SLIT2 (NM_004787) Human Untagged Clone

CAT#: SC316293

SLIT2 (untagged)-Human slit homolog 2 (Drosophila) (SLIT2)


  "NM_004787" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SLIT2
Synonyms SLIL3; Slit-2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_004787 edited
CAGACACTGCGCGGTTCCCTCGGAGCAGCAAGCTAAAGAAAGCCCCCAGTGCCGGCGAGG
AAGGAGGCGGCGGGGAAAGATGCGCGGCGTTGGCTGGCAGATGCTGTCCCTGTCGCTGGG
GTTAGTGCTGGCGATCCTGAACAAGGTGGCACCGCAGGCGTGCCCGGCGCAGTGCTCTTG
CTCGGGCAGCACAGTGGACTGTCACGGGCTGGCGCTGCGCAGCGTGCCCAGGAATATCCC
CCGCAACACCGAGAGACTGGATTTAAATGGAAATAACATCACAAGAATTACGAAGACAGA
TTTTGCTGGTCTTAGACATCTAAGAGTTCTTCAGCTTATGGAGAATAAGATTAGCACCAT
TGAAAGAGGAGCATTCCAGGATCTTAAAGAACTAGAGAGACTGCGTTTAAACAGAAATCA
CCTTCAGCTGTTTCCTGAGTTGCTGTTTCTTGGGACTGCGAAGCTATACAGGCTTGATCT
CAGTGAAAACCAAATTCAGGCAATCCCAAGGAAAGCTTTCCGTGGGGCAGTTGACATAAA
AAATTTGCAACTGGATTACAACCAGATCAGCTGTATTGAAGATGGGGCATTCAGGGCTCT
CCGGGACCTGGAAGTGCTCACTCTCAACAATAACAACATTACTAGACTTTCTGTGGCAAG
TTTCAACCATATGCCTAAACTTAGGACTTTTCGACTGCATTCAAACAACCTGTATTGTGA
CTGCCACCTGGCCTGGCTCTCCGACTGGCTTCGCCAAAGGCCTCGGGTTGGTCTGTACAC
TCAGTGTATGGGCCCCTCCCACCTGAGAGGCCATAATGTAGCCGAGGTTCAAAAACGAGA
ATTTGTCTGCAGTGTGGGTCACCAGTCATTTATGGCTCCTTCTTGTAGTGTTTTGCACTG
CCCTGCCGCCTGTACCTGTAGCAACAATATCGTAGACTGTCGTGGGAAAGGTCTCACTGA
GATCCCCACAAATCTTCCAGAGACCATCACAGAAATACGTTTGGAACAGAACACAATCAA
AGTCATCCCTCCTGGAGCTTTCTCACCATATAAAAAGCTTAGACGAATTGACCTGAGCAA
TAATCAGATCTCTGAACTTGCACCAGATGCTTTCCAAGGACTACGCTCTCTGAATTCACT
TGTCCTCTATGGAAATAAAATCACAGAACTCCCCAAAAGTTTATTTGAAGGACTGTTTTC
CTTACAGCTCCTATTATTGAATGCCAACAAGATAAACTGCCTTCGGGTAGATGCTTTTCA
GGATCTCCACAACTTGAACCTTCTCTCCCTATATGACAACAAGCTTCAGACCATCGCCAA
GGGGACCTTTTCACCTCTTCGGGCCATTCAAACTATGCATTTGGCCCAGAACCCCTTTAT
TTGTGACTGCCATCTCAAGTGGCTAGCGGATTATCTCCATACCAACCCGATTGAGACCAG
TGGTGCCCGTTGCACCAGCCCCCGCCGCCTGGCAAACAAAAGAATTGGACAGATCAAAAG
CAAGAAATTCCGTTGTTCAGCTAAAGAACAGTATTTCATTCCAGGTACAGAAGATTATCG
ATCAAAATTAAGTGGAGACTGCTTTGCGGATCTGGCTTGCCCTGAAAAGTGTCGCTGTGA
AGGAACCACAGTAGATTGCTCTAATCAAAAGCTCAACAAAATCCCGGAGCACATTCCCCA
GTACACTGCAGAGTTGCGTCTCAATAATAATGAATTTACCGTGTTGGAAGCCACAGGAAT
CTTTAAGAAACTTCCTCAATTACGTAAAATAAACTTTAGCAACAATAAGATCACAGATAT
TGAGGAGGGAGCATTTGAAGGAGCATCTGGTGTAAATGAAATACTTCTTACGAGTAATCG
