KCNK10 (NM_138318) Human Untagged Clone

CAT#: SC316623

KCNK10 (untagged)-Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNK10
• Synonyms: K2p10.1; PPP1R97; TREK-2; TREK2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138318, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGATGGATTTAAGGGGGACAGGACTGAAGGCTGTCGCAGTGATTCAGTGGCCGTTCCCGCAGCAG
  CACCGGTGTGCCAGCCCAAGAGCGCCACTAACGGGCAACCCCCGGCTCCGGCTCCGACTCCAACTCCGCG
  CCTGTCCATTTCCTCCCGAGCCACAGTGGTAGCCAGGATGGAAGGCACCTCCCAAGGGGGCTTGCAGACC
  GTCATGAAGTGGAAGACGGTGGTTGCCATCTTTGTGGTTGTGGTGGTCTACCTTGTCACTGGCGGTCTTG
  TCTTCCGGGCATTGGAGCAGCCCTTTGAGAGCAGCCAGAAGAATACCATCGCCTTGGAGAAGGCGGAATT
  CCTGCGGGATCATGTCTGTGTGAGCCCCCAGGAGCTGGAGACGTTGATCCAGCATGCTCTTGATGCTGAC
  AATGCGGGAGTCAGTCCAATAGGAAACTCTTCCAACAACAGCAGCCACTGGGACCTCGGCAGTGCCTTTT
  TCTTTGCTGGAACTGTCATTACGACCATAGGGTATGGGAATATTGCTCCGAGCACTGAAGGAGGCAAAAT
  CTTTTGTATTTTATATGCCATCTTTGGAATTCCACTCTTTGGTTTCTTATTGGCTGGAATTGGAGACCAA
  CTTGGAACCATCTTTGGGAAAAGCATTGCAAGAGTGGAGAAGGTCTTTCGAAAAAAGCAAGTGAGTCAGA
  CCAAGATCCGGGTCATCTCAACCATCCTGTTCATCTTGGCCGGCTGCATTGTGTTTGTGACGATCCCTGC
  TGTCATCTTTAAGTACATCGAGGGCTGGACGGCCTTGGAGTCCATTTACTTTGTGGTGGTCACTCTGACC
  ACGGTGGGCTTTGGTGATTTTGTGGCAGGGGGAAACGCTGGCATCAATTATCGGGAGTGGTATAAGCCCC
  TAGTGTGGTTTTGGATCCTTGTTGGCCTTGCCTACTTTGCAGCTGTCCTCAGTATGATCGGAGATTGGCT
  ACGGGTTCTGTCCAAAAAGACAAAAGAAGAGGTGGGTGAAATCAAGGCCCATGCGGCAGAGTGGAAGGCC
  AATGTCACGGCTGAGTTCCGGGAGACACGGCGAAGGCTCAGCGTGGAGATCCACGATAAGCTGCAGCGGG
  CGGCCACCATCCGCAGCATGGAGCGCCGGCGGCTGGGCCTGGACCAGCGGGCCCACTCACTGGACATGCT
  GTCCCCCGAGAAGCGCTCTGTCTTTGCTGCCCTGGACACCGGCCGCTTCAAGGCCTCATCCCAGGAGAGC
  ATCAACAACCGGCCCAACAACCTGCGCCTGAAGGGGCCGGAGCAGCTGAACAAGCATGGGCAGGGTGCGT
  CCGAGGACAACATCATCAACAAGTTCGGGTCCACCTCCAGACTCACCAAGAGGAAAAACAAGGACCTCAA
  AAAGACCTTGCCCGAGGACGTTCAGAAAATCTACAAGACCTTCCGGAATTACTCCCTGGACGAGGAGAAG
  AAAGAGGAGGAGACGGAAAAGATGTGTAACTCAGACAACTCCAGCACAGCCATGCTGACGGACTGTATCC
  AGCAGCACGCTGAGTTGGAGAACGGAATGATACCCACGGACACCAAAGACCGGGAGCCGGAGAACAACTC
  ATTACTTGAAGACAGAAACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138318 unedited
  GTGCCTTGTATACGACTCCTATAGGGCGGCCGCGAATTCATGGAGGATGGATTTAAGGGG
  GACAGGACTGAAGGCTGTCGCAGTGATTCAGTGGCCGTTCCCGCAGCAGCACCGGTGTGC
  CAGCCCAAGAGCGCCACTAACGGGCAACCCCCGGCTCCGGCTCCGACTCCAACTCCGCGC
  CTGTCCATTTCCTCCCGAGCCACAGTGGTAGCCAGGATGGAAGGCACCTCCCAAGGGGGC
