SCN3A (NM_001081676) Human Untagged Clone

CAT#: SC316037

SCN3A (untagged)-Human sodium channel, voltage-gated, type III, alpha subunit (SCN3A), transcript variant 2


  "NM_001081676" in other vectors (3)

Reconstitution Protocol

USD 3,960.00

5 Days*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SCN3A
Synonyms EIEE62; FFEVF4; NAC3; Nav1.3
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001081676 edited
AGAGAGAAAAAAAATTGTAACTAATTTGTAAACCTCTGTGGTCAAAAAAAAAAAAAAAAA
AAAAAAGCTGAACAGCTGCAGAGGAAGACACGTTATACCCTAACCATCTTGGATGCTGGG
CTTTGTTATGCTGTAATTCATAAGGCTCTGTTTTATCAGAGATTATGGAGCAAGAAAACT
GAAGCCAAGCCACATCAAGGTTTGACAGGGATGAGATACCTGTCAAGGATTCATAGTAGA
GTGGCTTACTGGGAAAGGAGCAAAGAATCTCTTCTAGGGATATTGTAAGAATAAATGAGA
TAATTCACAGAAGGGACCTGGAGCTTTTCCGGAAAAAGGTGCTGTGACTATCTAAGGTAA
TTCGTATGCAAGAAGCTACACGTAATTAAATGTGCAGGATGAAAAGATGGCACAGGCACT
GTTGGTACCCCCAGGACCTGAAAGCTTCCGCCTTTTTACTAGAGAATCTCTTGCTGCTAT
CGAAAAACGTGCTGCAGAAGAGAAAGCCAAGAAGCCCAAAAAGGAACAAGATAATGATGA
TGAGAACAAACCAAAGCCAAATAGTGACTTGGAAGCTGGAAAGAACCTTCCATTTATTTA
TGGAGACATTCCTCCAGAGATGGTGTCAGAGCCCCTGGAGGACCTGGATCCCTACTATAT
CAATAAGAAAACTTTTATAGTAATGAATAAAGGAAAGGCAATTTTCCGATTCAGTGCCAC
CTCTGCCTTGTATATTTTAACTCCACTAAACCCTGTTAGGAAAATTGCTATCAAGATTTT
GGTACATTCTTTATTCAGCATGCTTATCATGTGCACTATTTTGACCAACTGTGTATTTAT
GACCTTGAGCAACCCTCCTGACTGGACAAAGAATGTAGAGTACACATTCACTGGAATCTA
TACCTTTGAGTCACTTATAAAAATCTTGGCAAGAGGGTTTTGCTTAGAAGATTTTACGTT
TCTTCGTGATCCATGGAACTGGCTGGATTTCAGTGTCATTGTGATGGCATATGTGACAGA
GTTTGTGGACCTGGGCAATGTCTCAGCGTTGAGAACATTCAGAGTTCTCCGAGCACTGAA
AACAATTTCAGTCATTCCAGGTTTAAAGACCATTGTGGGGGCCCTGATCCAGTCGGTAAA
GAAGCTTTCTGATGTGATGATCCTGACTGTGTTCTGTCTGAGCGTGTTTGCTCTCATTGG
GCTGCAGCTGTTCATGGGCAATCTGAGGAATAAATGTTTGCAGTGGCCCCCAAGCGATTC
TGCTTTTGAAACCAACACCACTTCCTACTTTAATGGCACAATGGATTCAAATGGGACATT
TGTTAATGTAACAATGAGCACATTTAACTGGAAGGATTACATTGGAGATGACAGTCACTT
TTATGTTTTGGATGGGCAAAAAGACCCTTTACTCTGTGGAAATGGCTCAGATGCAGGCCA
GTGTCCAGAAGGATACATCTGTGTGAAGGCTGGTCGAAACCCCAACTATGGCTACACAAG
CTTTGACACCTTTAGCTGGGCTTTCCTGTCTCTATTTCGACTCATGACTCAAGACTACTG
GGAAAATCTTTACCAGTTGACATTACGTGCTGCTGGGAAAACATACATGATATTTTTTGT
