PTOP (ACD) (NM_001082487) Human Untagged Clone

CAT#: SC316006

ACD (untagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACD
• Synonyms: PIP1; PTOP; TINT1; TPP1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001082487, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTGGCCGCTGTCAGAGTGACGCCGCGATGAGAGTAAACGGGCCAGCATCCCGTGCACCAGCGGGGT
  GGACCAGCGGGAGTCTGCACACAGGCCCCCGAGCAGGACGCCCTCGTGCGCAGGCGCGGGGTGTACGTGG
  GCGGGGCCTCCTCCTCCGGCCCCGCCCAGCGAAGGAGCTTCCTCTTCCGAGGAAAGGCGGGGCCTGGGCG
  CCCGCGGGAAACCCGGGCCCGTTGCATCCGCTGGGTGTAGCCGTGGGGATGGCAGGTTCGGGGAGGCTGG
  TCCTACGGCCCTGGATTCGGGAGCTGATTCTGGGGTCAGAGACACCCTCCAGTCCACGAGCCGGGCAGCT
  GCTTGAGGACGCCGAGGCCGCGGTCGCGGGCCCATCCCACGCCCCTGATACGTCCGACGTCGGGGCCACG
  CTGCTTGTGTCTGACGGGACCCACAGTGTCCGATGCCTGGTGACGCGGGAGGCCCTGGACACCTCGGACT
  GGGAGGAGAAGGAGTTCGGCTTCCGCGGGACAGAGGGCCGGCTGCTGCTGCTGCAGGACTGCGGGGTTCA
  TGTCCAGGTCGCTGAGGGCGGCGCGCCCGCAGAGTTCTATCTCCAGGTGGACCGCTTCAGCCTGCTGCCC
  ACGGAGCAGCCCCGGCTACGGGTGCCTGGTTGCAACCAAGACTTAGATGTTCAGAAAAAGCTCTATGACT
  GCCTTGAGGAGCACCTTTCAGAGTCCACCTCGTCCAATGCAGGCCTATCACTGTCCCAGCTTCTGGATGA
  AATGCGGGAGGACCAGGAGCATCAGGGGGCACTCGTGTGCCTGGCTGAAAGCTGCCTGACACTGGAGGGC
  CCTTGCACAGCACCCCCTGTCACCCACTGGGCTGCCTCACGATGCAAGGCCACGGGAGAAGCTGTGTACA
  CTGTCCCCAGCTCAATGCTGTGCATCTCTGAGAATGACCAGCTAATTCTGAGCTCTCTAGGCCCCTGTCA
  GAGGACACAGGGCCCTGAGCTGCCCCCACCAGACCCGGCTCTGCAGGACCTATCTCTGACCCTCATAGCC
  TCTCCTCCTTCCTCACCCAGTTCCTCAGGAACCCCGGCCTTACCCGGCCACATGTCATCCGAGGAAAGTG
  GTACCAGCATCAGCCTTCTGCCTGCCCTGTCCTTGGCTGCTCCAGACCCAGGGCAGAGAAGCAGCTCCCA
  GCCCTCACCAGCCATCTGCTCAGCCCCTGCCACCCTGACCCCCAGGTCCCCACACGCCAGCCGTACCCCC
  AGCTCCCCACTCCAGAGCTGCACTCCCAGTCTCTCACCCCGTAGCCATGTCCCCAGTCCACACCAGGCTC
  TTGTGACCAGGCCCCAGAAACCTAGCCTGGAGTTCAAGGAGTTTGTAGGGTTGCCCTGCAAGAATCGGCC
  GCCTTTTCCCAGGACCGGAGCTACCAGGGGAGCCCAGGAGCCCTGCTCTGTCTGGTATGAGTATGAGCCA
  CCCTGCACGTCCCTCTGTGCTCGGGTCCAAGCTGTCAGGCTTCCTCCCCAGCTCATGGCCTGGGCCTTGC
  ACTTTCTGATGGATGCACAGCCAGGGTCTGAGCCAACTCCGATGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001082487
• ORF Size: 1587 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001082487.1, NP_001075956.1
• RefSeq Size: 2047
• RefSeq ORF: 1587
• Locus ID: 65057
• Gene Summary: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) uses alternate in-frame splice sites in the 5' and 3' coding regions, compared to variant 1, resulting in a shorter protein (isoform 3).