TTTGGAAAATGTGCAGCATAAGATGTTCAAGGGATTGGAAAGCCTCAAAACTTTGATGTT
GAGAAGCAATCGAATAACCTGTGTGGGGAATGACAGTTTCATAGGACTCAGTTCTGTGCG
TTTGCTTTCTTTGTATGATAATCAAATTACTACAGTTGCACCAGGGGCATTTGATACTCT
CCATTCTTTATCTACTCTAAACCTCTTGGCCAATCCTTTTAACTGTAACTGCTACCTGGC
TTGGTTGGGAGAGTGGCTGAGAAAGAAGAGAATTGTCACGGGAAATCCTAGATGTCAAAA
ACCATACTTCCTGAAAGAAATACCCATCCAGGATGTGGCCATTCAGGACTTCACTTGTGA
TGACGGAAATGATGACAATAGTTGCTCCCCACTTTCTCGCTGTCCTACTGAATGTACTTG
CTTGGATACAGTCGTCCGATGTAGCAACAAGGGTTTGAAGGTCTTGCCGAAAGGTATTCC
AAGAGATGTCACAGAGTTGTATCTGGATGGAAACCAATTTACACTGGTTCCCAAGGAACT
CTCCAACTACAAACATTTAACACTTATAGACTTAAGTAACAACAGAATAAGCACGCTTTC
TAATCAGAGCTTCAGCAACATGACCCAGCTCCTCACCTTAATTCTTAGTTACAACCGTCT
GAGATGTATTCCTCCTCGCACCTTTGATGGATTAAAGTCTCTTCGATTACTTTCTCTACA
TGGAAATGACATTTCTGTTGTGCCTGAAGGTGCTTTCAATGATCTTTCTGCATTATCACA
TCTAGCAATTGGAGCCAACCCTCTTTACTGTGATTGTAACATGCAGTGGTTATCCGACTG
GGTGAAGTCGGAATATAAGGAGCCTGGAATTGCTCGTTGTGCTGGTCCTGGAGAAATGGC
AGATAAACTTTTACTCACAACTCCCTCCAAAAAATTTACCTGTCAAGGTCCTGTGGATGT
CAATATTCTAGCTAAGTGTAACCCCTGCCTATCAAATCCGTGTAAAAATGATGGCACATG
TAATAGTGATCCAGTTGACTTTTACCGATGCACCTGTCCATATGGTTTCAAGGGGCAGGA
CTGTGATGTCCCAATTCATGCCTGCATCAGTAACCCATGTAAACATGGAGGAACTTGCCA
CTTAAAGGAAGGAGAAGAAGATGGATTCTGGTGTATTTGTGCTGATGGATTTGAAGGAGA
AAATTGTGAAGTCAACGTTGATGATTGTGAAGATAATGACTGTGAAAATAATTCTACATG
TGTCGATGGCATTAATAACTACACATGCCTTTGCCCACCTGAGTATACAGGTGAGTTGTG
TGAGGAGAAGCTGGACTTCTGTGCCCAGGACCTGAACCCCTGCCAGCACGATTCAAAGTG
CATCCTAACTCCAAAGGGATTCAAATGTGACTGCACACCAGGGTACGTAGGTGAACACTG
CGACATCGATTTTGACGACTGCCAAGACAACAAGTGTAAAAACGGAGCCCACTGCACAGA
TGCAGTGAACGGCTATACGTGCATATGCCCCGAAGGTTACAGTGGCTTGTTCTGTGAGTT
TTCTCCACCCATGGTCCTCCCTCGTACCAGCCCCTGTGATAATTTTGATTGTCAGAATGG
AGCTCAGTGTATCGTCAGAATAAATGAGCCAATATGTCAGTGTTTGCCTGGCTATCAGGG
AGAAAAGTGTGAAAAATTGGTTAGTGTGAATTTTATAAACAAAGAGTCTTATCTTCAGAT
TCCTTCAGCCAAGGTTCGGCCTCAGACGAACATAACACTTCAGATTGCCACAGATGAAGA
CAGCGGAATCCTCCTGTATAAGGGTGACAAAGACCATATCGCGGTAGAACTCTATCGGGG
GCGTGTTCGTGCCAGCTATGACACCGGCTCTCATCCAGCTTCTGCCATTTACAGTGTGGA
GACAATCAATGATGGAAACTTCCACATTGTGGAACTACTTGCCTTGGATCAGAGTCTCTC
TTTGTCCGTGGATGGTGGGAACCCCAAAATCATCACTAACTTGTCAAAGCAGTCCACTCT
GAATTTTGACTCTCCACTCTATGTAGGAGGCATGCCAGGGAAGAGTAACGTGGCATCTCT
GCGCCAGGCCCCTGGGCAGAACGGAACCAGCTTCCACGGCTGCATCCGGAACCTTTACAT