  TTGCAGACCGTCATGAAGTGGAAGACGGTGGTTGCCATCTTTGTGGTTGTGGTGGTCTAC
  CTTGTCACTGGCGGTCTTGTCTTCCGGGCATTGGAGCAGCCCTTTGAGAGCAGCCAGAAG
  AATACCATCGCCTTGGAGAAGGCGGAATTCCTGCGGGATCATGTCTGTGTGAGCCCCCAG
  GAGCTGGAGACGTTGATCCAGCATGCTCTTGATGCTGACAATGCGGGAGTCAGTCCAATA
  GGAAACTCTTCCAACAACAGCAGCCACTGGGACCTCGGCAGTGCCTTTTTCTTTGCTGGA
  ACTGTCATTACGACCATAGGGTATGGGAATATTGCTCCGAGCACTGAAGGAGGCAAAATC
  TTTTGTATTTTATATGCCATCTTTGGAATTCCACTCTTTGGTTTCTTATTGGCTGGAATT
  GGAGACCAACTTGGAACCATCTTTGGGAAAAGCATTGCAAGAGTGGAGAAGTCTTTCGAA
  AAAAGCAAGTGAGTCAGACCAAGATCCCGGGTCATCTCAACCATCCTGTTCATCTTGGCC
  GGCTGCATTGTGTTTGTGACGATCCCTGCTGTCATCTTTAGTACATCGAGGGCTGACGCC
  TTGAGTCCATTTACTTTGTGTGTCACTCTGAACACGTGGGCTTTGTGATTTGTGCAGGGG
  AACGCTGGCATCATTATCGGGAGTGGTATTAAGCCCCCTAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_138318 unedited
  CGCTGATGCACTTCAGGGCCGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGG
  ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT
  TTTTTTTTTTTTGACATTTCCAAATCAGTTTATTGTCACCATTGCACCCACTGAGGAAAA
  TGCATGATTGGCCTTTAACCACGCAGCAGTTGATGTCATGTTTTCACCACTGCTCGCCAG
  TTCATGTGGACTACCTACCCCTGTGAAAAAAACCAAACTCAGCAGGCTTCTGTCATTGGT
  TAAGGTGATATCCACAGTGTGATGTGTTTGTGATTATTTTTTTTCTTTTGTCATGAAAAA
  AGCAATTGCACCTTTTCGTACGTGTGCTCTGATCTGCTTCCAACAAATTCCAGGTGCTCT
  CAGGTCCCCACAGACATTCATTTGGAGCATAAAAAGACTAGGTATGATGCACTGAATGGT
  TGGTATCAAAATTCAAGCTCAGAGCACATGCCAAAATGTCAACTCCAACGCTAGTTACAC
  ATAACCAGCTCCCACCCAATCAGGTCCCCTTCTGTGTGTGCACATATTACTACGACTCCA
  CTAAAAAGACACACCTGTTTCTTTCAGGAGGCTGGTCTAAGGAATAGCTGCCCTTGTCTA
  CGTGTGTGCCCAGGTAGCACTGCCCAGGGGTACAGCACTGCCACTGAAATGCCCTTAACA
  TGTACGCCAGAACCGGCTACGTGCACGGACACTCTTGGTGTGTCTGCGTTTGCTATCTGA
  AATGAAGTTCTTGTCTCTGATCCTTTGCAGAGCAGCTTTCAGTGTGATGGCACAGTGAAA
  TATATTCTCATGCTATGTATTGACTAAAAGTCTGTTTAGCACATGTCTCATGTGAATATT
  AAAACAC
  
• Restriction Sites: Please inquire
• ACCN: NM_138318
• ORF Size: 1632 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_138318.1, NP_612191.1
• RefSeq Size: 2401
• RefSeq ORF: 1632
• Locus ID: 54207
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]
  Transcript Variant: This variant (3, also known as TREK2 splice variant b) has a different 5' terminal exon compared to transcript variant 1, and encodes a slightly longer isoform (3) with a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.