SCAP (NM_012235) Human Untagged Clone

CAT#: SC315330

SCAP (untagged)-Human SREBF chaperone (SCAP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCAP
• Synonyms: KIAA0199
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012235 edited
  AGGGTGATCCATGGTCACTTTCCGGGATGGCAGCAAGGTGACTTCGGCTGAGGATGACCC
  TGACTGAAAGGCTGCGTGAGAAGATATCTCGGGCCTTCTACAACCATGGGCTCCTCTGTG
  CATCCTATCCCATCCCCATCATCCTCTTCACAGGGTTCTGCATCTTAGCCTGCTGCTACC
  CACTGCTGAAACTCCCCTTGCCAGGAACAGGACCTGTGGAATTCACCACCCCTGTGAAGG
  ATTACTCGCCCCCACCTGTGGACTCTGACCGCAAACAAGGAGAGCCTACTGAGCAGCCTG
  AGTGGTATGTGGGTGCCCCGGTGGCTTATGTCCAGCAGATATTTGTGAAGTCCTCAGTGT
  TTCCCTGGCACAAGAACCTCCTGGCAGTAGATGTATTTCGTTCACCTTTGTCCCGGGCAT
  TCCAACTGGTGGAGGAGATCCGGAACCACGTGCTGAGAGACAGCTCTGGGATCAGGAGCT
  TGGAGGAGTTGTGTCTGCAAGTGACCGACCTGCTGCCAGGCCTTAGGAAGCTCAGGAACC
  TACTCCCTGAGCATGGATGCCTGCTGCTGTCCCCTGGGAACTTCTGGCAGAATGACTGGG
  AACGCTTCCATGCTGATCCTGACATCATTGGGACCATCCACCAGCACGAGCCTAAAACCC
  TGCAGACTTCAGCCACACTCAAAGACTTGTTATTTGGTGTTCCTGGGAAGTACAGCGGGG
  TGAGCCTCTACACCAGGAAGAGGATGGTCTCCTACACCATCACCCTGGTCTTCCAGCACT
  ACCATGCCAAGTTCCTGGGCAGCCTGCGTGCCCGCCTGATGCTTCTGCACCCCAGCCCCA
  ACTGCAGCCTTCGGGCGGAGAGCCTGGTCCACGTGCACTTCAAGGAGGAGATTGGTGTCG
  CTGAGCTCATCCCCCTTGTGACCACCTACATCATCTTGTTTGCCTACATCTACTTCTCCA
  CGCGGAAGATCGACATGGTCAAGTCCAAGTGGGGGCTGGCCCTGGCTGCCGTGGTCACAG
  TGCTCAGCTCGCTGCTCATGTCTGTGGGACTCTGCACACTCTTCGGCCTGACGCCCACCC
  TCAATGGCGGCGAGATTTTCCCCTACCTTGTGGTGGTTATTGGGTTAGAGAATGTGTTGG
  TGCTCACCAAGTCTGTGGTCTCAACCCCGGTAGACCTGGAGGTGAAGCTGCGGATCGCCC
  AAGGCCTAAGCAGCGAGAGCTGGTCCATCATGAAGAACATGGCCACGGAGCTGGGCATCA
  TCCTCATCGGCTACTTCACCCTAGTGCCCGCCATCCAGGAGTTCTGTCTCTTTGCTGTCG
  TGGGGCTGGTGTCTGACTTCTTCCTTCAGATGCTGTTTTTCACCACTGTCCTGTCCATTG
  ACATTCGCCGGATGGAGCTAGCAGACCTGAACAAGCGACTGCCCCCTGAGGCCTGCCTGC
  CCTCAGCCAAGCCAGTGGGGCAGCCAACGCGCTACGAGCGGCAGCTGGCTGTGAGGCCGT
  CCACACCCCACACCATCACGTTGCAGCCGTCTTCCTTCCGAAACCTGCGGCTCCCCAAGA
  GGCTGCGTGTTGTCTACTTCCTGGCCCGCACCCGCCTGGCACAGCGCCTCATCATGGCTG
  GCACCGTTGTCTGGATTGGCATCCTGGTATACACAGACCCAGCAGGGCTGCGCAACTACC
  TCGCTGCCCAGGTGACGGAACAGAGCCCATTGGGTGAGGGAGCCCTGGCTCCCATGCCCG
  TGCCTAGTGGCATGCTGCCCCCCAGCCACCCGGACCCTGCCTTCTCCATCTTCCCACCTG
  ATGCCCCTAAGCTACCTGAGAACCAGACGTCGCCAGGCGAGTCACCTGAGCGTGGAGGTC
  CAGCAGAGGTTGTCCATGACAGCCCAGTCCCAGAGGTAACCTGGGGGCCTGAGGATGAGG
  AACTTTGGAGGAAATTGTCCTTCCGCCACTGGCCGACGCTCTTCAGCTATTACAACATCA
