PKD1L2 (NM_001076780) Human Untagged Clone

CAT#: SC315457

PKD1L2 (untagged)-Human polycystic kidney disease 1-like 2 (PKD1L2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PKD1L2
• Synonyms: PC1L2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001076780, the custom clone sequence may differ by one or more nucleotides
  ATGAGTGCAGTGGGCTTGGTACTCCTGGTGCTTGCTCTGAGGCTTAGGGCCACCACTGTT
  AAGCCAGAGGAAGGCAGCTTTTGCTCTAACAGCCAGGTGGCCTTCAGAGATGCTTGCTAT
  GAATTTGTGCCACTCGGACGCACCTTCCGTGATGCCCAGAGCTGGTGCGAGGGGCAAGGA
  GGCCATTTGGTCTTCATTCAGGACGAAGGCACCCAGTGGTTTCTGCAGAAGCACATCTCC
  CAGGACAGGGAATGGTGGATTGGACTCACGTGGAACTTGGCACGGAATGGAACCACGGAG
  GGGCCGGGGACTTGGTTGGACACCTCCAATGTGACCTACAGCAACTGGCATGGAGGGCAG
  GCCGCCGCTGCCCCTGACACCTGCGGCCACATCGGGAGAGGCCCTTCCTCTGAGTGGGTG
  ACCTCGGACTGCGCCCAGACCTTCGCCTTCATGTGCGAGTTCCGGGTTGGCCAGAGCCTG
  GCCTGCGAGGGACTCAATGCCACCGTGCACTGTGGCTTGGGGCAGGTCATCCAGGTCCAG
  GATGCCGTCTACGGGCGCCAGAATCCCCATTTCTGCACCCAGGATGCCGGGCGTCCTTCA
  GATCTGGAGCAGGGATGCAGCTGGGCCAACGTCAAGGAGGAGGTGGCAGGCCAGTGCCAG
  GAGCTACAGTCATGCCAGGTGGCAGCAGATGAGACCTACTTTGGAAACCTGTGTCCGACT
  CAGGGCAGTTACCTGTGGGTGCAGTACCAGTGCCGGGAAGCCCTGCAGCTGATGGTGTCC
  AGTGAGAGTTTCATCTTTGACAATGTCACCATCTCCCTGACGTGGCTCCTCTCACCCTAC
  ATAGGAAACCTGTCCTGTATAATTAGTACAGGAGACAGCCACACTTTTGATCCCTACAAC
  CCGCCGAGTGTGTCCAGCAATGTGACCCACCAGTTCACATCTCCTGGGGAATTCACCGTG
  TTTGCTGAATGCACAACCAGTGAGTGGCATGTGACAGCTCAGAGGCAGGTGACCGTGCGA
  GACAAGATGGAGACGCTCAGTGTGACTGCATGCTCCGGCCTGTCCCAGTCAGGAGCCGGC
  CCTCTCTGCCAGGCTGTCTTTGGGGATCCTCTGTGGATTCAGGTGGAGCTTGATGGAGGA
  ACAGGAGTGACTTACACTGTGCTTTTGGGTGACATAACCCTGGCCGAGTCCACCACCCAA
  AAGGGCTCGCTACCGTACAATCTGATCCTGGACAGAGAAACCCAGAAACTGATGGGCCCT
  GGGAGGCACCGCCTGGAGATCCAAGCCACCGGCAACACCACCACCTCTACAATCTCCAGA
  AACATTACAGTCCACTTGGTGGAGCTGCTGTCAGGGCTGCAGGCCTCCTGGGCTTCTGAC
  CATTTGGAGCTTGGACAGGACCTATTGATCACCATCTCATTGGCTCAGGGCACCCCGGAA
  GAGCTGACCTTTGAGGTGGCTGGACTCAATGCAACCTTCTCCCACGAGCAAGTGAGCTTT
  GGAGAGCCATTTGGGATTTGCCGCCTGGCTGTTCCGGTTGAAGGCACCTTTCTGGTCACC
  ATGCTGGTGAGGAATGCCTTCTCCAACCTGAGTTTGGAAATCGGGAACATCACTATCACA
