POMT1 (NM_001077366) Human Untagged Clone

CAT#: SC315608

POMT1 (untagged)-Human protein-O-mannosyltransferase 1 (POMT1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POMT1
• Synonyms: LGMD2K; LGMDR11; MDDGA1; MDDGB1; MDDGC1; RT
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001077366, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAACAAATCTTCTTCTTGGATGACAGTGGGCCGCCATTTGGCCACATGGTGCTGGCCTTGGGAGGTT
  ATTTAGGAGGATTCGATGGCAATTTTTTGTGGAACAGAATTGGAGCAGAATACAGTAGCAACGTGCCTGT
  GTGGTCCCTGCGCCTGCTGCCAGCACTCGCGGGGGCCTTGTCGGTCCCCATGGCCTACCAGATAGTGTTG
  GAGCTCCACTTTTCTCATTGTGCCGCCATGGGAGCTGCTCTGTTGATGCTTATCGAGAATGCTCTCATCA
  CTCAGTCAAGGCTAATGCTTTTGGAATCAGTGTTAATATTTTTCAATCTATTGGCCGTGTTGTCCTACCT
  GAAGTTCTTCAACTGCCAAAAGCACAGCCCTTTTTCTCTGAGCTGGTGGTTCTGGCTAACACTGACAGGG
  GTCGCTTGTTCCTGTGCAGTGGGCATCAAGTACATGGGTGTGTTCACGTACGTGCTCGTGCTGGGTGTTG
  CAGCTGTCCATGCCTGGCACCTGCTTGGAGACCAGACTTTGTCCAATGTCTGTGTGTTCTGTCACTTGCT
  CGCCCGAGCAGTGGCTTTGCTGGTCATCCCGGTCGTCCTGTACTTACTGTTCTTCTACGTCCACTTGATT
  CTAGTCTTCCGCTCTGGGCCCCACGACCAAATCATGTCCAGTGCCTTCCAGGCCAGCTTAGAGGGAGGAC
  TAGCTCGGATCACCCAGGGTCAGCCACTGGAGGTGGCCTTTGGGTCCCAGGTCACTCTGAGGAACGTCTT
  TGGGAAACCTGTGCCCTGCTGGCTTCATTCCCACCAGGACACCTACCCCATGATATATGAGAACGGCCGA
  GGCAGCTCCCACCAGCAACAGGTGACCTGTTACCCCTTCAAAGACGTCAATAACTGGTGGATTGTAAAGG
  ATCCCAGGAGGCACCAGCTGGTGGTGAGCAGCCCTCCGAGACCTGTGAGGCACGGGGACATGGTGCAGCT
  GGTCCACGGCATGACCACCCGCTCCCTGAACACGCATGATGTTGCAGCCCCCCTGAGCCCCCATTCACAG
  GAGGTCTCCTGCTACATTGACTATAACATCTCCATGCCCGCCCAGAACCTCTGGAGACTGGAAATTGTGA
  ACAGAGGATCTGACACAGACGTCTGGAAGACCATCCTCTCAGAGGTCCGCTTTGTGCACGTGAACACTTC
  CGCTGTCTTAAAGCTGAGCGGGGCTCACCTCCCTGACTGGGGGTATCGGCAACTGGAGATCGTCGGGGAG
  AAGCTGTCCCGGGGCTACCACGGGAGCACGGTGTGGAACGTGGAGGAGCACCGATACGGCGCGAGCCAGG
  AGCAGAGGGAGCGGGAACGGGAGCTGCACTCACCTGCGCAGGTGGACGTCAGCAGGAACCTCAGCTTCAT
  GGCGAGATTCTCGGAGCTGCAGTGGAGGATGCTGGCGCTGAGAAGTGATGACTCGGAACACAAGTACAGC
  TCCAGCCCACTGGAGTGGGTCACCCTGGACACCAATATTGCCTACTGGCTGCACCCCAGGACCAGCGCTC
  AGATCCACCTACTTGGAAACATAGTGATCTGGGTTTCGGGCAGCCTCGCTCTGGCCATCTACGCCCTGCT
  GTCCTTGTGGTACCTGCTCCGACGGCGAAGAAATGTCCATGACCTCCCTCAGGATGCCTGGCTGCGCTGG
  GTGCTGGCTGGGGCGCTGTGTGCCGGTGGCTGGGCAGTGAACTACCTCCCGTTCTTCCTGATGGAGAAGA
  CACTCTTCCTCTACCACTACCTGCCCGCACTCACCTTCCAAATCCTTCTGCTCCCTGTGGTCCTGCAGCA
  CATCAGCGACCACCTGTGCAGGTCCCAGCTCCAGAGGAGCATCTTCAGCGCCCTGGTGGTGGCCTGGTAC
  TCCTCCGCGTGCCACGTGTCCAACACGCTGCGCCCACTCACCTACGGGGACAAGTCACTCTCGCCACATG
  AACTCAAGGCCCTTCGCTGGAAAGACAGCTGGGACATCTTGATCCGAAAACACTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001077366
• ORF Size: 2016 bp
• Insert Size: 0
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001077366.1, NP_001070834.1
• RefSeq Size: 2928
• RefSeq ORF: 2016
• Locus ID: 10585
• Protein Families: Transmembrane
• Protein Pathways: O-Mannosyl glycan biosynthesis
• Gene Summary: The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (3) uses an alternate in-frame splice site and lacks the exon containing the translation start site compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks an internal segment compared to isoform a. Variants 3 and 7 both encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.