  CACTGGCCAAGAGGTACATCAGCCTGCTGCCCGTCATCCCAGTCACGCTCCGCCTGAACC
  CGAGGGAGGCTCTGGAGGGCCGGCACCCTCAGGACGGCCGCAGTGCCTGGCCCCCACCGG
  GGCCCATACCTGCTGGGCACTGGGAAGCAGGACCCAAGGGCCCAGGTGGGGTGCAGGCCC
  ATGGAGACGTCACGCTGTACAAGGTGGCGGCGCTGGGCCTGGCCACCGGCATCGTCTTGG
  TGCTGCTGCTGCTCTGCCTCTACCGCGTGCTATGCCCGCGCAACTACGGGCAGCTGGGTG
  GTGGGCCCGGGCGGCGGAGGCGCGGGGAGCTGCCCTGCGACGACTACGGCTATGCGCCAC
  CCGAGACGGAGATCGTGCCGCTTGTGCTGCGCGGCCACCTCATGGACATCGAGTGCCTGG
  CCAGCGACGGCATGCTGCTGGTGAGCTGCTGCCTGGCAGGCCACATCTGCGTGTGGGACG
  CGCAGACCGGGGATTGCCTAACGCGCATTCCGCGCCCAGGCAGGCAGCGCCGGGACAGTG
  GCGTGGGCAGCGGGCTTGAGGCTCAGGAGAGCTGGGAACGACTTTCAGATGGTGGGAAGG
  CTGGTCCAGAGGAGCCTGGGGACAGCCCTCCCCTGAGACACCGCCCCCGGGGCCCTCCGC
  CGCCTTCCCTCTTCGGGGACCAGCCTGACCTCACCTGCTTAATTGACACCAACTTTTCAG
  CGCAGCCTCGGTCCTCACAGCCCACTCAGCCCGAGCCCCGGCACCGGGCGGTCTGTGGCC
  GCTCTCGGGACTCCCCAGGCTATGACTTCAGCTGCCTGGTGCAGCGGGTGTACCAGGAGG
  AGGGGCTGGCGGCCGTCTGCACACCAGCCCTGCGCCCACCCTCGCCTGGGCCGGTGCTGT
  CCCAGGCCCCTGAGGACGAGGGTGGCTCCCCCGAGAAAGGCTCCCCTTCCCTCGCCTGGG
  CCCCCAGTGCCGAGGGTTCCATCTGGAGCTTGGAGCTGCAGGGCAACCTCATCGTGGTGG
  GGCGGAGCAGCGGCCGGCTGGAGGTGTGGGACGCCATTGAAGGGGTGCTGTGCTGCAGCA
  GCGAGGAGGTCTCCTCAGGCATTACCGCTCTGGTGTTCTTGGACAAAAGGATTGTGGCTG
  CACGGCTCAACGGTTCCCTTGATTTCTTCTCCTTGGAGACCCACACTGCCCTCAGCCCCC
  TGCAGTTTAGAGGGACCCCAGGGCGGGGCAGTTCCCCTGCCTCTCCAGTGTACAGCAGCA
  GCGACACAGTGGCCTGTCACCTGACCCACACAGTGCCCTGTGCACACCAAAAACCCATCA
  CAGCCCTGAAAGCCGCTGCTGGGCGCTTGGTGACTGGGAGCCAAGACCACACACTGAGAG
  TGTTCCGTCTGGAGGACTCGTGCTGCCTCTTCACCCTTCAGGGCCACTCAGGGGCCATCA
  CGACCGTGTACATTGACCAGACCATGGTGCTGGCCAGTGGAGGACAAGATGGGGCCATCT
  GCCTGTGGGATGTACTGACTGGCAGCCGGGTCAGCCATGTGTTTGCTCACCGTGGGGATG
  TCACCTCCCTTACCTGTACCACCTCCTGTGTCATCAGCAGTGGCCTGGATGACCTCATCA
  GCATCTGGGACCGCAGCACAGGCATCAAGTTCTACTCCATTCAGCAGGACCTGGGCTGTG
  GTGCAAGCTTGGGTGTCATCTCAGACAACCTGCTGGTGACTGGCGGCCAGGGCTGTGTCT
  CCTTTTGGGACCTAAACTACGGGGACCTGTTACAGACAGTCTACCTGGGGAAGAACAGTG
  AGGCCCAGCCTGCCCGCCAGATCCTGGTGCTGGACAACGCTGCCATTGTCTGCAACTTTG
  GCAGTGAGCTCAGCCTGGTGTATGTGCCCTCTGTGCTGGAGAAGCTGGACTGAGCGCAGG
  GCCTCCTTGCCCAGGCAGGAGGCTGGGGTGCTGTGTGGGGGCCAATGCACTGAACCTGGA
  CTTGGGGGAAAGAGCCGAGTATCTTCCAGCCGCTGCCTCCTGACTGTAATAATATTAAAC
  TTTTTTAAAAAACCATAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for XM_033294 unedited
  TTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTGATCCATGGTCACTTT
  CCGGGATGGCAGCAAGGTGACTTCGGCTGAGGATGACCCTGACTGAAAGGCTGCGTGAGA
  AGATATCTCGGGCCTTCTACAACCATGGGCTCCTCTGTGCATCCTATCCCATCCCCATCA
  TCCTCTTCACAGGGTTCTGCATCTTAGCCTGCTGCTACCCACTGCTGAAACTCCCCTTGC
  CAGGAACAGGACCTGTGGAATTCACCACCCCTGTGAAGGATTACTCGCCCCCACCTGTGG
  ACTCTGACCGCAAACAAGGAGAGCCTACTGAGCAGCCTGAGTGGTATGTGGGTGCCCCGG
  TGGCTTATGTCCAGCAGATATTTGTGAAGTCCTCAGTGTTTCCCTGGCACAAGAACCTCC
  TGGCAGTAGATGTATTTCGTTCACCTTTGTCCCGGGCATTCCAACTGGTGGAGGAGATCC
  GGAACCACGTGCTGAGAGACAGCTCTGGGATCAGGAGCTTGGAGGAGTTGTGTCTGCAAG
  TGACCGACCTGCTGCCAGGCCTTAGGAAGCTCAGGAACCTACTCCCTGAGCATGGATGCC
  TGCTGCTGTCCCCTGGGAACTTCTGGCAGAATGACTGGGAACGCTTCCATGCTGATCCTG
  ACATCATTGGGACCATCCACCAGCACGAGCCTAAAACCCTGCAGACTTCAGCCACACTCA
  AAGACTTGTTATTTGGNTGTTCCTGGGAAGTACAGCGGGGGTGAGCCCTCTACACCAGGA
  AGAGGGATGGGTCTNCTACACCATCACCCTGGTCTTCCAGCACTACCATGCCAAGTTCCT
  GGGCAGNCTGCGTGCCCGCCTGATGCTTNTGCACCCCACCCCACTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for XM_033294 unedited
  ATGCACCGCGGTTCGTTATCTAGAGTCGAGGTTTTTTTTTTTTTTTTTTTTTTTCCCTTT
  TTTTTTTTTTTTTTTTTTTTTTTTAGGGGTTTTTAAAAAAGTTTAATTTTTTACAGCCCG
  GAGGCCCCGGTTGGAAAATACTTCGGTTTTTTTCCCTAATTTCAGGTTAAGGGGATGGGC
  CCCCACACAGAACCCCAGCCTCCTGCCTGGGCAAGGAGGGCTTGGGCTAAACCCAGTTTC
  TCCAGCACAGAGGGCACACACACCAGGCTGAGGTTATTGTAAAAGTTGTAAACAATGGCA
  GGGTGGCCCAACACCAGGATCTGGGGGGCAGGCTGGGCCTAAATGGTCTCTCTCATTTAA
  TATGCCTTGAAAAGGTCCTCGAAGTTTAGGCTCCAAAAGGAAACCCAGGCCTGGGCGGGA
  ATAATAAAAATGCCTCCGGGAGAACAACCCCCACCCGCGCGCACATTCTAAGTCTCGCTG
  AAAGAAATTACAATTCACCCCCTTTCTCCCCTCCCCATTTTTCCCGAAGTTTTTCATTTC
  CCCCTCAAATTCAATAAGCGCGACAGGTCCGCCACGTCACCCTTCCCGTTTCCCCCCATT
  TGTCCCCCCCCTCCCCCCCCACCCCCCCCGGGAATGGCCCCATTTTCCCCACACTGCCCC
  CCCCAATGTTCGTTATTTGTCCTTTTTTACCATCCCATATGGCCGGCCGCACCGGCGCGC
  CCCGCATCCTTATCGCCTCTCCCCCACCCCCTCTCTACCATCCTCCCCCTTTTATCCCCC
  ACCTGCCCCCCTTTGTCTATCCGGCCCGTGACATTTACCACATACCACACCCCCACCCAT
  TCCCGCCCGCGACCGCCAACGAGGTAAGGCGGGTGATAATGTTATCCCATCACCCGCCTA
  CCCTTATTTTTTCTTTCCCGCCCTTGTTCGGTCCGCCCAACTCCCTATCCCCACCCTCCT
  TCCCATCCACGGCGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012235
• ORF Size: 3840 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: It is not a varient.

Reference Data

• RefSeq: NM_012235.2, NP_036367.2
• RefSeq Size: 4255
• RefSeq ORF: 3840
• Locus ID: 22937
• Domains: WD40
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).