CCTGGTCATTTTCTTGGGCTCATTTTATTTGGTGAATTTGATCCTGGCTGTGGTGGCCAT
GGCCTATGAGGAGCAGAATCAGGCCACCTTGGAAGAAGCAGAACAAAAAGAGGCCGAATT
TCAGCAGATGCTCGAACAGCTTAAAAAGCAACAGGAAGAAGCTCAGGCAGTTGCGGCAGC
ATCAGCTGCTTCAAGAGATTTCAGTGGAATAGGTGGGTTAGGAGAGCTGTTGGAAAGTTC
TTCAGAAGCATCAAAGTTGAGTTCCAAAAGTGCTAAAGAATGGAGGAACCGAAGGAAGAA
AAGAAGACAGAGAGAGCACCTTGAAGGAAACAACAAAGGAGAGAGAGACAGCTTTCCCAA
ATCCGAATCTGAAGACAGCGTCAAAAGAAGCAGCTTCCTTTTCTCCATGGATGGAAACAG
ACTGACCAGTGACAAAAAATTCTGCTCCCCTCATCAGTCTCTCTTGAGTATCCGTGGCTC
CCTGTTTTCCCCAAGACGCAATAGCAAAACAAGCATTTTCAGTTTCAGAGGTCGGGCAAA
GGATGTTGGATCTGAAAATGACTTTGCTGATGATGAACACAGCACATTTGAAGACAGCGA
AAGCAGGAGAGACTCACTGTTTGTGCCGCACAGACATGGAGAGCGACGCAACAGTAACGG
CACCACCACAGAAACGGAAGTCAGAAAGAGAAGGTTAAGCTCTTACCAGATTTCAATGGA
GATGCTGGAGGATTCCTCTGGAAGGCAAAGAGCCGTGAGCATAGCCAGCATTCTGACCAA
CACAATGGAAGAACTTGAAGAATCTAGACAGAAATGTCCGCCATGCTGGTATAGATTTGC
CAATGTGTTCTTGATCTGGGACTGCTGTGATGCATGGTTAAAAGTAAAACATCTTGTGAA
TTTAATTGTTATGGATCCATTTGTTGATCTTGCCATCACTATTTGCATTGTCTTAAATAC
CCTCTTTATGGCCATGGAGCACTACCCCATGACTGAGCAATTCAGTAGTGTGTTGACTGT
AGGAAACCTGGTCTTTACTGGGATTTTCACAGCAGAAATGGTTCTCAAGATCATTGCCAT
GGATCCTTATTACTATTTCCAAGAAGGCTGGAATATCTTTGATGGAATTATTGTCAGCCT
CAGTTTAATGGAGCTTGGTCTGTCAAATGTGGAGGGATTGTCTGTACTGCGATCATTCAG
ACTGCTTAGAGTTTTCAAGTTGGCAAAATCCTGGCCCACACTAAATATGCTAATTAAGAT
CATTGGCAATTCTGTGGGGGCTCTAGGAAACCTCACCTTGGTGTTGGCCATCATCGTCTT
CATTTTTGCTGTGGTCGGCATGCAGCTCTTTGGTAAGAGCTACAAAGAATGTGTCTGCAA
GATCAATGATGACTGTACGCTCCCACGGTGGCACATGAACGACTTCTTCCACTCCTTCCT
GATTGTGTTCCGCGTGCTGTGTGGAGAGTGGATAGAGACCATGTGGGACTGTATGGAGGT
CGCTGGCCAAACCATGTGCCTTATTGTTTTCATGTTGGTCATGGTCATTGGAAACCTTGT
GGTTCTGAACCTCTTTCTGGCCTTATTGTTGAGTTCATTTAGCTCAGACAACCTTGCTGC
TACTGATGATGACAATGAAATGAATAATCTGCAGATTGCAGTAGGAAGAATGCAAAAGGG
AATTGATTATGTGAAAAATAAGATGCGGGAGTGTTTCCAAAAAGCCTTTTTTAGAAAGCC
AAAAGTTATAGAAATCCATGAAGGCAATAAGATAGACAGCTGCATGTCCAATAATACTGG
AATTGAAATAAGCAAAGAGCTTAATTATCTTAGAGATGGGAATGGAACCACCAGTGGTGT
AGGTACTGGAAGCAGTGTTGAAAAATACGTAATCGATGAAAATGATTATATGTCATTCAT
AAACAACCCCAGCCTCACCGTCACAGTGCCAATTGCTGTTGGAGAGTCTGACTTTGAAAA
CTTAAATACTGAAGAGTTCAGCAGTGAGTCAGAACTAGAAGAAAGCAAAGAGAAATTAAA