  GCCCCTTCCGGTCTCCAAGAACCATCTGGGATGAATGCTGAAGGAAAGAGTAAAGATAAA
  GGCGATATGGAGGTGTACATCCAACCTGGTCCATATGTGGATCCTTTCACGACAGTGACC
  CTGGGCTGGCCAGACAATGACAAGGAGTTACGCTTCCAATGGTCATGTGGGTCTTGCTGG
  GCTCTGTGGAGCAGCTGTGTTGAGAGGCAGCTGCTTCGCACAGACCAGAGGGAGCTGGTG
  GTTCCAGCATCCTGCCTGCCGCCGCCTGACTCTGCTGTCACCCTGCGCCTGGCTGTTCTG
  AGAGGCCAAGAGCTGGAGAACAGGGCAGAGCAGTGCCTCTACGTGTCTGCGCCCTGGGAA
  CTCAGGCCTCGAGTCAGCTGTGAGAGGAACTGCAGGCCAGTTAATGCCAGCAAAGACATT
  CTGCTCAGGGTCACCATGGGGGAGGACTCTCCAGTGGCTATGTTCAGCTGGTATTTGGAC
  AACACCCCAACAGAGCAGGCTGAGCCCCTCCTGGATGCCTGCAGACTCAGAGGATTTTGG
  CCAAGGTCCTTAACCCTCCTCCAGAGCAACACCTCCACGTTGCTGTTGAACAGCTCGTTT
  CTGCAGTCCCGGGGAGAGGTCATCCGAATCAGAGCCACAGCACTGACCAGGCATGCCTAT
  GGGGAGGACACCTATGTGATCAGCACTGTGCCTCCCCGTGAGGTGCCTGCCTGCACTATT
  GCCCCAGAGGAGGGCACCGTTCTGACGAGCTTTGCCATCTTCTGCAACGCCTCCACAGCC
  CTGGGACCCCTGGAGTTCTGCTTCTGTCTGGAATCAGGTTCCTGCCTACACTGTGGCCCT
  GAACCTGCCCTCCCATCAGTGTATCTGCCACTTGGAGAGGAGAACAATGACTTTGTGCTG
  ACAGTAGTTATTTCTGCCACCAATCGTGCAGGGGACACGCAGCAGACCCAGGCCATGGCT
  AAGGTGGCACTCGGAGACACATGTGTTGAGGATGTAGCATTCCAGGCTGCCGTGTCAGAG
  AAAATCCCCACAGCTCTGCAAGGCGAGGGTGGCCCCGAGCAGCTCCTCCAGCTGGCCAAG
  GCTGTGTCCTCCATGCTGAACCAAGAGCATGAAAGCCAGGGCTCAGGACAGTCACTGAGC
  ATAGACGTCAGACAGAAGGTCAGAGAGCATGTGCTGGGATCACTGTCTGCAGTCACCACC
  GGCTTGGAGGACGTGCAGAGGGTGCAGGAGCTGGCCGAGGTGCTGAGAGAGGTGACCTGC
  CGGAGTAAGGAACTCACACCCTCGGCCCAGGGGTCCTGCATGGGCGATTCATGGGAAGGT
  GCCCCTCCTGCTGCCCATGTATCTCACGCTAGG
  
• Restriction Sites: Please inquire
• ACCN: NM_001076780
• ORF Size: 2976 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001076780.1, NP_001070248.1
• RefSeq Size: 3427
• RefSeq ORF: 2976
• Locus ID: 114780
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, and the reference genome encodes a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2019]
  Transcript Variant: This variant (3) lacks several 3' exons but includes an alternate 3' exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) is shorter and has a distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.