAGTGAGGTCCTGAGGCACGTGTTTGCCTTCCTCCCGGTG
  GAAGACCTCTATTGGAACCTGAGCTTGGTGTGCCACTTGTGGAGGGAGATCATCAGTGACCCGCTGTTCA
  TTCCTTGGAAGAAGCTGTACCATCGATACCTGATGAATGAAGAGCAAGCTGTCAGCAAAGTGGACGGCAT
  CCTGTCTAACTGTGGCATAGAAAAGGAGTCAGACCTGTGTGTGCTGAACCTCATACGATACACAGCCACC
  ACTAAGTGCTCTCCGAGTGTGGATCCCGAGAGGGTGCTGTGGAGTCTGAGGGACCACCCCCTCCTCCCCG
  AGGCTGAGGCGTGTGTGCGGCAACACCTCCCCGACCTCTACGCTGCTGCCGGGGGTGTCAACATCTGGGC
  CCTGGTGGCGGCTGTGGTGCTCCTCTCCAGCAGTGTGAATGACATCCAGCGACTGCTCTTCTGCCTCCGG
  AGACCCAGCTCCACGGTGACCATGCCAGATGTCACCGAGACCCTGTACTGCATAGCCGTGCTTCTCTACG
  CCATGAGGGAGAAGGGGATTAACATCAGCAATAGGATTCACTACAACATTTTCTATTGCCTATATCTTCA
  GGAGAATTCCTGCACTCAGGCCACAAAAGTTAAAGAGGAGCCATCTGTCTGGCCAGGCAAGAAAACCATC
  CAACTTACACATGAACAACAGCTGATTCTGAATCACAAGATGGAACCTCTCCAGGTGGTGAAAATTATGG
  CCTTTGCCGGCACTGGGAAGACCTCAACGCTGGTCAAGTATGCAGAGAAGTGGTCTCAGAGCAGGTTTCT
  GTATGTGACATTCAACAAGAGCATCGCAAAGCAGGCCGAACGCGTCTTCCCCAGCAACGTCATCTGCAAA
  ACCTTCCACTCCATGGCCTACGGGCACATAGGGCGGAAGTACCAGTCAAAGAAGAAGTTGAATCTCTTCA
  AGTTAACACCCTTCATGGTCAACTCCGTCCTTGCTGAAGGGAAGGGTGGATTCATAAGAGCCAAGCTTGT
  GTGTAAGACTCTAGAAAACTTCTTTGCCTCGGCTGACGAAGAGCTGACCATTGATCACGTGCCTATTTGG
  TGTAAGAACAGCCAAGGACAGAGAGTCATGGTTGAGCAGAGTGAAAAACTGAATGGTGTCCTTGAAGCGA
  GCCGCCTCTGGGATAACATGCGGAAGCTGGGGGAGTGCACAGAAGAGGCGCACCAGATGACTCATGACGG
  CTACTTGAAACTCTGGCAGCTGAGCAAGCCTTCGCTGGCCTCTTTTGACGCCATCTTTGTGGATGAGGCC
  CAGGACTGCACACCAGCTATCATGAACATAGTTCTGTCTCAGCCATGTGGGAAAATCTTTGTAGGGGACC
  CGCACCAGCAGATCTATACCTTCCGGGGTGCGGTCAACGCCCTGTTCACAGTGCCCCACACCCACGTCTT
  CTATCTCACGCAGAGTTTTCGGTTTGGTGTGGAAATAGCTTATGTGGGAGCTACTATCTTGGATGTTTGC
  AAGAGAGTCAGGAAAAAGACTTTGGTTGGAGGAAACCATCAGAGTGGCATTAGAGGTGACGCAAAGGGGC
  AAGTGGCCTTGTTGTCCCGGACCAACGCCAACGTGTTTGATGAGGCCGTACGGGTGACGGAAGGGGAATT
  CCCTTCAAGGATACATTTGATTGGGGGGATTAAATCATTTGGATTGGACAGAATCATTGATATTTGGATC
  CTTCTTCAGCCAGAGGAAGAACGGAGGAAACAAAACCTCGTCATTAAAGACAAATTTATCAGAAGATGGG
  TGCACAAAGAAGGCTTTAGTGGCTTCAAGAGGTATGTGACCGCTGCCGAGGACAAGGAGCTTGAAGCCAA
  GATCGCAGTTGTTGAAAAGTATAACATCAGGATTCCAGAGCTGGTGCAAAGGATAGAAAAATGCCATATA
  GAAGATTTGGACTTTGCAGAGTACATTCTGGGCACTGTGCACAAAGCCAAAGGCCTGGAGTTTGACACTG
  TGCATGTTTTGGATGATTTTGTGAAAGTGCCTTGTGCCCGGCATAACCTGCCCCAGCTTCCGCACTTCAG
  AGTTGAGTCATTTTCTGAGGATGAATGGAATTTACTGTATGTTGCAGTAACTCGAGCCAAGAAGCGTCTC
  ATCATGACCAAATCATTGGAAAACATTTTGACTTTGGCTGGGGAGTACTTCTTGCAAGCAGAGCTGACAA
  GCAACGTCTTAAAAACAGGCGTGGTGCGCTGCTGCGTGGGACAGTGCAACAATGCCATCCCTGTTGACAC
  CGTCCTTACCATGAAGAAGCTGCCCATCACCTATAGCAACAGGAAGGAAAACAAGGGGGGCTACCTCTGC
  CACTCCTGTGCGGAGCAGCGCATCGGGCCCCTGGCGTTCCTGACAGCCTCCCCGGAGCAGGTGCGCGCCA
  TGGAGCGCACTGTGGAGAACATCGTACTGCCCCGGCATGAGGCCCTGCTCTTCCTCGTCTTCTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_032807
• ORF Size: 3285 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032807.4, NP_116196.3
• RefSeq Size: 3718
• RefSeq ORF: 3285
• Locus ID: 84893
• Domains: F-box
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).