TMPRSS3 (NM_032405) Human Untagged Clone

CAT#: SC316502

TMPRSS3 (untagged)-Human transmembrane protease, serine 3 (TMPRSS3), transcript variant D

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TMPRSS3
• Synonyms: DFNB8; DFNB10; ECHOS1; TADG12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032405 edited
  GGAAAGGGCTGTGTTTATGGGAAGCCAGTAACACTGTGGCCTACTATCTCTTCCGTGGTG
  CCATCTACATTTTTGGGACTCGGGAATTATGAGGTAGAGGTGGAGGCGGAGCCGGATGTC
  AGAGGTCCTGAAATAGTCACCATGGGGGAAAATGATCCGCCTGCTGTTGAAGCCCCCTTC
  TCATTCCGATCGCTTTTTGGCCTTGATGATTTGAAAATAAGTCCTGTTGCACCAGATGCA
  GATGCTGTTGCTGCACAGATCCTGTCACTGCTGCCATTGAAGTTTTTTCCAATCATCGTC
  ATTGGGATCATTGCATTGATATTAGCACTGGCCATTGGTCTGGGCATCCACTTCGACTGC
  TCAGGGAAGTACAGATGTCGCTCATCCTTTAAGTGTATCGAGCTGATAGCTCGATGTGAC
  GGAGTCTCGGATTGCAAAGACGGGGAGGACGAGTACCGCTGTGTCCGGGTGGGTGGTCAG
  AATGCCGTGCTCCAGGTGTTCACAGCTGCTTCGTGGAAGACCATGTGCTCCGATGACTGG
  AAGGGTCACTACACAAATGTTGCCTGTGCCCAACTGGGTTTCCCAAGCTATGTGAGTTCA
  GATAACCTCAGAGTGAGCTCGCTGGAGGGGCAGTTCCGGGAGGAGTTTGTGTCCATCGAT
  CACCTCTTGCCAGATGACAAGGTGACTGCATTACACCACTCAGTATATGTGAGGGAGGGA
  TGTGCCTCTGGCCACGTGGTTACCTTGCAGTGCACAGCCTGTGGTCATAGAAGGGGCTAC
  AGCTCACGCATCGTGGGTGGAAACATGTCCTTGCTCTCGCAGTGGCCCTGGCAGGCCAGC
  CTTCAGTTCCAGGGCTACCACCTGTGCGGGGGCTCTGTCATCACGCCCCTGTGGATCATC
  ACTGCTGCACACTGTGTTTATGACTTGTACCTCCCCAAGTCATGGACCATCCAGGTGGGT
  CTAGTTTCCCTGTTGGACAATCCAGCCCCATCCCACTTGGTGGAGAAGATTGTCTACCAC
  AGCAAGTACAAGCCAAAGAGGCTGGGCAATGACATCGCCCTTATGAAGCTGGCCGGGCCA
  CTCACGTTCAATGGTACATCTGGGTCTCTATGTGGTTCTGCAGCTCTTCCTTTGTTTCAA
  GAGGATTTGCAATTGCTCATTGAAGCATTCTTATGATCTAGATT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032405 unedited
  GGGCTCCTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGGAAAGGGCT
  GTGTTTATGGGAAGCCAGTAACACTGTGGCCTACTATCTCTTCCGTGGTGCCATCTACAT
  TTTTGGGACTCGGGAATTATGAGGTAGAGGTGGAGGCGGAGCCGGATGTCAGAGGTCCTG
  AAATAGTCACCATGGGGGAAAATGATCCGCCTGCTGTTGAAGCCCCCTTCTCATTCCGAT
  CGCTTTTTGGCCTTGATGATTTGAAAATAAGTCCTGTTGCACCAGATGCAGATGCTGTTG
  CTGCACAGATCCTGTCACTGCTGCCATTGAAGTTTTTTCCAATCATCGTCATTGGGATCA
  TTGCATTGATATTAGCACTGGCCATTGGTCTGGGCATCCACTTCGACTGCTCAGGGAAGT
  ACAGATGTCGCTCATCCTTTAAGTGTATCGAGCTGATAGCTCGATGTGACGGAGTCTCGG