TGCAACCAGCTCATCTGAAGGAAGCACAGTTGATGTTGTTCTACCCCGAGAAGGTGAACA
AGCTGAAACTGAACCCGAAGAAGACCTTAAACCGGAAGCTTGTTTTACTGAAGGATGTAT
TAAAAAGTTTCCATTCTGTCAAGTAAGTACAGAAGAAGGCAAAGGGAAGATCTGGTGGAA
TCTTCGAAAAACCTGCTACAGTATTGTTGAGCACAACTGGTTTGAGACTTTCATTGTGTT
CATGATCCTTCTCAGTAGTGGTGCATTGGCCTTTGAAGATATATACATTGAACAGCGAAA
GACTATCAAAACCATGCTAGAATATGCTGACAAAGTCTTTACCTATATATTCATTCTGGA
AATGCTTCTCAAATGGGTTGCTTATGGATTTCAAACATATTTCACTAATGCCTGGTGCTG
GCTAGATTTCTTGATCGTTGATGTTTCTTTGGTTAGCCTGGTAGCCAATGCTCTTGGCTA
CTCAGAACTCGGTGCCATCAAATCATTACGGACATTAAGAGCTTTAAGACCTCTAAGAGC
CTTATCCCGGTTTGAAGGCATGAGGGTGGTTGTGAATGCTCTTGTTGGAGCAATTCCCTC
TATCATGAATGTGCTGTTGGTCTGTCTCATCTTCTGGTTGATCTTTAGCATCATGGGTGT
GAATTTGTTTGCTGGCAAGTTCTACCACTGTGTTAACATGACAACGGGTAACATGTTTGA
CATTAGTGATGTTAACAATTTGAGTGACTGTCAGGCTCTTGGCAAGCAAGCTCGGTGGAA
AAACGTGAAAGTAAACTTTGATAATGTTGGCGCTGGCTATCTTGCACTGCTTCAAGTGGC
CACATTTAAAGGCTGGATGGATATTATGTATGCAGCTGTTGATTCACGAGATGTTAAACT
TCAGCCTGTATATGAAGAAAATCTGTACATGTATTTATACTTTGTCATCTTTATCATCTT
TGGGTCATTCTTCACTCTGAATCTATTCATTGGTGTCATCATAGATAACTTCAACCAGCA
GAAAAAGAAGTTTGGAGGTCAAGACATCTTTATGACAGAGGAACAGAAAAAATATTACAA
TGCAATGAAGAAACTTGGATCCAAGAAACCTCAGAAACCCATACCTCGCCCAGCAAACAA
ATTCCAAGGAATGGTCTTTGATTTTGTAACCAGACAAGTCTTTGATATCAGCATCATGAT
CCTCATCTGCCTCAACATGGTCACCATGATGGTGGAAACGGATGACCAGGGCAAATACAT
GACCCTAGTTTTGTCCCGGATCAACCTAGTGTTCATTGTTCTGTTCACTGGAGAATTTGT
GCTGAAGCTCGTCTCCCTCAGACACTACTACTTCACTATAGGCTGGAACATCTTTGACTT
TGTGGTGGTGATTCTCTCCATTGTAGGTATGTTTCTGGCTGAGATGATAGAAAAGTATTT
TGTGTCCCCTACCTTGTTCCGAGTGATCCGTCTTGCCAGGATTGGCCGAATCCTACGTCT
GATCAAAGGAGCAAAGGGGATCCGCACGCTGCTCTTTGCTTTGATGATGTCCCTTCCTGC
GTTGTTTAACATCGGCCTCCTGCTCTTCCTGGTCATGTTTATCTATGCCATCTTTGGGAT
GTCCAACTTTGCCTATGTTAAAAAGGAAGCTGGAATTGATGACATGTTCAACTTTGAGAC
CTTTGGCAACAGCATGATCTGCTTGTTCCAAATTACAACCTCTGCTGGCTGGGATGGATT
GCTAGCACCTATTCTTAATAGTGCACCACCCGACTGTGACCCTGACACAATTCACCCTGG
CAGCTCAGTTAAGGGAGACTGTGGGAACCCATCTGTTGGGATTTTCTTTTTTGTCAGTTA
CATCATCATATCCTTCCTGGTTGTGGTGAACATGTACATCGCGGTCATCCTGGAGAACTT
CAGTGTTGCTACTGAAGAAAGTGCAGAGCCCCTGAGTGAGGATGACTTTGAGATGTTCTA
TGAGGTTTGGGAAAAGTTTGATCCCGATGCGACCCAGTTTATAGAGTTCTCTAAACTCTC
TGATTTTGCAGCTGCCCTGGATCCTCCTCTTCTCATAGCAAAACCCAACAAAGTCCAGCT
