Septin 8 (SEPT8) (NM_015146) Human Untagged Clone

CAT#: SC316521

41525 (untagged)-Human septin 8 (SEPT8), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEPT8
• Synonyms: SEP2; SEPT8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015146, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCACCGACCTGGAGCGCTTCTCGAATGCAGAGCCAGAGCCCCGGAGCCTCTCCCTGGGCGGCC
  ATGTGGGTTTCGACAGCCTCCCCGACCAGCTGGTCAGCAAGTCGGTCACTCAGGGCTTCAGCTTCAACAT
  CCTCTGTGTGGGGGAGACCGGCATTGGCAAATCCACACTGATGAACACACTCTTCAACACGACCTTCGAG
  ACTGAGGAAGCCAGTCACCATGAGGCATGCGTGCGCCTGCGGCCCCAGACCTATGACCTCCAGGAGAGCA
  ACGTGCAGCTCAAGCTGACCATTGTGGATGCCGTGGGCTTTGGGGATCAGATCAATAAGGATGAGAGTTA
  CAGGCCCATAGTTGACTACATCGATGCGCAGTTTGAAAATTATCTGCAGGAGGAGCTGAAGATCCGCCGC
  TCGCTCTTCGACTACCATGACACAAGGATCCACGTTTGCCTCTACTTCATCACGCCCACAGGGCACTCCC
  TGAAGTCTCTAGATCTAGTGACCATGAAGAAACTAGACAGCAAGGTGAACATTATTCCCATCATCGCCAA
  GGCTGACACCATCTCCAAGAGCGAGCTCCACAAGTTCAAGATCAAGATCATGGGCGAGTTGGTCAGCAAC
  GGGGTCCAGATCTACCAGTTCCCCACGGATGATGAGGCTGTTGCAGAGATTAACGCAGTCATGAATGCAC
  ATCTGCCCTTTGCCGTGGTGGGCAGCACCGAGGAGGTGAAGGTGGGGAACAAGCTGGTCCGAGCACGGCA
  GTACCCCTGGGGAGTGGTGCAGGTGGAGAATGAGAATCACTGCGACTTCGTGAAGCTGCGGGAGATGTTG
  ATCCGGGTGAACATGGAAGACCTCCGCGAGCAGACCCACAGCCGGCACTACGAGCTCTACCGGCGCTGCA
  AGTTGGAGGAGATGGGCTTTCAGGACAGCGATGGTGACAGCCAGCCCTTCAGCCTACAAGAGACATACGA
  GGCCAAGAGGAAGGAGTTCCTAAGTGAGCTGCAGAGGAAGGAGGAAGAGATGAGGCAGATGTTTGTCAAC
  AAAGTGAAGGAGACAGAGCTGGAGCTGAAGGAGAAGGAAAGGGAGCTCCATGAGAAGTTTGAGCACCTGA
  AGCGGGTCCACCAGGAGGAGAAGCGCAAGGTGGAGGAAAAGCGCCGGGAACTGGAGGAGGAGACCAACGC
  CTTCAATCGCCGGAAGGCTGCGGTGGAGGCCCTGCAGTCGCAGGCCTTGCACGCCACCTCGCAGCAGCCC
  CTGAGGAAGGACAAGGACAAGAAGAATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015146
• ORF Size: 1290 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015146.1, NP_055961.1
• RefSeq Size: 4344
• RefSeq ORF: 1290
• Locus ID: 23176
• Gene Summary: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (2) differs in the 3' UTR and lacks a portion of the 3' coding region compared to variant 1. The resulting isoform (b) is shorter at the C-terminus compared to isoform a.