SPAG11B (NM_058207) Human Untagged Clone

CAT#: SC317220

SPAG11B (untagged)-Human sperm associated antigen 11B (SPAG11B), transcript variant E

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPAG11B
• Synonyms: EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11; SPAG11A
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_058207, the custom clone sequence may differ by one or more nucleotides
  ATGAAGGTCTTTTTTCTGTTTGCTGTTCTCTTTTGTTTGGTCCAAACAAACTCAGGGGAT
  GTTCCACCGGGAATTAGAAATACCATCTGCCATATGCAGCAAGGGATCTGCAGACTTTTT
  TTCTGCCATTCTGGTGAGAAAAAGCGTGACATTTGCTCTGATCCCTGGAATAGGTGTTGC
  GTATCAAATACAGATGAAGAAGGAAAAGAGAAACCAGAGATGGATGGCAGATCTGGGATC
  
• Restriction Sites: Please inquire
• ACCN: NM_058207
• ORF Size: 243 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_058207.2, NP_478114.2
• RefSeq Size: 444
• RefSeq ORF: 243
• Locus ID: 10407
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (E) has an alternate 5' UTR and lacks one internal exon, compared to variant A. The N-terminus of the encoded isoform (E) is identical to isoform B, and its C-terminus is identical to isoform D. Isoform E has a region of similarity to beta-defensins. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on orthologous transcript alignments and on data in PMID: 15229135.