TATTGCCATGGATCTGCCCATGGTCAGTGGTGACCGGATCCACTGTCTTGATATTTTATT
TGCCTTTACAAAGCGTGTTTTGGGTGAGAGTGGAGAGATGGATGCCCTTCGAATACAGAT
GGAAGACAGGTTTATGGCATCAAACCCCTCCAAAGTCTCTTATGAGCCTATTACAACCAC
TTTGAAACGTAAACAAGAGGAGGTGTCTGCCGCTATCATTCAGCGTAATTTCAGATGTTA
TCTTTTAAAGCAAAGGTTAAAAAATATATCAAGTAACTATAACAAAGAGGCAATTAAAGG
GAGGATTGACTTACCTATAAAACAAGACATGATTATTGACAAACTAAATGGGAACTCCAC
TCCAGAAAAAACAGATGGGAGTTCCTCTACCACCTCTCCTCCTTCCTATGATAGTGTAAC
AAAACCAGACAAGGAAAAGTTTGAGAAAGACAAACCAGAAAAAGAAAGCAAAGGAAAAGA
GGTCAGAGAAAATCAAAAGTAAAAAGAAACAAAGAATTATCTTTGTGATCAATTGTTTAC
AGCCTATGAAGGTAAAGTATATGTGTCAACTGGACTTCAAGAGGAGGTCCATGCCAAACT
GACTGTTTTAACAAATACTCATAGTCAGTGCCTATACAAGACAGTGAAGTGACCTCTCTG
TCACTGCAACTCTGTGAAGCAGGGTATCAACATTGACAAGAGGTTGCTGTTTTTATTACC
AGCTGACACTGCTGAGGAGAAACCCAATGGCTACCTAGACTATAGGGATAGTTGTGCAAA
GTGAACATTGTAACTACACCAAACACCTTTAGTACAGTCCTTGCATCCATTCTATTTTTA
ACTTCCATATCTGCCATATTTTTACAAAATTTGTTCTAGTGCATTTCCATGGTCCCCAAT
TCATAGTTTATTCATAATGCTATGTCACTATTTTTGTAAATGAGGTTTACGTTGAAGAAA
CAGTATACAAGAACCCTGTCTCTCAAATGATCAGACAAAGGTGTTTTGCCAGAGAGATAA
AATTTTTGCTCAAAACCAGAAAAAGAATTGTAATGGCTACAGTTTCAGTTACTTCCATTT
TCTAGATGGCTTTAATTTTGAAAGTATTTTAGTCTGTTATGTTTGTTTCTATCTGAACAG
TTATGTGCCTGTAAAGTCTCCTCTAATATTTAAAGGATTATTTTTATGCAAAGTATTCTG
TTTCAGCAAGTGCAAATTTTATTCTAAGTTTCAGAGCTCTATATTTAATTTAGGTCAAAT
GCTTTCCAAAAAGTAATCTAATAAATCCATTCTAGAAAAATATATCTAAAGTATTGCTTT
AGAATAGTTGTTCCACTTTCTGCTGCAGTATTGCTTTGCCATCTTCTGCTCTCAGCAAAG
CTGATAGTCTATGTCAATTAAATACCCTATGTTATGTAAATAGTTATTTTATCCTGTGGT
GCATGTTTGGGCAAATATATATATAGCCTGATAAACAACTTCTATTAAATCAAATATGTA
CCACAGTGTATGTGTCTTTTGCAAGCTTCCAACAGGGATGTATCCTGTATCATTCATTAA
ACATAGTTTAAAGGCTATCACTAATGCATGTTAATATTGCCTATGCTGCTCTATTTTACT
CAATCCATTCTTCACAAGTCTTGGTTAAAGAATGTCACATATTGGTGATAGAATGAATTC
AACCTGCTCTGTCCATTATGTCAAGCAGAATAATTTGAAGCTATTTACAAACACCTTTAC
TTTTGCACTTTTAATTCAACATGAGTATCATATGGTATCTCTCTAGATTTCAAGGAAACA
CACTGGATACTGCCTACTGACAAAACCTATTCTTCATATTTTGCTAAAAATATGTCTAAA
ACTTGTTTAAATATAAATAATGTAAAAATATAATCAACTTTATTTGTCAGCATTTTGTAC
ATAAGAAAATTATTTTCAGGTTGATGACATCACAATTTATTTTACTTTATGCTTTTGCTT
TTGATTTTTAATCACAATTCCAAACTTTTGAATCCATAAGATTTTTCAATGGATAATTTC
