RBFOX2 (NM_001082579) Human Untagged Clone

CAT#: SC315999

RBFOX2 (untagged)-Human RNA binding protein, fox-1 homolog (C. elegans) 2 (RBFOX2), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RBFOX2
• Synonyms: dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBM9; RTA
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001082579 edited
  CCGGCTCCCGGAGGCGAGGGGGGCGCGGGCGGATGGCGGAGGGCGCCCAGCCGCAGCAGC
  CGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGGGGCATGAAGCGGGAGTCGGAGCTGGAGC
  TGCCGGTGCCCGGAGCGGGAGGAGACGGAGCCGATCCCGGCCTGAGCAAGCGGCCGCGCA
  CTGAGGAGGCGGCGGCCGACGGTGGCGGCGGGATGCAGAACGAGCCTCTGACTCCAGGTT
  ATCATGGATTCCCAGCGCGGGACAGCCAGGGTAACCAGGAGCCGACAACAACTCCTGACG
  CAATGGTTCAGCCTTTTACTACCATCCCATTTCCACCACCTCCGCAGAATGGAATTCCCA
  CAGAGTATGGGGTGCCACACACTCAAGACTATGCCGGCCAGACCGGTGAGCATAACCTGA
  CACTCTACGGAAGTACGCAAGCCCACGGGGAGCAGAGCAGCAACTCACCCAGCACACAAA
  ATGGATCTCTTACGACAGAAGGTGGAGCACAGACAGACGGCCAGCAGTCACAGACACAAA
  GTAGTGAAAATTCAGAGAGTAAATCTACCCCGAAACGGCTGCATGTCTCTAATATTCCTT
  TCCGCTTCCGGGACCCTGACCTCCGGCAGATGTTTGGGCAGTTTGGCAAAATCCTAGATG
  TAGAAATAATCTTTAATGAACGTGGCTCTAAGGGATTCGGGTTCGTAACTTTCGAGAATA
  GTGCTGATGCAGACAGGGCCAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAA
  TCGAGGTGAATAATGCTACAGCACGTGTAATGACCAATAAGAAGATGGTCACACCATATG
  CAAATGGTTGGAAATTAAGCCCAGTAGTTGGAGCTGTATATGGTCCGGAGTTATATGCAG
  CATCCAGCTTTCAAGCAGATGTGTCCCTAGGCAATGATGCAGCAGTGCCCCTATCAGGAA
  GAGGGGGTATCAACACTTACATTCCTTTAATCAGTCTCCCTTTAGTTCCTGGCTTCCCTT
  ACCCTACTGCAGCCACCACGGCAGCCGCTTTCAGAGGAGCCCATTTGAGGGGCAGAGGGC
  GGACAGTATATGGTGCAGTCCGAGCGGTACCTCCAACAGCCATCCCCGCCTATCCAGGTG
  TGGTTTACCAGGACGGATTTTACGGTGCTGACCTCTATGGTGGATATGCAGCCTACAGAT
  ATGCACAGCCTGCTACTGCAACCGCAGCCACCGCTGCTGCAGCCGCTGCAGCCGCTTACA
  GTGACGGTTATGGCAGGGTGTACACAGCCGACCCCTACCATGCCCTTGCCCCTGCCGCTA
  GCTATGGAGTTGGCGCTGTGGCGAGTTTATACCGAGGTGGCTACAGCCGATTTGCCCCCT
  ACTGAAGTGACGTGAGACCCCTGCAAATGGGACAGCCCCCCAGTTCATGAGGCCTGGCTA
  TTGCAATATTTACTAGTAGAGGAACTCTATAGCAAGATGAAGAGGAAAAACAAACAAACA
  AACAAAAAAAAACACAAAAAAAGAAAGAATACTTTTTTATACCTCACTATGTTCTTTGAA
  TATGTATTTTTCCTTTAAATTTCTGCCTTTAATTCTTTTGTTCCAAAGATTGTGCATTTT
  TTTCTTTTTTTTTTTAAACTGTGGTAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001082579
• ORF Size: 1353 bp
• Insert Size: 1700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001082579.1, NP_001076048.1
• RefSeq Size: 6954
• RefSeq ORF: 1353
• Locus ID: 23543
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (6) contains a distinct 5' UTR and 5' CDS, compared to variant 1. The resulting protein (isoform 6) is longer and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.