PHYH (NM_006214) Human Untagged Clone

CAT#: SC316991

PHYH (untagged)-Human phytanoyl-CoA 2-hydroxylase (PHYH), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PHYH
• Synonyms: LN1; LNAP1; PAHX; PHYH1; RD
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006214, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCAGCTTCGCGCCGCCGCCCGTCTGCAGATTGTTCTGGGCCACCTCGGCCGCCCCTCGGCCGGGG
  CTGTCGTAGCTCATCCCACTTCAGGGACTATTTCCTCTGCCAGTTTCCATCCTCAACAATTCCAGTATAC
  TCTGGATAATAACGTTCTAACCCTGGAACAGAGAAAATTTTATGAAGAAAATGGGTTTCTAGTAATCAAA
  AATCTTGTACCTGATGCCGATATTCAACGCTTTCGGAATGAGTTTGAAAAAATCTGCAGAAAGGAGGTGA
  AACCATTAGGATTAACAGTAATGAGAGATGTGACCATTTCGAAATCCGAATATGCTCCAAGTGAGAAGAT
  GATCACGAAGGTCCAGGATTTCCAGGAAGATAAGGAGCTCTTCAGATACTGCACTCTCCCCGAGATTCTG
  AAATATGTGGAGTGCTTCACTGGACCTAATATTATGGCCATGCACACAATGTTGATAAACAAACCTCCAG
  ATTCTGGCAAGAAGACGTCCCGTCACCCCCTGCACCAGGACCTGCACTATTTCCCCTTCAGGCCCAGCGA
  TCTCATCGTTTGCGCCTGGACGGCGATGGAGCACATCAGCCGGAACAACGGCTGTCTGGTTGTGCTCCCA
  GGCACACACAAGGGCTCCCTGAAGCCCCACGATTACCCCAAGTGGGAGGGGGGAGTTAACAAAATGTTCC
  ACGGGATCCAGGACTACGAGGAAAACAAGGCCCGGGTGCACCTGGTGATGGAGAAGGGCGACACTGTTTT
  CTTCCATCCTTTGCTCATCCACGGATCTGGTCAGAATAAAACCCAGGGATTCCGGAAGGCAATTTCCTGC
  CATTTCGCCAGTGCCGATTGCCACTACATTGACGTGAAGGGCACCAGTCAAGAAAACATCGAGAAGGAAG
  TTGTAGGAATAGCACATAAATTCTTTGGAGCTGAAAATAGCGTGAACTTGAAGGATATTTGGATGTTTCG
  AGCTCGACTTGTGAAAGGAGAAAGAACCAATCTTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006214 unedited
  GCTACATTGTATACGACTCCTATAGGGCGGCCGCGCCCCTACGGCACCAGGCTGGGCTAA
  ATGGGGCAGAGGCCGGGAGGGGTGGGGGTTCCCCGCGCCGCAGCCATGGAGCAGCTTCGC
  GCCGCCGCCCGTCTGCAGATTGTTCTGGGCCACCTCGGCCGCCCCTCGGCCGGGGCTGTC
  GTAGCTCATCCCACTTCAGGGACTATTTCCTCTGCCAGTTTCCATCCTCAACAATTCCAG
  TATACTCTGGATAATAATGTTCTAACCCTGGAACAGAGAAAATTTTATGAAGAAAATGGG
  TTTCTAGTAATCAAAAATCTTGTACCTGATGCCGATATTCTACGCTTTCGGAATGAGTTT
  GAAAAAATCTGCAGAAAGGAGGTGAAACCATTAGGATTAACAGTAATGAGAGATGTGACC
  ATTTCGAAATCCGAATATGCTCCAAGTGAGAAGATGATCACGAAGGTCCAGGATTTCCAG
  GAAGATAAGGAGCTCTTCAGATACTGCACTCTCCCCGAGATTCTGAAATATGTGGAGTGC
  TTCACTGGACCTAATATTATGGCCATGCACACAATGTTGATAAACAAACCTCCAGATTCT
  GGCAAGAAGACGTCCCGTCACCCCCTGCACCAGGACCTGCACTATTTCCCCTTCAGCCCA
  GCGATCTCATCGTTTGCGCCTGGACGGCGATGGAGCACATCAGCCGGAACAACGGCTGTC
  TGGTTGTGCTCCCAGGCACACACAAAGGGCTCCCTGAAGCCCCACGATTACCCCAAGTGG
  GAGGGGGAGTTAACAAAATGTTCCACGGGATCCAGGACTACGAGGAAAACAAGCCCGGGT
  GCCACCTGGTGATGGAGAAGGCGAACACTGTTTTCTTCCATCCTTTGCTCATCCACGATC
  TGTCAAGAAATAAAACCCAAGGGAATCCCGAAGGCAATTCCCTGGCCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006214 unedited
  CGAGAGATGCACCTTCCGGGCCGGAGAGGCACGGGGGAGGGGTCACAGGGATGCCACCCG
  GGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTT
  TTTTTTTTTTTTTTCCGAGCAGGAATATCCACTTTATTTGGACTCCATGACACCGTTCCT
  ATGCCCTTGACTAGATGTGAATGTATTATACATTGTTCTAAATTTGGGGGAAAAAAATCT
  CTTATGACATAAAATTGGTAGGGAATGGGTTTATCAAAAAGGGGATACAAAACATACCCT
  AAGCTCCAAATCATTCACTTCTTCTTGGGTAAAGAGCTAACTGAATGAAAAAAATTGATT
  TAACACTTAAATTAAACACCAACCACCTTTATTGGCTGCCACCCTAAATTAGTTTTCCTT
  AAAACAGTAATATTTCACTTTTACTGTTTTTTTTTCCATTAAAGCAACACCATTGTGCTG
  CAAAACTAACTCTATGCAATTAAGTACCTGATACATGTTTTCTGCTTTTAACAAGTGATA
  GAAAAGGTTACATCATCTCATTAAAAAAACATTTTCCTTAGACATTTCGTTTGGTTTTGG
  TTTTCTGTTGAAAGAGTTATAGCAGATGGCTATTTTCAAAGATTGGTTCTTTCTCCTTTC
  ACAAGTCGAGCTCGAAAACATCCAAATATCCTTCAAGTTCACGCTATTTTCAGCTCCAAA
  GAATTTATGTGCTATTCCTACACTTCCTTCTCGATGTTTTCTTGACTGTGCCCTTCACGT
  CAATGTAGTGGCATCGGCACTGCGAAATGGCAGAAATTGCCTCGATCCCTGGGTTTTATT
  CTGACCAGATCCGTGGATGAGCAGATGAAGAAAACATGTCGCTCTCCATCACAGTGCACG
  CTGTTCCTCGAGTCTGATCGTGACATTTGTACTCCCCCTCCACTTCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006214
• ORF Size: 1017 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006214.3, NP_006205.1
• RefSeq Size: 1620
• RefSeq ORF: 1017
• Locus ID: 5264
• Protein Families: Druggable Genome
• Gene Summary: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes isoform a.