CDC14B (NM_001077181) Human Untagged Clone

CAT#: SC315434

CDC14B (untagged)-Human CDC14 cell division cycle 14 homolog B (S. cerevisiae) (CDC14B), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC14B
• Synonyms: Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001077181, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCCGGGAGGGCGCGGGGGCAGCTTTGGTAGCCGAGGTGATCAAAGATCGCCTTTGTTTTGCCATTC
  TCTACAGCAGACCAAAGAGTGCATCAAATGTACATTATTTCAGCATAGATAATGAACTTGAATATGAGAA
  CTTCTACGCAGATTTTGGACCACTCAATCTGGCAATGGTTTACAGATATTGTTGCAAGATCAATAAGAAA
  TTAAAGTCCATTACAATGTTAAGGAAGAAAATTGTTCATTTTACTGGCTCTGATCAGAGAAAACAAGCAA
  ATGCTGCCTTCCTTGTTGGATGCTACATGGTTATATATTTGGGGAGAACCCCAGAAGAAGCATATAGAAT
  ATTAATCTTTGGAGAGACATCCTATATTCCTTTCAGAGATGCTGCCTATGGAAGTTGCAATTTCTACATT
  ACACTTCTTGACTGTTTTCATGCAGTAAAGAAGGCAATGCAGTATGGCTTCCTTAATTTCAACTCATTTA
  ACCTTGATGAATATGAACACTATGAAAAAGCAGAAAATGGAGATTTAAATTGGATAATACCAGACCGATT
  TATTGCCTTCTGTGGACCTCATTCAAGAGCCAGACTTGAAAGTGGTTACCACCAACATTCTCCTGAGACT
  TATATTCAATATTTTAAGAATCACAATGTTACTACCATTATTCGTCTGAATAAAAGGATGTATGATGCCA
  AACGCTTTACGGATGCTGGCTTCGATCACCATGATCTTTTCTTTGCGGATGGCAGCACCCCTACTGATGC
  CATTGTCAAAGAATTCCTAGATATCTGTGAAAATGCTGAGGGTGCCATTGCAGTACATTGCAAAGCTGGC
  CTTGGTCGCACGGGCACTCTGATAGCCTGCTACATCATGAAGCATTACAGGATGACAGCAGCCGAGACCA
  TTGCGTGGGTCAGGATCTGCAGACCTGGCTCGGTGATTGGGCCTCAGCAGCAGTTTTTGGTGATGAAGCA
  AACCAACCTCTGGCTGGAAGGGGACTATTTTCGTCAGAAGTTAAAGGGGCAGGAGAATGGACAACACAGA
  GCAGCCTTCTCCAAACTTCTCTCTGGCGTTGATGACATTTCCATAAATGGGGTCGAGAATCAAGATCAGC
  AAGAACCCGAACCGTACAGTGATGATGACGAAATCAATGGAGTGACACAAGGTGATAGACTTCGGGCCTT
  GAAAAGCAGAAGACAATCCAAAACAAACGCTATTCCTCTCACAGTAATTCTTCAATCCAGTGTTCAGAGC
  TGTAAAACATCTGAACCTAACATTTCTGGCAGTGCAGGCATTACTAAAAGAACCACCAGATCTGCTTCAA
  GGAAAAGCAGTGTTAAAAGTCTCTCCATTTCAAGGACTAAAACAGTCTTGCGTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001077181
• ORF Size: 1386 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001077181.1, NP_001070649.1
• RefSeq Size: 5131
• RefSeq ORF: 1386
• Locus ID: 8555
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Cell cycle
• Gene Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) has an alternate 5' exon, compared to variant 2, resulting in a protein (isoform 3) that has an alternate N-terminus, compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.