CTAAAATAAAAGTTAGATAATGGGTTTTATGGATTTCTTTGTTATAATATATTTTCTACC
ATTCCAATAGGAGATACATTGGTCAAACACTCAAACCTAGATCATTTTCTACCAACTATG
GTTGCCTCAATATAACCTTTTATTCATAGATGTTTTTTTTTATTCAACTTTTGTAGTATT
TACGTATGCAGACTAGTCTTATTTTTTTAATTCCTGCTGCACTAAAGCTATTACAAATAT
AACATGGACTTTGTTCTTTTTAGCCATGAACAAAGTGGCAAAGTTGTGCAATTACCTAAC
ATGATATAAATTTTTGTTTTTTGCACAAACCAAAAGTTTAATGTTAATTCTTTTTACAAA
ACTATTTACTGTAGTGTATTGAAGAACTGCATGCAGGGAATTGCTATTGCTAAAAAGAAT
GGTGAGCTACGTCATTATTGAGCCAAAAGAATAAATTTCATTTTTTATTGCATTTCACTT
ATTGGCCTCTGGGGTTTTTTGTTTTTGTTTTTTGCTGTTGGCAGTTTAAAATATATATAA
TTAATAAAACCTGTGCTTGATCTGACATTTGTATACATAAAAGTTTACATGAATTTTACA
ACAAACTAGTGCATGATTCACCAAGCAGTACTACAGAACAAAGGCAAATTAAAAGCAGCT
TTGTGAACTTTTATGTGTGCAAAGGATCAAGTTCACATGTTCCAACTTTCAGGTTTGATA
ATAATAGTAGTAACCACCTACAATAGCTTTCAATTTCAATTAACTCCCTTGGCTATAAGC
ATCTAAACTCATCTTCTTTCAATATAATTGATGCTATCTCCTAATTACTTGGTGGCTAAT
AAATGTTACATTCTTTGTTACTTAAATGCATTATATAAACTCCTATGTATACATAAGGTA
TTAATGATATAGTTATTGAGAATTTATATTAACTTTTTTTTCAAGAACCCTTGGATTTAT
GTGAGGTCAAAACCAAACTCTTATTCTCAGTGGAAAACTCCAGTTGTAATGCATATTTTT
AAAGACAATTTGGATCTAAATATGTATTTCATAATTCTCCCATAATAAATTATATAAGGT
GGCCAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001081676
Insert Size 8900 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. This clone may be unstable or toxic at high copy number in common E. coli strain. We recommend using a lower copy number E. coli strain, such as CopyCutter strain (http://www.epibio.com/item.asp?ID=435) for transformation and plasmid preparation. Please be aware that the DNA yield could be low. Additional aliquots of this clone can be ordered from OriGene.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001081676.1, NP_001075145.1
RefSeq Size 8994 bp
RefSeq ORF 5856 bp
Locus ID 6328
Cytogenetics 2q24.3
Protein Families Druggable Genome, Ion Channels: Sodium, Transmembrane
Gene Summary 'Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2), also known as 12v1, SCN3A-s, or the adult form, uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a shorter protein (isoform 2).

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