  ATTGCAAAGACGGGGAGGACGAGTACCGCTGTGTCCGGGTGGGTGGTCAGAATGCCGTGC
  TCCAGGTGTTCACAGCTGCTTCGTGGAAGACCATGTGCTCCGATGACTGGAAGGGTCACT
  ACACAAATGTTGCCTGTGCCCAACTGGGTTTCCCAAGCTATGTGAGTTCAGATAACCTCA
  GAGTGAGCTCGCTGGAGGGGCAGTTCCGGGAGGAGTTTGTGTCCATCGATCACCTCTTGC
  CAGATGACAAGGTGACTGCATTACACCACTCAGTATATGTGAGGGAGGGATGTGCCTCTG
  GCCACGTGGTTACCTTGCAGTGCACAGCCTGTGGTCATAGAAGGGCTACAGCTCACGCAT
  CGTGGGTGGAAACATGTCCTTGCTCTCGCAGTGGCCCTGGCAGGCCAGCCTTCAGTTTCA
  GGGCTACCACCTGGTGCGGGGGGCTTCTGTCATCACGCCCCTGTGTGGATTCATCACCTG
  CTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032405 unedited
  GGTTCGCGAGATGCTGAGATGCACTTCAGGCCGGAAGCACTGGGGAAGGGTCACAGGGAT
  GCCCCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGATCATAAGAAT
  GCTTCAATGAGCAATTGCAAATCCTCTTGAAACAAAGGAAGAGCTGCAGAACCACATAGA
  GACCCAGATGTACCATTGAACGTGAGTGGCCCGGCCAGCTTCATAAGGGCGATGTCATTG
  CCCAGCCTCTTTGGCTTGTACTTGCTGTGGTAGACAATCTTCTCCACCAAGTGGGATGGG
  GCTGGATTGTCCAACAGGGAAACTAGACCCACCTGGATGGTCCATGACTTGGGGAGGTAC
  AAGTCATAAACACAGTGTGCAGCAGTGATGATCCACAGGGGCGTGATGACAGAGCCCCCG
  CACAGGTGGTAGCCCTGGAACTGAAGGCTGGCCTGCCAGGGCCACTGCGAGAGCAAGGAC
  ATGTTTCCACCCACGATGCGTGAGCTGTAGCCCCTTCTATGACCACAGGCTGTGCACTGC
  AAGGTAACCACGTGGCCAGAGGCACATCCCTCCCTCACATATACTGAGTGGTGTAATGCA
  GTCACCTTGTCATCTGGCAAGAGGTGATCGATGGACACAAACTCCTCCCGGAACTGCCCC
  TCCAGCGAGCTCACTCTGAGGTTATCTGAACTCACATAGCTTGGGAAACCCAGTTGGGCA
  CAGGCAACATTTGTGTAGTGACCCTTCCAGTCATCGGAGCACATGGTCTTCCACGAAGCA
  GCTGTGAACACCTGGAGCACGGCATTCTGACCACCCCACCCGGACACAGCGGTACTCGTC
  CTCCCGTCTTTGCAATCCGAGACTCCGTCACCATCGAGCTATCAGCTCGATACACTTAAA
  GGATGAGCGACATCTGTACTTCCCTGAGCAGTCGA
  
• Restriction Sites: Please inquire
• ACCN: NM_032405
• ORF Size: 1035 bp
• Insert Size: 1200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_032405.1, NP_115781.1
• RefSeq Size: 1359
• RefSeq ORF: 1035
• Locus ID: 64699
• Domains: SR, Tryp_SPc, ldl_recept_a
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
  Transcript Variant: This variant (D) lacks several 3' exons, but includes an alternate 3' exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant A. The encoded isoform (3) has a distinct and shorter C-terminus, compared to isoform 1.