RASA4 (NM_001079877) Human Untagged Clone

CAT#: SC315831

RASA4 (untagged)-Human RAS p21 protein activator 4 (RASA4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASA4
• Synonyms: CAPRI; GAPL
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001079877, the custom clone sequence may differ by one or more nucleotides
  ATGGCCAAGCGCAGCTCGCTGTACATCCGCATCGTGGAGGGGAAGAACCTTCCCGCCAAG
  GACATCACTGGCAGCAGCGACCCCTACTGCATCGTGAAGGTGGACAATGAGCCCATCATC
  AGGACAGCCACAGTGTGGAAGACCCTGTGCCCCTTCTGGGGTGAGGAGTACCAAGTGCAC
  CTGCCGCCCACCTTCCACGCTGTGGCTTTCTATGTCATGGATGAGGATGCCCTCAGCCGG
  GACGACGTTATCGGAAAGGTCTGCCTTACAAGGGACACCATAGCCTCTCACCCTAAGGGT
  TTCAGCGGGTGGGCCCACCTGACGGAGGTCGACCCCGATGAGGAGGTGCAGGGCGAGATC
  CACCTGCGGCTGGAAGTGTGGCCAGGGGCCCGGGCCTGCCGGCTACGCTGCTCTGTGCTG
  GAGGCCAGGGATCTGGCCCCAAAGGACCGCAATGGCACATCTGACCCCTTCGTCCGAGTG
  CGCTACAAGGGCCGGACACGGGAGACCTCGATCGTGAAGAAGTCATGCTACCCACGCTGG
  AATGAGACGTTTGAATTTGAGCTGCAGGAGGGGGCCATGGAGGCGCTGTGCGTGGAGGCC
  TGGGACTGGGACCTCGTCAGCCGAAACGACTTCCTGGGCAAAGTGGTGATTGATGTCCAG
  AGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAG
  AGCCGGCGGCATGACGAGGGCAACCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGAC
  GAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCACGAGGTC
  AAGCTGGGCATGCAGGGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACC
  GAGTGTCGCCAGGACGTGGCCACGAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCC
  AAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCAGTGAGACCAACACC
  CTGTTCCGGAGCAACTCTCTGGCCTCAAAGTCCATGGAGTCTTTTCTGAAGGTGGCCGGG
  ATGCAGTACCTGCACGGCGTCCTGGGCCCCATCATCAACAAGGTGTTTGAGGAGAAGAAG
  TACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGGGTGCTCCGGGCTGCAC
  CGCCCGCAGACCGAGGCCGAGGTGCTGGAGCAGAGCGCGCAGACGCTGCGCGCCCACCTG
  GGGGCCCTGCTGAGCGCGCTCAGCCGCTCGGTTCGCGCGTGCCCCGCCGTGGTGCGCGCC
  ACCTTCCGCCAGCTCTTCCGGCGCGTGCGCGAGCGCTTCCCCGGCGCCCAGCACGAGAAT
  GTACCGTTCATCGCCGTCACCAGCTTCCTGTGCCTGCGCTTCTTCTCTCCCGCCATCATG
  TCGCCCAAGCTCTTCCACCTGCGGGAGCGCCACGCGGACGCCCGCACCAGCCGCACCCTG
  CTCCTGTTGGCCAAGGCAGTCCAGAACGTGGGCAACATGGACACGCCGGCTTCCAGGGCC
  AAGGAGGCTTGGATGGAGCCGCTGCAGCCCACCGTGCGCCAGGGCGTGGCGCAGCTGAAG
  GACTTCATCACCAAGCTCGTGGACATCGAGGAGAAGGACGAGCTGGACCTGCAGCGGACG
  CTGAGTTTGCAGGCGCCACCTGTGAAGGAGGGGCCACTCTTCATCCACAGGACCAAGGGC
  AAGGGCCCCCTCATGTCCTCCTCCTTCAAGAAGCTCTACTTCTCCCTCACTACCGAGGCC
  CTCAGCTTCGCGAAGACGCCCAGCTCCAAGTGTGTGAATGAGCTTAACCAGTGGCTGTCT
  GCGCTGCGGAAGGTGAGCATCAACAACACCGGACTGCTGGGCTCCTACCACCCTGGCGTC
  TTCCGTGGGGACAAGTGGAGCTGCTGCCACCAAAAAGAGAAGACAGGTCAGGGCTGCGAT
  AAGACCCGGTCACGGGTGACCCTGCAGGAGTGGAATGACCCTCTTGACCATGACCTTGAG
  GCCCAGCTCATCTGCCGGCACCTGCTGGGCGTGGAGGCCATGCTGTGGGAGAGGCACCGG
  GAGCTGAGCGGGGGCGCAGAGGCAGGCACGGTGCCCACGAGCCCTGGCAAAGTCCCCGAG
  GACTCATTGGCCCGGCTGCTCCGGGTGCTGCAGGACCTCCGCGAGGCCCATAGCTCCAGC
  CCGGCCGGCTCCCCACCCTCAGAGCCCAACTGCCTCCTGGAGCTGCAGACG
  
• Restriction Sites: Please inquire
• ACCN: NM_001079877
• ORF Size: 2274 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001079877.1, NP_001073346.1
• RefSeq Size: 5488
• RefSeq ORF: 2274
• Locus ID: 10156
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.