POMT1 (NM_001077365) Human Untagged Clone

CAT#: SC315615

POMT1 (untagged)-Human protein-O-mannosyltransferase 1 (POMT1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POMT1
• Synonyms: LGMD2K; LGMDR11; MDDGA1; MDDGB1; MDDGC1; RT
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001077365 edited
  GCGGAGTGCCGAGCGGCCTCACCCCCAACCGTCGGCCCAGTCGGACGGTTCCGAGGCGTT
  GCCGGGAGCCGGGCGCGGCTCTGTGTGGACTCGGAGAAACGCGGGGCGTCTGCCTGAGCC
  CGCTTTTCTACAAGATGTGGGGATTTTTGAAGCGCCCTGTAGTGGTGACGGCTGACATCA
  ACTTGAGCCTTGTGGCCCTGACTGGGATGGGGTTACTGAGCCGGCTGTGGCGACTCACCT
  ACCCGCGGGCTGTGGTTTTTGACGAAGTATATTATGGGCAGTACATCTCTTTTTACATGA
  AACAAATCTTCTTCTTGGATGACAGTGGGCCGCCATTTGGCCACATGGTGCTGGCCTTGG
  GAGGTTATTTAGGAGGATTCGATGGCAATTTTTTGTGGAACAGAATTGGAGCAGAATACA
  GTAGCAACGTGCCTGTGTGGTCCCTGCGCCTGCTGCCAGCACTCGCGGGGGCCTTGTCGG
  TCCCCATGGCCTACCAGATAGTGTTGGAGCTCCACTTTTCTCATTGTGCCGCCATGGGAG
  CTGCTCTGTTGATGCTTATCGAGAATGCTCTCATCACTCAGTCAAGGCTAATGCTTTTGG
  AATCAGTGTTAATATTTTTCAATCTATTGGCCGTGTTGTCCTACCTGAAGTTCTTCAACT
  GCCAAAAGCACAGCCCTTTTTCTCTGAGCTGGTGGTTCTGGCTAACACTGACAGGGGTCG
  CTTGTTCCTGTGCAGTGGGCATCAAGTACATGGGTGTGTTCACGTACGTGCTCGTGCTGG
  GTGTTGCAGCTGTCCATGCCTGGCACCTGCTTGGAGACCAGACTTTGTCCAATGTCTGTG
  TGTTCTGTCACTTGCTCGCCCGAGCAGTGGCTTTGCTGGTCATCCCGGTCGTCCTGTACT
  TACTGTTCTTCTACGTCCACTTGATTCTAGTCTTCCGCTCTGGGCCCCACGACCAAATCA
  TGTCCAGTGCCTTCCAGGCCAGCTTAGAGGGAGGACTAGCTCGGATCACTCAGGGTCAGC
  CACTGGAGGTGGCCTTTGGGTCCCAGATCACTCTGAGGAACGTCTTTGGGAAACCTGTGC
  CCTGCTGGCTTCATTCCCACCAGGACACCTACCCCATGATATATGAGAACGGCCGAGGCA
  GCTCCCACCAGCAACAGGTGACCTGTTACCCCTTCAAAGATGTCAATAACTGGTGGATTG
  TAAAGGATCCCAGGAGGCACCAGCTGGTGGTGAGCAGCCCTCCGAGACCTGTGAGGCACG
  GGGACATGGTGCAGCTGGTCCACGGCATGACCACCCGCTCCCTGAACACGCATGATGTTG
  CAGCCCCCCTGAGCCCCCATTCACAGGAGGTCTCCTGCTACATTGACTATAACATCTCCA
  TGCCCGCCCAGAACCTCTGGAGACTGGAAATTGTGAACAGAGGATCTGACACAGACGTCT
  GGAAGACCATCCTCTCAGAGGTCCGCTTTGTGCACGTGAACACTTCCGCTGTCTTAAAGC
  TGAGCGGGGCTCACCTCCCTGACTGGGGGTATCGGCAACTGGAGATCGTCGGGGAGAAGC
  TGTCCCGGGGCTACCACGGGAGCACGGTGTGGAACGTGGAGGAGCACCGATACGGCGCGA
