Kallikrein 5 (KLK5) (NM_001077492) Human Untagged Clone

CAT#: SC315512

KLK5 (untagged)-Human kallikrein-related peptidase 5 (KLK5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLK5
• Synonyms: KLK-L2; KLKL2; SCTE
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001077492, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTACAGCAAGACCCCCCTGGATGTGGGTGCTCTGTGCTCTGATCACAGCCTTGCTTCTGGGGGTCA
  CAGAGCATGTTCTCGCCAACAATGATGTTTCCTGTGACCACCCCTCTAACACCGTGCCCTCTGGGAGCAA
  CCAGGACCTGGGAGCTGGGGCCGGGGAAGACGCCCGGTCGGATGACAGCAGCAGCCGCATCATCAATGGA
  TCCGACTGCGATATGCACACCCAGCCGTGGCAGGCCGCGCTGTTGCTAAGGCCCAACCAGCTCTACTGCG
  GGGCGGTGTTGGTGCATCCACAGTGGCTGCTCACGGCCGCCCACTGCAGGAAGAAAGTTTTCAGAGTCCG
  TCTCGGCCACTACTCCCTGTCACCAGTTTATGAATCTGGGCAGCAGATGTTCCAGGGGGTCAAATCCATC
  CCCCACCCTGGCTACTCCCACCCTGGCCACTCTAACGACCTCATGCTCATCAAACTGAACAGAAGAATTC
  GTCCCACTAAAGATGTCAGACCCATCAACGTCTCCTCTCATTGTCCCTCTGCTGGGACAAAGTGCTTGGT
  GTCTGGCTGGGGGACAACCAAGAGCCCCCAAGTGCACTTCCCTAAGGTCCTCCAGTGCTTGAATATCAGC
  GTGCTAAGTCAGAAAAGGTGCGAGGATGCTTACCCGAGACAGATAGATGACACCATGTTCTGCGCCGGTG
  ACAAAGCAGGTAGAGACTCCTGCCAGGGTGATTCTGGGGGGCCTGTGGTCTGCAATGGCTCCCTGCAGGG
  ACTCGTGTCCTGGGGAGATTACCCTTGTGCCCGGCCCAACAGACCGGGTGTCTACACGAACCTCTGCAAG
  TTCACCAAGTGGATCCAGGAAACCATCCAGGCCAACTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001077492
• ORF Size: 882 bp
• Insert Size: 0
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001077492.1, NP_001070960.1
• RefSeq Size: 1367
• RefSeq ORF: 882
• Locus ID: 25818
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• Gene Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants encode the same protein.