CAACAGTGAGCTGCAGGACTTCCAGAAGGTGCCGATGCAAACAGGCATTTTGCCTGGCTG
TGAGCCATGCCACAAGAAGGTGTGTGCCCATGGCACATGCCAGCCCAGCAGCCAGGCAGG
CTTCACCTGCGAGTGCCAGGAAGGATGGATGGGGCCCCTCTGTGACCAACGGACCAATGA
CCCTTGCCTTGGAAATAAATGCGTACATGGCACCTGCTTGCCCATCAATGCGTTCTCCTA
CAGCTGTAAGTGCTTGGAGGGCCATGGAGGTGTCCTCTGTGATGAAGAGGAGGATCTGTT
TAACCCATGCCAGGCGATCAAGTGCAAGCAYGGGAAGTGCAGGCTTTCAGGTCTGGGGCA
GCCCTACTGTGAATGCAGCAGTGGATACACGGGGGACAGCTGTGATCGAGAAATCTCTTG
TCGAGGGGAAAGGATAAGAGATTATTACCAAAAGCAGCAGGGCTATGCTGCTTGCCAAAC
AACCAAGAAGGTGTCCCGATTAGAGTGCAGAGGTGGGTGTGCAGGAGGGCAGTGCTGTGG
ACCGCTGAGGAGCAAGCGGCGGAAATACTCTTTCGAATGCACTGACGGCTCCTCCTTTGT
GGACGAGGTTGAGAAAGTGGTGAAGTGCGGCTGTACGAGGTGTGTGTCCTAAACACACTC
CCGGCAGCTCTGTCTTT
>OriGene 5' read for NM_004787 unedited
GTACCCTCTGTATACGACTCCTATAGGGCGGCCGCCAGTGTGATGGATATCTGCAGAATT
CGCCCTTCAGACACTGCGCGGTTCCCTCGGAGCAGCAAGCTAAAGAAAGCCCCCAGTGCC
GGCGAGGAAGGAGGCGGCGGGGAAAGATGCGCGGCGTTGGCTGGCAGATGCTGTCCCTGT
CGCTGGGGTTAGTGCTGGCGATCCTGAACAAGGTGGCACCGCAGGCGTGCCCGGCGCAGT
GCTCTTGCTCGGGCAGCACAGTGGACTGTCACGGGCTGGCGCTGCGCAGCGTGCCCAGGA
ATATCCCCCGCAACACCGAGAGACTGGATTTAAATGGAAATAACATCACAAGAATTACGA
AGACAGATTTTGCTGGTCTTAGACATCTAAGAGTTCTTCAGCTTATGGAGAATAAGATTA
GCACCATTGAAAGAGGAGCATTCCAGGATCTTAAAGAACTAGAGAGACTGCGTTTAAACA
GAAATCACCTTCAGCTGTTTCCTGAGTTGCTGTTTCTTGGGACTGCGAAGCTATACAGGC
TTGATCTCAGTGAAAACCAAATTCAGGCAATCCCAAGGAAAGCTTTCCGTGGGGCAGTTG
ACATAAAAAATTTGCAACTGGATTACAACCAGATCAGCTGTATTGAAGATGGGGCATTCA
GGGCTCTCCGGGACCTGGAAGTGCTCACTCTCAACAATAACAACATTACTAGACTTTCTG
TGGCAAGTTTCAACCATATGCCTAAACTTAGACTTTTCGACTGCATTCAAACAACCTGTA
TTGTGACTGCCACCTGGCCCTGCTCTCCGACTGGCTTCGCCAAAGGCCTCGGGTTGGTCT
GTACACTCAGTGTATGGGCCCCTCCCACCTGAGAGCCATAATGTAGCCGAGTTCAAAAAC
GAGAATTTGTTCTGCAGTGGTCACCAGTCATTTATGGCT
Restriction Sites Please inquire     
ACCN NM_004787
ORF Size 4590 bp
Insert Size 4700
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_004787.1.
Reference Data
RefSeq NM_004787.1, NP_004778.1
RefSeq Size 4950
RefSeq ORF 4590
Locus ID 9353
Domains LRRNT, LRRCT, LRR, LamG, EGF_CA, LRR_TYP, CT, EGF, EGF, LRR_PS
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Axon guidance
Gene Summary This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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