IRF5 (NM_001098628) Human Untagged Clone

CAT#: SC316388

IRF5 (untagged)-Human interferon regulatory factor 5 (IRF5), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRF5
• Synonyms: interferon regulatory factor 5; SLEB10
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001098628 edited
  GGTGCTCCCTGGCGCAGCCACGCAGGCGCACCGCAGACAGACCCCTCTGCCATGAACCAG
  TCCATCCCAGTGGCTCCCACCCCACCCCGCCGCGTGCGGCTGAAGCCCTGGCTGGTGGCC
  CAGGTGAACAGCTGCCAGTACCCAGGGCTTCAATGGGTCAACGGGGAAAAGAAATTATTC
  TGCATCCCCTGGAGGCATGCCACAAGGCATGGTCCCAGCCAGGACGGAGATAACACCATC
  TTCAAGGCCTGGGCCAAGGAGACAGGGAAATACACCGAAGGCGTGGATGAAGCCGATCCG
  GCCAAGTGGAAGGCCAACCTGCGCTGTGCCCTTAACAAGAGCCGGGACTTCCGCCTCATC
  TACGACGGGCCCCGGGACATGCCACCTCAGCCCTACAAGATCTACGAGGTCTGCTCCAAT
  GGCCCTGCTCCCACAGACTCCCAGCCCCCTGAGGATTACTCTTTTGGTGCAGGAGAGGAG
  GAGGAAGAAGAGGAAGAGCTGCAGAGGATGTTGCCAAGCCTGAGCCTCACAGAGGATGTC
  AAGTGGCCGCCTACTCTGCAGCCGCCCACTCTGCAGCCGCCCGTGGTGCTGGGTCCCCCT
  GCTCCAGACCCCAGCCCCCTGGCTCCTCCCCCTGGCAACCCTGCTGGCTTCAGGGAGCTT
  CTCTCTGAGGTCCTGGAGCCTGGGCCCCTGCCTGCCAGCCTGCCCCCTGCAGGCGAACAG
  CTCCTGCCAGACCTGCTGATCAGCCCCCACATGCTGCCTCTGACCGACCTGGAGATCAAG
  TTTCAGTACCGGGGGCGGCCACCCCGGGCCCTCACCATCAGCAACCCCCATGGCTGCCGG
  CTCTTCTACAGCCAGCTGGAGGCCACCCAGGAGCAGGTGGAACTCTTCGGCCCCATAAGC
  CTGGAGCAAGTGCGCTTCCCCAGCCCTGAGGACATCCCCAGTGACAAGCAGCGCTTCTAC
  ACGAACCAGCTGCTGGATGTCCTGGACCGCGGGCTCATCCTCCAGCTACAGGGCCAGGAC
  CTTTATGCCATCCGCCTGTGTCAGTGCAAGGTGTTCTGGAGCGGGCCTTGTGCCTCAGCC
  CATGACTCATGCCCCAACCCCATCCAGCGGGAGGTCAAGACCAAGCTTTTCAGCCTGGAG
  CATTTTCTCAATGAGCTCATCCTGTTCCAAAAGGGCCAGACCAACACCCCACCACCCTTC
  GAGATCTTCTTCTGCTTTGGGGAAGAATGGCCTGACCGCAAACCCCGAGAGAAGAAGCTC
  ATTACTGTACAGGTGGTGCCTGTAGCAGCTCGACTGCTGCTGGAGATGTTCTCAGGGGAG
  CTATCTTGGTCAGCTGATAGTATCCGGCTACAGATCTCAAACCCAGACCTCAAAGACCGC
  ATGGTGGAGCAATTCAAGGAGCTCCATCACATCTGGCAGTCCCAGCAGCGGTTGCAGCCT
  GTGGCCCAGGCCCCTCCTGGAGCAGGCCTTGGTGTTGGCCAGGGGCCCTGGCCTATGCAC
  CCAGCTGGCATGCAATAACAAGGCTGCAGACGGTGACTGGCCCTGGCTTCCTGGGTGGCG
  GTGCGGACTGATGTGGAGATGTGACAGCCCCGATGAGCACCTGGCTGGCTGCAGGGTCCT
  ACCTCTGGGTTTCCTGGAAGTGGATTTGGGCCAAGAAGGAGAGGGAGAAAGGCCCGAGCC
  CCTGCCTTCCCGGGCCTTTCTCTCCTGGGCTGTCTCTGGTCTGGTCAGCCTGGCTCTCGG
  GAAATTCAGCCATGAGCAGGGAAAGAACTCTCCCAACCCTGGGGCCTAGCTGTATAGGAG
  GAATTGCCTAAGGGTGGCCCACTCTTGTGATTGCCCCATTTCCTCTGGCAACAAAAGCCA
  GAGTGTTGTGGGCCAAGTCCCCCCACAGGGCCTCTGCAGGGCATGGCCCTGATTTCCCTG
  GTTTGAGACTCACTTCCTCATCTCCCTGTCCTCTGAGATAATATGAGTGAGCACTTAGGT
  ATCATATCAGATGCTCAAGGCTGGCAGCTACCCCCTTCTTGAGAGTCCAAGAACCTGGAG
  CAGAAATAATTTTTATGTATTTTTGGATTAATGAATGTTAAAAACAGACTCAGCTGTTTC
  TTTCCTTTTACTACTACCAGTTGCTCCCATGCTGCTCCACCAGGCCCTGTTTCGGATGCC
  AACTGGCCCACTCCCCAAGCACTTGCCCCCAGCTTGCGACCATTGGCACTGGGAGGGCCT
  GGCTTCTGGGCTGATGGGTCAGTTGGGCCTTCATAAACACTCACCTGGCTGGCTTTGCCT
  TCCAGGAGGAAGCTGGCTGAAGCAAGGGTGTGGAATTTTAAATGTGTGCACAGTCTGGAA
  AACTGTCAGAATCAGTTTTCCCATAAAAGGGTGGGCTAGCATTGCAGCTGCATTTGGGAC
  CATTCAAATCTGTCACTCTCTTGTGTATATTCCTGTGCTATTAAATATATCAGGGCAGTG
  CATGTAAATCATCCTGATATATTTAATATATTTATTATATTGTCCCCCGAGGTGGGGACA
  GTGAGTGAGTTCTCTTAGTCCCCCCAGAGCTGGTTGTTAAAGAGCCTGGCACCTACCCGC
  TCTCACTTCATCTGTGTCATCTCTGCACACTCCAGCCCACTTTCTGCCTTCAGCCATTGA
  GTGGAAGCTGCCCCAGGCCCTTACCAGGTGCAGATGCCCAATCTTGATGCCCAGCCATCA
  GAACTGTGAGCCAAATAAACCTTTTTCTGTATAAATTAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001098628
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone has been fully sequenced and found one SNP within the protein associated with this reference, NM_001098628.1. This SNP doesn't change amino acid.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001098628.1, NP_001092098.1
• RefSeq Size: 2822 bp
• RefSeq ORF: 1467 bp
• Locus ID: 3663
• Cytogenetics: 7q32.1
• Protein Families: Transcription Factors
• Protein Pathways: Toll-like receptor signaling pathway
• Gene Summary: 'This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]'
  Transcript Variant: This variant (4) lacks two alternate in-frame segments compared to variant 5. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform d.