  GCCAGGAGCAGAGGGAGCGGGAACGGGAGCTGCACTCACCTGCGCAGGTGGACGTCAGCA
  GGAACCTCAGCTTCATGGCGAGATTCTCGGAGCTGCAGTGGAGGATGCTGGCGCTGAGAA
  GTGATGACTCGGAACACAAGTACAGCTCCAGCCCACTGGAGTGGGTCACCCTGGACACCA
  ATATTGCCTACTGGCTGCACCCCAGGACCAGCGCTCAGATCCACCTACTTGGAAACATAG
  TGATCTGGGTTTCGGGCAGCCTCGCTCTGGCCATCTACGCCCTGCTGTCCTTGTGGTACC
  TGCTCCGACGGCGAAGAAATGTCCATGACCTCCCTCAGGATGCCTGGCTGCGCTGGGTGC
  TGGCTGGGGCGCTGTGTGCCGGTGGCTGGGCAGTGAACTACCTCCCGTTCTTCCTGATGG
  AGAAGACACTCTTCCTCTACCACTACCTGCCCGCACTCACCTTCCAAATCCTTCTGCTCC
  CTGTGGTCCTGCAGCACATCAGCGACCACCTGTGCAGGTCCCAGCTCCAGAGGAGCATCT
  TCAGCGCCCTGGTGGTGGCCTGGTACTCCTCCGCGTGCCACGTGTCCAACACGCTGCGCC
  CACTCACCTACGGGGACAAGTCACTCTCGCCACATGAACTCAAGGCCCTTCGCTGGAAAG
  ACAGCTGGGACATCTTGATCCGAAAACACTAGAACAAGAGTGTGGCAAAGAACACCCGTG
  CTGGGGTCGGGATGAGGTTGAAGGGTCTTGGTCAATGTACGTAATGAGCAGGGTGGGCCC
  CACGCTGGGAGGACACGGGCTGGGCTGAGCAGGGCCTCTAGTGGAACACATGGGGGTCTC
  ATTGAAAAGCTCTCTGATGAGCACCTCCTTTTGTGCAAAGTTAATTTTTTCTCGACAATA
  AAGATATTCCGTGTCTTTACCCCTGAACTAAGACACAGGGAGTATTTCAGAGGCCAGCGT
  AGGAGTCATTGACAACRAAAAGCCGAGAACCCAGGGCCAGCAGTGGAGCCTCAGCAGACC
  AGGGCCTGGTCCTTGCTAACTGCTGCAGGGTGGAGTTTGATCTGGCAGACCCGATCCTCC
  TTCATGAACACCCAGCAACCTGAGCAAGTCCCGGCCCTGCCCTCAGCGAGCCCGGCAGGC
  GTCCTGGGACAGCTCAGTGTTGGAGGGCCACCTGAACCACGAGCCAGGGCTGGGGCTTGC
  ATGTCATTGTCTATGACAGCGTCAAGACTGGCCCTTGGCACCGTGCTGTGTGGAAACCCT
  CCCCTCTGAGACTCCACTGAGACGTGGCTGAGTGAAATCTTCCTCGTCAGTGGTCAAGGT
  GTGTCATCCATACAGCTCCATGCCTTTGTCTTTTTTAAATGTAATTAAAAAAGGAACCAA
  CTGGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001077365
• ORF Size: 2178 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone is found to be a good match to NM_001077365.1 except for 2 SNPs.

Reference Data

• RefSeq: NM_001077365.1, NP_001070833.1
• RefSeq Size: 3080
• RefSeq ORF: 2178
• Locus ID: 10585
• Protein Families: Transmembrane
• Protein Pathways: O-Mannosyl glycan biosynthesis
• Gene Summary: The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 4 both encode isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.