ADAM11 (NM_002390) Human Untagged Clone

CAT#: SC316966

ADAM11 (untagged)-Human ADAM metallopeptidase domain 11 (ADAM11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAM11
• Synonyms: MDC
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002390, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGCTGCTGCGGCGCTGGGCGTTCGCGGCTCTGCTGCTGTCGCTGCTCCCCACGCCCGGTCTTGGGA
  CCCAAGGTCCTGCTGGAGCTCTGCGATGGGGGGGCTTACCCCAGCTGGGAGGCCCAGGAGCCCCTGAGGT
  CACGGAACCCAGCCGTCTGGTTAGGGAGAGCTCCGGGGGAGAGGTCCGAAAGCAGCAGCTGGACACAAGG
  GTCCGCCAGGAGCCACCAGGGGGCCCGCCTGTCCATCTGGCCCAGGTGAGTTTCGTCATCCCAGCCTTCA
  ACTCAAACTTCACCCTGGACCTGGAGCTGAACCACCACCTCCTCTCCTCGCAATACGTGGAGCGCCACTT
  CAGCCGGGAGGGGACAACCCAGCACAGCACCGGGGCTGGAGACCACTGCTACTACCAGGGGAAGCTCCGG
  GGGAACCCGCACTCCTTCGCCGCCCTCTCCACCTGCCAGGGGCTGCATGGGGTCTTCTCTGATGGGAACT
  TGACTTACATCGTGGAGCCCCAAGAGGTGGCTGGACCTTGGGGAGCCCCTCAGGGACCCCTTCCCCACCT
  CATTTACCGGACCCCTCTCCTCCCAGATCCCCTCGGATGCAGGGAACCAGGCTGCCTGTTTGCTGTGCCT
  GCCCAGTCGGCTCCTCCAAACCGGCCGAGGCTGAGAAGGAAAAGGCAGGTCCGCCGGGGCCACCCTACAG
  TGCACAGTGAAACCAAGTATGTGGAGCTAATTGTGATCAACGACCACCAGCTGTTCGAGCAGATGCGACA
  GTCGGTGGTCCTCACCAGCAACTTTGCCAAGTCCGTGGTGAACCTGGCCGATGTGATATACAAGGAGCAG
  CTCAACACTCGCATCGTCCTGGTTGCCATGGAAACATGGGCAGATGGGGACAAGATCCAGGTGCAGGATG
  ACCTCCTGGAGACCCTGGCCCGGCTCATGGTCTACCGACGGGAGGGTCTGCCTGAGCCCAGTGATGCCAC
  CCACCTCTTCTCGGGCAGGACCTTCCAGAGCACGAGCAGCGGGGCAGCCTACGTGGGGGGCATATGCTCC
  CTGTCCCACGGCGGGGGTGTGAACGAGTACGGCAACATGGGGGCGATGGCCGTGACCCTTGCCCAGACGC
  TGGGACAGAACCTGGGCATGATGTGGAACAAACACCGGAGCTCGGCAGGGGACTGCAAGTGTCCAGACAT
  CTGGCTGGGCTGCATCATGGAGGACACTGGGTTCTACCTGCCCCGCAAGTTCTCGCGCTGTAGCATCGAC
  GAGTACAACCAGTTTCTGCAGGAGGGTGGTGGCAGCTGCCTCTTCAACAAGCCCCTCAAGCTCCTGGACC
  CCCCAGAGTGCGGGAACGGCTTCGTGGAGGCAGGGGAGGAGTGCGACTGCGGCTCGGTGCAGGAGTGCAG
  CCGCGCAGGTGGCAACTGCTGCAAGAAATGCACCCTGACTCACGACGCCATGTGCAGCGACGGGCTCTGC
  TGTCGCCGCTGCAAGTACGAACCACGGGGTGTGTCCTGCCGAGAGGCCGTGAACGAGTGCGACATCGCGG
  AGACCTGCACCGGGGACTCTAGCCAGTGCCCGCCTAACCTGCACAAGCTGGACGGTTACTACTGTGACCA
  TGAGCAGGGCCGCTGCTACGGAGGTCGCTGCAAAACCCGGGACCGGCAGTGCCAGGTTCTTTGGGGCCAT
  GCGGCTGCTGATCGCTTCTGCTACGAGAAGCTGAATGTGGAGGGGACGGAGCGTGGGAGCTGTGGGCGCA
  AGGGATCTGGCTGGGTCCAGTGCAGTAAGCAGGACGTGCTGTGTGGCTTCCTCCTCTGTGTCAACATCTC
  TGGAGCTCCTCGGCTAGGGGACCTGGTGGGAGACATCAGTAGTGTCACCTTCTACCACCAGGGCAAGGAG
  CTGGACTGCAGGGGAGGCCACGTGCAGCTGGCGGACGGCTCTGACCTGAGCTATGTGGAGGATGGCACAG
  CCTGCGGGCCTAACATGTTGTGCCTGGACCATCGCTGCCTGCCAGCTTCTGCCTTCAACTTCAGCACCTG
  CCCCGGCAGTGGGGAGCGCCGGATTTGCTCCCACCACGGGGTCTGCAGCAATGAAGGGAAGTGCATCTGT
  CAGCCAGACTGGACAGGCAAAGACTGCAGTATCCATAACCCCCTGCCCACGTCCCCACCCACGGGGGAGA
  CGGAGAGATATAAAGGTCCCAGCGGCACCAACATCATCATTGGCTCCATTGCTGGGGCTGTCCTGGTTGC
  AGCCATCGTCCTGGGCGGCACGGGCTGGGGATTTAAAAACATTCGCCGAGGAAGGTCCGGAGGGGCCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_002390
• ORF Size: 2310 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_002390.5, NP_002381.2
• RefSeq Size: 4439
• RefSeq ORF: 2310
• Locus ID: 4185
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).