UBXD5 (UBXN11) (NM_001077262) Human Untagged Clone

CAT#: SC315546

UBXN11 (untagged)-Human UBX domain protein 11 (UBXN11), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBXN11
• Synonyms: COA-1; PP2243; SOC; SOCI; UBXD5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001077262, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCTCACCTTTGGCCTCCCTTAGCAAGACCCGAAAAGTGCCCCTGCCCTCGGAGCCTATGAATCCTG
  GGAGGCGAGGAATCCGCATCTATGGAGATGAAGATGAGGTGGACATGTTGAGTGATGGGTGTGGCTCAGA
  AGAAAAGATCTCAGTCCCTTCCTGCTATGGCGGCATAGGTGCCCCTGTGAGTCGGCAAGGGGACTCATTG
  GCGCCCCCTGAGGTGGACTTTGACAGGCTGCTGGCCAGCCTGCAGGATCTTAGTGAGCTGGTGGTAGAGG
  GTGACACCCAAGTGACACCAGTGCCCGGCGGGGCACGGCTGCGTACCCTCGAGCCCATCCCGCTGAAGCT
  CTACCGGAATGGCATCATGATGTTCGACGGGCCCTTCCAGCCCTTCTACGATCCCTCCACACAGCGCTGC
  CTCCGAGACATATTGGATGGCTTCTTTCCCTCAGAGCTCCAGCGACTGTACCCCAATGGGGTCCCCTTTA
  AGGTGAGTGACTTGCGCAATCAGGTCTACCTGGAGGATGGACTGGACCCCTTCCCAGGCGAGGGCCGTGT
  GGTGGGCAGGCAGCTGATGCACAAGGCCTTGGACAGGGTGGAGGAGCACCCAGGCTCCAGGATGACTGCT
  GAGAAATTTCTGAACAGGCTCCCCAAGTTTGTGATCCGGCAAGGCGAGGTGATTGACATCCGGGGCCCCA
  TCAGGGACACCTTGCAGAACTGCTGCCCATTGCCTGCCCGGATCCAGGAGATTGTGGTGGAGACGCCCAC
  CTTGGCCGCTGAGCGAGAGAGGAGCCAGGAGTCACCCAACACGCCGGCACCCCCGCTCTCCATGCTGCGC
  ATCAAGTCTGAGAATGGGGAACAGGCCTTCCTACTGATGATGCAGCCTGACAACACCATTGGGGACGTGC
  GAGCTCTGCTAGCGCAGGCCAGGGTCATGGATGCCTCTGCCTTTGAGATCTTCAGCACATTCCCGCCCAC
  CCTCTACCAGGACGATACACTCACGCTGCAGGCTGCAGGCCTTGTGCCCAAAGCAGCACTGCTGCTGCGG
  GCACGCCGAGCCCCGAAGTCCAGCCTGAAATTCAGTCCTGGTCCCTGTCCCGGTCCCGGTCCCGGCCCCA
  GTCCCGGTCCCGGTCCCGGCCCCAGTCCCGGTCCCGGTCCCGGCCCCAGTCCCTGTCCTGGACCCAGTCC
  CAGCCCCCAATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001077262
• ORF Size: 1203 bp
• Insert Size: 0
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001077262.1, NP_001070730.1
• RefSeq Size: 1384
• RefSeq ORF: 1203
• Locus ID: 91544
• Gene Summary: This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame group of four exons in the coding region, compared to variant 2. The resulting protein (isoform 3) is shorter than isoform 2.