TrkA (NTRK1) (NM_002529) Human Untagged Clone

CAT#: SC315454

NTRK1 (untagged)-Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2


  "NM_002529" in other vectors (7)

Reconstitution Protocol

USD 1,610.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "NTRK1"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NTRK1
Synonyms MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_002529 edited
ATGCTGCGAGGCGGACGGCGCGGGCAGCTTGGCTGGCACAGCTGGGCTGCGGGGCCGGGC
AGCCTGCTGGCTTGGCTGATACTGGCATCTGCGGGCGCCGCACCCTGCCCCGATGCCTGC
TGCCCCCACGGCTCCTCGGGACTGCGATGCACCCGGGATGGGGCCCTGGATAGCCTCCAC
CACCTGCCCGGCGCAGAGAACCTGACTGAGCTCTACATCGAGAACCAGCAGCATCTGCAG
CATCTGGAGCTCCGTGATCTGAGGGGCCTGGGGGAGCTGAGAAACCTCACCATCGTGAAG
AGTGGTCTCCGTTTCGTGGCGCCAGATGCCTTCCATTTCACTCCTCGGCTCAGTCGCCTG
AATCTCTCCTTCAACGCTCTGGAGTCTCTCTCCTGGAAAACTGTGCAGGGCCTCTCCTTA
CAGGAACTGGTCCTGTCGGGGAACCCTCTGCACTGTTCTTGTGCCCTGCGCTGGCTACAG
CGCTGGGAGGAGGAGGGACTGGGCGGAGTGCCTGAACAGAAGCTGCAGTGTCATGGGCAA
GGGCCCCTGGCCCACATGCCCAATGCCAGCTGTGGTGTGCCCACGCTGAAGGTCCAGGTG
CCCAATGCCTCGGTGGATGTGGGGGACGACGTGCTGCTGCGGTGCCAGGTGGAGGGGCGG
GGCCTGGAGCAGGCCGGCTGGATCCTCACAGAGCTGGAGCAGTCAGCCACGGTGATGAAA
TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGG
AAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTC
AACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC
ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCC
GTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCCGCAGCCAATGAGACC
GTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG
CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGAC
AACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGTCTCCTTCTCGCCGGTGGACACT
AACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTG
GCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAAC
AAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGAT
GGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAG
GGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCC
TGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCC
TTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTG
GTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAG
GCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACC
GAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTC
CTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGC
CCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTAC
CTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAG
GGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTAT
TACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTG
TACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATC
TTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATC
ACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATG
CGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGG
CTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTGGGCTAG
>Reverse primer walk for NM_002529 unedited
GGGGNCCCACTACGTTCGTGCCCCCACTNCCACCGNAGNNCATTGGGCACCTGGNACCTT
CAGCGTGGGCACACCACAGCTGGCATTGGGCATGTGGGCCAGGGGCCCTTGCCCATGACA
CTGCAGCTTCTGTTCAGGCACTCCGCCCAGTCCCTCCTCCTCCCAGCGCTGTAGCCAGCG
CAGGGCACAAGAACAGTGCAGAGGGTTCCCCGACAGGACCAGTTCCTGTAAGGAGAGGCC
CTGCACAGTTTTCCAGGAGAGAGACTCCAGAGCGTTGAAGGAGAGATTCAGGCGACTGAG
CCGAGGAGTGAAATGGAAGGCATCTGGCGCCACGAAACGGAGACCACTCTTCACGATGGT
GAGGTTTCTCAGCTCCCCCAGGCCCCTCAGATCACGGAGCTCCAGATGCTGCAGATGCTG
CTGGTTCTCGATGTAGAGCTCAGTCAGGTTCTCTGCGCCGGGCAGGTGGTGGAGGCTATC
CAGGGCCCCATCCCGGGTGCATCGCAGTCCCGAGGAGCCGTGGGGGCAGCAGGCATCGGG
GCAGGGTGCGGCGCCCGCAGATGCCAGTATCAGCCAAGCCAGCAGGCTGCCCGGCCCCGC
AGCCCAGCTGTGCCAGCCAAGCTGCCCGCGCCGTCCGCCTCGCAGCATGCGGCCGCCCTA
TAGTGAGTCGTATTACANAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCT
CCCACCGTACACGCCCTACCGCCCATTTGCGTCAACGGGGCGGGGTTATTACGACATTTT
GGGAAAGTCCCCGTGATTTTTGGTGCCAAAACAAACTNCCATTGGACGTCATGGGTTGGA
GACTTGGAAATCCCCGTGAGTCAAACCGCTATCCAGCCCCATTGGTGTACTGCCCAAACC
GATCAACCTGGTAATAGCGA
>OriGene 3' read for NM_002529 unedited
GGCAATGGGGAGGCAACTTCCAGGCCAGNATAGCACTGGGGAGGGTACAGGGATGCCCCC
GGGACGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGAGCGTCACGAGCTAGCCCAG
GACATCCAGGTAGACAGGAGGTGCCTGGGCCAGGGCTTGCAGCCGGGCGTGCACATCCTT
GATGCTGTGGCGTTGCTGGGGCTCCCGCTGCCAGCAGCCCCGCATGATGGCGTAGACCTC
TGGTGGGCAGGCACGTGGCCGCTCCAACTCACGTCCCTGCGTGATGCAGTCGATTGCCTC
CGTGTTGGAGAGCTGGTACCAGGGCTGCTTGCCGTAGGTGAAGATCTCCCAGAGCACCAC
GCCGAAGCTCCACACGTCGCTCTCGGTGGTGAACTTACGGTACAGGATGCTCTCGGGCGG
CATCCAGCGAATGGGCAGCATGGTGCGGCCTCCCACACGGTAATAGTCGGTGCTGTAGAT
ATCCCTGCTCATGCCAAAATCACCAATCTTGACCCACCAGTCCCTGNCCCACTAGACAGT
TTGCGTGTGGCCAGGTCCCGGTGCACANAATGCAGACCCGCCAGGTACACCATCCCCGCA
GCGACCTGGCTAGCCANCGGGGGGCNAGCACCTGCCCAAACCCAGGGGGCCTGGACCCCC
ATTCTCCCCACAACCAAAACTTGGAATTAGTCCATGGAATCNNNNNAAGAAAAAAAAACC
CCTTTGTAGTCCCCTCTGGCCGCCATTTCTCTAAAAACTATAGCCGGGGGGGGCCCCTCT
TGGGCCAACCCCCCAAAAACCCCCAAGTGTGTTGGTTTTCCCCCGTGGGAAAAACCCCCA
CCCCCCCCCCGGAAAATCCTGGGAAAAACTTTTGGGACCCTCTTTTTTTTGG
Restriction Sites Please inquire     
ACCN NM_002529
Insert Size 2400 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002529.3, NP_002520.2
RefSeq Size 2663 bp
RefSeq ORF 2391 bp
Locus ID 4914
Cytogenetics 1q23.1
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Apoptosis, Endocytosis, MAPK signaling pathway, Neurotrophin signaling pathway, Pathways in cancer, Thyroid cancer
Gene Summary 'This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2).

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.