CD20 (MS4A1) (NM_021950) Human Untagged Clone

CAT#: SC316358

MS4A1 (untagged)-Human membrane-spanning 4-domains, subfamily A, member 1 (MS4A1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MS4A1
• Synonyms: B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_021950 edited
  GAATTCGGCACGAGGACAAACTGCACCCACTGAACTCCGCAGCTAGCATCCAAATCAGCC
  CTTGAGATTTGAGGCCTTGGAGACTCAGGAGTTTTGAGAGCAAAATGACAACACCCAGAA
  ATTCAGTAAATGGGACTTTCCCGGCAGAGCCAATGAAAGGCCCTATTGCTATGCAATCTG
  GTCCAAAACCACTCTTCAGGAGGATGTCTTCACTGGTGGGCCCCACGCAAAGCTTCTTCA
  TGAGGGAATCTAAGACTTTGGGGGCTGTCCAGATTATGAATGGGCTCTTCCACATTGCCC
  TGGGGGGTCTTCTGATGATCCCAGCAGGGATCTATGCACCCATCTGTGTGACTGTGTGGT
  ACCCTCTCTGGGGAGGCATTATGTATATTATTTCCGGATCACTCCTGGCAGCAACGGAGA
  AAAACTCCAGGAAGTGTTTGGTCAAAGGAAAAATGATAATGAATTCATTGAGCCTCTTTG
  CTGCCATTTCTGGAATGATTCTTTCAATCATGGACATACTTAATATTAAAATTTCCCATT
  TTTTAAAAATGGAGAGTCTGAATTTTATTAGAGCTCACACACCATATATTAACATATACA
  ACTGTGAACCAGCTAATCCCTCTGAGAAAAACTCCCCATCTACCCAATACTGTTACAGCA
  TACAATCTCTGTTCTTGGGCATTTTGTCAGTGATGCTGATCTTTGCCTTCTTCCAGGAAC
  TTGTAATAGCTGGCATCGTTGAGAATGAATGGAAAAGAACGTGCTCCAGACCCAAATCTA
  ACATAGTTCTCCTGTCAGCAGAAGAAAAAAAAGAACAGACTATTGAAATAAAAGAAGAAG
  TGGTTGGGCTAACTGAAACATCTTCCCAACCAAAGAATGAAGAAGACATTGAAATTATTC
  CAATCCAAGAAGAGGAAGAAGAAGAAACAGAGACGAACTTTCCAGAACCTCCCCAAGATC
  AGGAATCCTCACCAATAGAAAATGACAGCTCTCCTTAAGTGATTTCTTCTGTTTTCTGTT
  TCCTTTTTTAAACATTAGTGTTCATAGCT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021950 unedited
  GAATTTGTATACGACTCACTATAGGCGGCNCGCGAATTCGCACGAGGACAAACTGCACCC
  ACTGAACTCCGCAGCTAGCATCCAAATCAGCCCTTGAGATTTGAGGCCTTGGAGACTCAG
  GAGTTTTGAGAGCAAAATGACAACACCCAGAAATTCAGTAAATGGGACTTTCCCGGCAGA
  GCCAATGAAAGGCCCTATTGCTATGCAATCTGGTCCAAAACCACTCTTCAGGAGGATGTC
  TTCACTGGTGGGCCCCACGCAAAGCTTCTTCATGAGGGAATCTAAGACTTTGGGGGCTGT
  CCAGATTATGAATGGGCTCTTCCACATTGCCCTGGGGGGTCTTCTGATGATCCCAGCAGG
  GATCTATGCACCCATCTGTGTGACTGTGTGGTACCCTCTCTGGGGAGGCATTATGTATAT
  TATTTCCGGATCACTCCTGGCAGCAACGGAGAAAAACTCCAGGAAGTGTTTGGTCAAAGG
  AAAAATGATAATGAATTCATTGAGCCTCTTTGCTGCCATTTCTGGAATGATTCTTTCAAT
  CATGGACATACTTAATATTAAAATTTCCCATTTTTTAAAAATGGAGAGTCTGAATTTTAT
  TAGAGCTCACACACCATATATTAACATATACAACTGTGAACCAGCTAATCCCTCTGAGAA
  AAACTCCCCATCTACCCAATACTGTTACAGCATACATTCTCTGTTCTTGCGCATCTTGTC
  AGTGATGCTGATCTTTGCCCTTCTTCCAGAACTTGTAATAGCTGGCATCGTTGAGAATGA
  ATGGAAAAGACCGTGCTCCAAACCAAATCTACATAGTTCTTCTGTCAACAGAAGAAAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021950 unedited
  TACCGCGGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTCTGTTGCAGAAAAGA
  CACAAAGATAGTTTTATTAATTTAGAACAAATTTTGAGAACTTTACATAGACAGAAATCT
  TCTATCTCCTTTTTTTCTAATTTTGGGGAATGTCTTCCACTAGTGGTCGCTAAAAATGTA
  GAAATATCATAGGGAGTGCAAATTACATTGTCTCTTTACCTGCCACAATCTGGCAGCACT
  CATCATGTAGCAAATGCCCAAATAATAGACTACAGATTATAGTGACTTCACCCTAGGTTA
  ACATTATTTCTAGGTAAGGTACTAGTATATCTGAATTGAAAAGTGGGGCAGCTGTTGACT
  CAGATTCGGCATTTTAATTACATTGTTTCCAAGTATGATATTCTGAGAGTGTCTATAGCA
  CTTAGTGTCTGCTTCATATAAACTACCAGTTATTATATATTTATGATGCAAGTAGTTTTC
  CAAATGTGGTGAAAGTCTGAGTCTTTTTATCCCCATGGGTAAAATCTGAATCTGGCTCTC
  TGTGTCTCTCAGTGCTTGTTTATTGCTGGTCAGAGAGTAAATTCTTGATAAAAGCTGTTG
  ACTTGGCTCTCACAGTTTATGCAGACATTGGAGAGACAATTTGGTTATTTCAAACATCAC
  AGGATTTGAGTAAGAAGACCTGGTTATGAAACAAGGCTCTCATAATTACTAGTTATGACT
  GTTGACAGTTACCCTTTTCTTGTTACAAGTATTTGCCCTCTTTGATTACTTGTAAATAGA
  GAAGGGATTCTTTTTGATCATGGACATCAATGAATTATTTGATGAATACTTTGCCATCTG
  GAAATATACTATAACTCAATGTAATATTATTTGAAATTGGGCACTCATGTGGCATTTCTA
  TGCCATTTTTTCTTTTTCGCTATGGCTAAAGTAGTAGACTGCAACATACCTAAAGGGGAG
  TAGGAAAGTAAGCCAACCTGTCATGTTACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021950
• Insert Size: 2740 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021950.3, NP_068769.2
• RefSeq Size: 3331 bp
• RefSeq ORF: 894 bp
• Locus ID: 931
• Cytogenetics: 11q12.2
• Domains: CD20
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage
• Gene Summary: 'This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (3) lacks a portion of the 5' UTR, compared to variant 1, but encodes the same protein.